Results 11 to 20 of about 1,058 (166)

Pd(II)/PIDA-Enabled Migratory Triple Functionalization of Terminal Alkenes via a 1,2-C/Pd(IV) Dyotropic Rearrangement. [PDF]

Angew Chem Int Ed Engl
Pd‐catalyzed reaction of homoallylic amides with phenyliodine(III) diacetate (PIDA) under Pd(II) catalysis delivers 6‐acetoxylated 5,6‐dihydro‐4H‐1,3‐oxazines through the formation of one C─C and two C─O bonds. Abstract We report a Pd(II)‐catalyzed migratory triple functionalization of terminal alkenes.
Liu CX, Wang Q, Zhu J.
europepmc   +3 more sources

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

Biotechnology Reports, 2020
Constitutive activation of NF-κB is associated with proinflammatory diseases and suppression of the NF-κB signaling pathway has been considered as an effective therapeutic strategy in the treatment of various cancers including hepatocellular carcinoma ...
Chaithanya Somu, Chakrabhavi Dhananjaya Mohan, Sachin Ambekar, Dukanya, Shobith Rangappa, CP Baburajeev, Alexey Sukhorukov, Srishti Mishra, Muthu K Shanmugam, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Basappa, Kanchugarakoppal S. Rangappa   +13 more
doaj   +1 more source

Cyclization of Hydrazones of 2-Acetyl-1-naphthol and 1-Acetyl-2-naphthol with Triphosgene. Synthesis of Spiro Naphthoxazine Dimers

Molecules, 2009
Cyclization of hydrazones derived from 2-acetyl-1-naphthol and 1-acetyl-2-naphthol with triphosgene gave naphtho[1,2-e]-1,3-oxazines, naphtho[2,1-e]-1,3-oxazines or their spiro dimers depending on the molar ratio of triphosgene used for the cyclization.
Hamad Zaid Alkhathlan, Sara Abdullah Al-Mazroa, Ahmed Amine Mousa, Mohammed Ali Al-Saad, Abdullah Mohammed Al-Majid, Abdullah Saad Al-Bogami   +5 more
doaj   +1 more source

Efficient synthesis of 1,3-naphtoxazine derivatives using reusable magnetic catalyst (GO-Fe3O4–Ti(IV)): anticonvulsant evaluation and computational studies

BMC Chemistry, 2022
A series of 2-aryl/alkyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines (S 1 –S 11 ) were synthesized with an eco-friendly and recoverable nanocatalyst (GO-Fe3O4–Ti(IV)) as an efficient magnetic composite. The new nanocatalyst was characterized by FT-IR, XRD
Soghra Khabnadideh, Aida solhjoo, Reza Heidari, Leila Amiri Zirtol, Amirhossein Sakhteman, Zahra Rezaei, Elaheh Babaei, Samaneh Rahimi, Leila Emami   +8 more
doaj   +1 more source

Synthesis and characterization of novel 1,2-oxazine-based small molecules that targets acetylcholinesterase [PDF]

, 2014
Thirteen 2-oxazine-based small molecules were synthesized targeting 5-lipoxygenase (LOX), and acetylcholinesterase (AChE). The test revealed that the newly synthesized compounds had potent inhibition towards both 5-LOX and AChE in lower micro molar ...
Basappa, ., Ioffe, S.L., Nanjunda Swamy, S., Nirvanappa, A.C., Rangappa, K.S., Sukhorukov, A.Y., Swamy, J.   +6 more
core   +1 more source

The [4+2] cycloaddition of donor-acceptor cyclobutanes and nitrosoarenes. [PDF]

, 2014
The Yb(OTf)3 catalyzed [4+2] cycloaddition between donor-acceptor cyclobutanes and nitrosoarenes is disclosed. This method facilitates the synthesis of tetrahydro-1,2-oxazines in good to excellent yields as single diastereomers. Except for a few electron-
Pagenkopf, Brian L, Schon, Tyler B, Stevens, Andrew C, Vemula, Naresh   +3 more
core   +4 more sources

an Experimental and Computational Study [PDF]

, 2020
To gain a deeper understanding of the formation of the synthetically important 3,6‐dihydro‐2H‐1,2‐oxazines, the 6‐endo‐trig cyclization of allenyl‐substituted hydroxylamines was experimentally investigated in detail employing a model compound.
Jasiński, Marcin, Reissig, Hans‐Ulrich, Utecht‐Jarzyńska, Greta, Würthwein, Ernst‐Ulrich   +3 more
core   +1 more source

Synthesis of New 1,3-Disubstituted-2,3-dihydro-1H-naphth[1,2e][1,3]oxazines

Molecules, 2007
1,3-Disubstituted-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines were prepared through the ring-closurereactions of the aminobenzylnaphthols with substituted aryl-andheteroarylaldehydes.
Adem Köycü, Emel Pelit, Zuhal Turgut
doaj   +1 more source

Synthesis of 2-substituted benzimidazole, coumarin, benzo[b][1,4]oxazin and dihydropyrimidinone derivatives using core-shell structured Fe3O4@SiO2-ZnCl2 nanoparticles as an effective catalyst

Results in Chemistry, 2020
In this paper, a magnetic nanocatalyst of Fe3O4@SiO2-ZnCl2 has been used which enhances the synthesis of benzimidazoles, coumarins, benzoxazines and dihydropyrimidinones. To begin with, 2-substituted benzimidazoles have been synthesized in proper to high
Saba Rahimi, Ebrahim Soleimani
doaj   +1 more source

Synthesis and characterization of novel oxazines and demonstration that they specifically target cyclooxygenase 2 [PDF]

, 2015
In the present study, we used solution combustion synthesis-bismuth oxide (Bi2O3) as catalyst for the simple and efficient synthesis of 1,2-oxazine based derivatives of 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazoles, 1-arylpiperazine and carbazoles.
Baburajeev, C.P., Basappa, ., Bender, A., Chandra, ., Fuchs, J.E., Jagadish, S., Madegowda, M., Mason, D.J., Mohan, C.D., Rangappa, K.S., Rangappa, S., Sharath Kumar, K.S., Srinivas, V., Sukhorukov, A.Y.   +13 more
core   +1 more source