Results 31 to 40 of about 669 (167)
Recent Advances in Antimalarial Drug Discovery — Challenges and Opportunities [PDF]
, 2015 Malaria drug discovery is a challenging and difficult task due to the unavailability of the vaccine and lack of newer drugs. The most potent artemisinin and its derivatives, widely used in combination therapies for curing malaria worldwide are also now ...
Awasthi, Satish Kumar +1 more
core +2 more sources
Continuous flow photooxidation of p-substituted phenols using singlet oxygen in supercritical CO2 applied to telescoped syntheses [PDF]
, 2021 Interest in photochemical processes both in academia and industry is increasing, but uptake is still limited due to low efficiency and/or scalability of current processes.
Abreu, Bruna
core +3 more sources
A Review on Antimalarial 1,2,4-Trioxane Derivatives
Journal of Drug Delivery and Therapeutics, 2020 Malaria in recent years becomes a major health hitch globally due to the surfacing of multidrug-resistant strains of Plasmodium falciparum parasite. In recent times, artemisinin (ART)-based drugs and combination therapies become the drugs of preference for the treatment and prophylaxis of resistant P. falciparum malaria. Endoperoxide compounds natural,
Kamya Goyal +4 more
openaire +2 more sources
A kinetic and mechanistic study on the thermal decomposition reactions of cis- and trans- fused 1,2,4-trioxanes [PDF]
, 2020 The kinetics of the thermal decomposition reactions of artemisinine (1), a cis-fused 1,2,4-trioxane, and trans-3,3dimethyl-1,2,4-trioxane (6) in solutions of benzene, toluene, and methanol in sealed tubes were compared at temperatures between 100.1° and ...
Cafferata, Lázaro F. R. +4 more
core +2 more sources
Effects of Different Methods of Isolation on Volatile Composition of Artemisia annua L.
International Journal of Analytical Chemistry, Volume 2018, Issue 1, 2018., 2018 In order to determine influence of extraction method on volatile oil composition of Artemisia annua L., steam distillation, hydrodistillation, organic solvent extraction, and headspace sampling have been applied. The relative abundance of volatile compounds from the odorous aerial parts of A.
Danijela Vidic +4 more
wiley +1 more source
Cinètica de la reacció de descomposició tèrmica de l’ascaridol en dissolució [PDF]
, 2005 Existen diferencias entre los valores de algunas propiedades físicas de ascaridol natural aislado del vegetal denominado vulgarmente «Paico» (Chenopodium ambrosioides L., Chenopodiaceae) y la sustancia sintética obtenida mediante la reacción de ...
Cafferata, Lazaro +2 more
core +1 more source
Analytical Science Advances, Volume 7, Issue 1, June 2026.ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Eduard F. Valenzuela +7 more
wiley +1 more source
Preparation and Characterization of Solid Dispersions of Artemether by Freeze‐Dried Method
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 Solid dispersions of artemether and polyethylene glycol 6000 (PEG6000) were prepared in ratio 12 : 88 (group‐1). Self‐emulsified solid dispersions of artemether were prepared by using polyethylene glycol 6000, Cremophor‐A25, olive oil, Transcutol, and hydroxypropyl methylcellulose (HPMC) in ratio 12 : 75 : 5 : 4 : 2 : 2, respectively (group‐2).
Muhammad Tayyab Ansari +9 more
wiley +1 more source
The synthesis and reactions of some potentially antimalarial 1,2,4-trioxanes [PDF]
, 1994 A series of potentially antimalarial 1,2,4-trioxanes were prepared by the electrophile-mediated cyclisation of allylic hemiperoxyacetals. The starting allylic hemiperoxyacetals were obtained by the addition of allylic hydroperoxides to aldehydes and ...
Shah, Aneela
core
Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites
ChemMedChem, Volume 20, Issue 11, June 2, 2025.Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert +6 more
wiley +1 more source