Results 111 to 120 of about 15,523 (224)

1,3,4-Oxadiazole as an Anticancer Agent

International Journal For Multidisciplinary Research
The modern era's fastest-growing disease is cancer, it poses a serious threat to people's lives. For the treatment of various cancers, the FDA has approved a number of medications. However, because of the rise in drug toxicity incidents, there is a continual need for the discovery of novel anti-cancer drugs.
Vaishnavi Chopade -, Vinayak Gaware -
openaire   +1 more source

A facile one-pot synthesis of N α-Z/Boc-protected S-linked 1,3,4-oxadiazole tethered peptidomimetics

, 2012
A new class of S-linked 1,3,4-oxadiazole-tethered N α- protected peptidomimetics is designed and synthesized by a reaction of N α-Z/Boc-protected 1,3,4-oxadiazole-2-thiol with α-bromo ester derived from amino acid.
Vasantha, B., Sureshbabu, V.V., Nagendra, G.   +2 more
core   +1 more source

Synthesis, Bioactivities, and Antibacterial Mechanism of 5‑(Thioether)‑N‑phenyl/benzyl-1,3,4-oxadiazole-2-carboxamide/amine Derivatives

1,3,4-Oxadiazole thioethers have shown exciting antibacterial activities; however, the current mechanism of action involving such substances against bacteria is limited to proteomics-mediated protein pathways and differentially expressed gene analysis ...
Zengxue Wu (2629240), Zhongjie Shen (14316779), Hongfu He (2939421), Baoan Song (162306), Awei Zhang (4242703), Ronghua Wang (1834945), Runjiang Song (3091920)   +6 more
core   +1 more source

Síntese de novos mesógenos derivados do heterocíclo imidazo[2,1-b][1,3,4]tiadiazol [PDF]

, 2009
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Curso de Química.A síntese de seis novas moléculas derivadas do heterociclo imidazo[2,1-b][1,3,4]tiadiazol foram realizadas a partir da construções de ...
Ferraz Neto, José
core  

Structure-activity relationship of 1,3,4- oxadiazole compounds [PDF]

, 2017
Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” din Republica MoldovaIntroducere. Derivaţii de oxadiazol se prezintă ca substanţe cu activitate terapeutică vastă: antimicrobială, antiparazitară, antiinflamatoare, anticanceroasă ...
Podgornîi, Ana, Motroi, Luminiţa
core  

A Highly Efficient Diversification of 2‑Amino/Amido-1,3,4-oxadiazole and 1,3,4-Thiadiazole Derivatives via Reagent-Based Cyclization of Thiosemicarbazide Intermediate on Solid-Phase

, 2015
A 2-amino/amido-1,3,4-oxadiazole and 1,3,4-thiadiazole library has been constructed on solid-phase organic synthesis. The key step on this solid-phase synthesis involves the preparation of polymer-bound 2-amino-1,3,4-oxadiazole and 1,3,4-thiadiazole core
Ji-Hye Choe (1463143), Seung-Ju Yang (1463140), Young-Dae Gong (1463149), Aizhan Abdildinova (1463146)   +3 more
core   +1 more source

Cristais líquidos colunares luminescentes com arquiteturas helicoidais [PDF]

, 2011
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2011Neste trabalho, foram projetadas duas famílias inéditas de ácidos carboxílicos com estrutura ...
Vieira, André Alexandre
core  

Revisiting the Formation Mechanism of 1,3,4-Oxadiazole-2(3H)‑ones from Hydrazonyl Chloride and Carbon Dioxide

, 2018
The reaction mechanism for the synthesis of 1,3,4-oxadiazole-2­(3H)-ones from hydrazonyl chloride and CO2 in the presence of CsF/18-crown-6 and toluene, is revisited via density functional theory computations.
Jorge Barroso (3594497), Fernando Murillo (5365844), Gustavo Ávila (5860646), Sudip Pan (1542133), Gabriel Merino (1413124), María A. Fernández-Herrera (1413115), María G. de los Santos (5860643)   +6 more
core   +1 more source

biological Aspects of 1,3,4 -oxadiazole derivatives

, 2014
Heterocyclic compounds analog have attracted wide attention due to their useful biological properties. Among them, 1,3,4-oxadiazoles have exhibiteda wide range of biological properties including anti-bacterial, anti-viral, anti-fungal, anti-cancer, anti ...
S, GNANAVEL, S, KAVITHA, K, KANNAN
core  

Synthesis of some new 2, 5-disubstituted 1,3,4-oxadiazole derivatives and their biological activity

, 2003
900-9042-(Coumarin-3-y l)-5-aryl-1,3,4-oxadiazole derivatives 3-5 have been synthesised by condensing hydrazide 2 of 3-carbethoxycoumarin with various aromatic acids.
Akhtar, M, M. S. Y. Khan, Khan, M S Y, M. Akhtar   +3 more
core   +1 more source