Results 41 to 50 of about 1,058 (166)

Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso, José A. Paixão, Teresa M. V. D. Pinho e Melo   +2 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, Volume 20, Issue 3, Page 688-708, March 2026.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Effect of α‐Hydrazino Acids on the Performance of H‐Pro–Pro‐Xaa Catalysts in the Conjugate Addition of Aldehydes to Nitroolefins

ChemistrySelect, Volume 11, Issue 11, 18 March 2026.
The tripeptide Pro‐Pro‐D‐hVal‐OMe, which lacks an acidic group, catalysed the conjugate addition of aldehydes to nitroolefins and afforded γ‐nitroaldehydes in 79–97% yield and 88:14–93:7 e.r. The proposed reaction mechanism relies on the active role of hydrazide NHβ or NHα protons in hydrogen bonding with the reacting species.
Ivona Banović, Ivana Nikšić‐Franjić, Ivanka Jerić   +2 more
wiley   +1 more source

Addition and cycloaddition reactions of Phosphinyl- and Phosphonyl-2H-Azirines, Nitrosoalkenes and Azoalkenes [PDF]

, 2012
An overview of the use of 2H-azirines, conjugated nitrosoalkenes and conjugated azoalkenes bearing phosphorus substituents in addition and cycloaddition reactions is presented, focused on strategies for the synthesis of aminophosphonate and ...
Lemos, A.
core  

A new life for nitrosocarbonyls in pericyclic reactions [PDF]

, 2013
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Memeo, M. G., Paolo Quadrelli
core   +1 more source

Exploring New Chemical Paths in Quantum AI: Preliminary Accomplishments and Future Perspectives

Advanced Quantum Technologies, Volume 9, Issue 2, February 2026.
Two new strategies derived from Chemical AI to promote the advancement of sustainable quantum technologies are presented and discussed. The first strategy relies on the chemical implementation of molecular fuzzy sets, which are quantum mixed states associated with chemical microheterogeneous systems. The second strategy relies on photochromic compounds
Pier Luigi Gentili
wiley   +1 more source

Noninvasive imaging of amyloid‐beta and tau in rodent and nonhuman primate models

VIEW, Volume 7, Issue 1, February 2026.
Imaging of amyloid‐beta plaque and tau accumulation in rodent and nonhuman primate model of Alzheimer's disease. Created in BioRender. Ni R. 2026. https://BioRender.com/a97h5ec Abstract Neurodegenerative diseases are characterized by the aberrant accumulation of protein aggregates.
Ruiqing Ni, Axel Rominger
wiley   +1 more source

Formic Acid as Carbon Monoxide Source: A two-steps Synthesis of 2,5-unsubstituted N-Arylpyrroles from Nitroarenes and Dienes [PDF]

, 2023
Use of Formic Acid as Carbon Monoxide Source for A two-steps Synthesis of 2,5-unsubstituted N-Arylpyrroles from Nitroarenes and Dienes is ...
F. Ferretti, F. Ragaini, M. A. F. Abdellatif, S. Galie   +3 more
core  

Enhancing the Anticancer Efficacy of Polyphenols Through Lipid‐Based and Polymeric Nanoparticle Delivery Systems in Triple‐Negative Breast Cancer (TNBC)

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Breast cancer is the most common cancer among women. Triple‐negative breast cancer (TNBC) lacks hormone receptors and human epidermal growth factor receptor 2 expression and has aggressive behavior and poor prognosis; therefore, it has significant limitations and challenges in its treatment.
Nooshin Goudarzi, Ensiyeh Bahadoran, Masood Alaei, Kimia Taebi, Arian Ashrafzadeh, Arash Keshavarz Shahbaz, Sanaz Keshavarz Shahbaz, Munmun Bardhan   +7 more
wiley   +1 more source

Catalytic Strategies for Amide‐Based Michael Additions: Advances and Perspectives

Journal of Chemistry, Volume 2026, Issue 1, 2026.
The Michael addition is a cornerstone transformation in organic synthesis, enabling efficient C–C and C–heteroatom bond formation. Traditionally, α,β‐unsaturated carbonyl compounds such as enones and esters have dominated as Michael acceptors, whereas α,β‐unsaturated amides remain underutilized due to their strong resonance stabilization and low ...
Muhammad Naufal, Elvira Hermawati, Ace Tatang Hidayat, Dadan Sumiarsa, Ika Wiani Hidayat, Jamaludin Al-Anshori, Tulika Banerjee   +6 more
wiley   +1 more source