Results 91 to 100 of about 15,523 (224)

Synthesis and evaluation of some new 1,3,4-oxadiazoles bearing thiophene, thiazole, coumarin, pyridine and pyridazine derivatives as antiviral agents

Acta Pharmaceutica, 2019
In an attempt to produce heterocyclic compounds based on 1,3,4-oxadiazole derivatives with potential antiviral activity, synthesis of compound 1 [2-(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)acetonitrile] was performed through the reaction of cyanoacetic
Albratty Mohammed, El-Sharkawy Karam Ahmed, Alhazmi Hassan Ahmed   +2 more
doaj   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

ChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Diazole and triazole derivatives of castor oil extract: synthesis, hypoglycemic effect, antioxidant potential and antimicrobial activity

Grasas y Aceites, 2020
The ricinoleate triglyceride was extracted from castor-oil seeds grown in Algeria and isolated by catalytically methanolyse to methyl ricinoleate.
F. Taieb Brahimi, F. Belkhadem, B. Trari, A. A. Othman   +3 more
doaj   +1 more source

Synthesis, Characterization and Biological activity of 1,3,4- Oxadiazole and 1,3,4- Thiadiazole Derivatives. [PDF]

, 2012
Various substituted 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives have been synthesized by cyclising semicarbazone and thiosemicarbazone in presence of ferric chloride and citric acid to form 2-amino-5-substituted 1,3,4-oxadiazole and 1,3,4 ...
Smylin Ajitha Rani, S
core  

A New Class of Benzo[b]Thiophene‐1,3,4‐Oxadizole Bearing 1,2,4‐Oxadiazoles as Potent Antimicrobial Targets: Synthesis, Biological Evaluation, Docking, DFT and ADMET Studies

ChemistrySelect, Volume 11, Issue 3, 22 January 2026.
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala, Janardan Sannapaneni, Phani Raja Kanuparthy, Venkata Ramana Singamaneni, Tejeswara Rao Allaka, Pilli Veera Venkata Nanda Kishore   +5 more
wiley   +1 more source

Synthesis of Some New Heterocyclic Fused Rings Compounds Based on 5-Aryl-1,3,4-Oxadiazole

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
The work includes synthesis and characterization of some new heterocyclic compounds, as flow: The compound (3) (5-(4-chlorophenyl) -2-hydrazinyl-1,3,4-oxadiazole was synthesized by using two methods; the first method includes the direct reaction between
Zahra Mohammed Abbas, Dhuha Faruq Hussain, Raied Mustafa Shakir   +2 more
doaj  

A New Class of Aromatic Poly(1,3,4-oxadiazole)s and Poly(amide-1,3,4-oxadiazole)s Containing (Naphthalenedioxy)diphenylene Groups [PDF]

, 2002
: Polyhydrazides and poly(amide-hydrazide)s having inherent viscosities of 0.31-1.17 dL g −1 were prepared from two ether-naphthalene-dicarboxylic acids, 4,4'-(1,5-naphthalenedioxy)dibenzoic acid (1,5-NDA) and 4,4'-(2,3-naphthalenedioxy ...
Sheng-Huei Hsiao, Guey-Sheng Liou
core  

Advances in Palladium‐Catalyzed Suzuki–Miyaura Cross‐Coupling Strategies for Heterocyclic Synthesis: Focus on Pyridines, Indoles, and Quinolines

Journal of Chemistry, Volume 2026, Issue 1, 2026.
This review aims to summarize recent developments (2020–2025) in the use of Suzuki–Miyaura cross‐coupling reactions for the synthesis and functionalization of pyridine, indole, and quinoline derivatives—three classes of heterocycles known for their wide‐ranging biological and pharmacological significance.
Shreyas Krishna K., Padmapriya M., Manjunath R., Santosh L. Gaonkar, Munmun Bardhan   +4 more
wiley   +1 more source

Synthesis of a series of novel tetra-tert-butylcalix[4]arene linked to 1,2,4-triazole and 1,3,4-oxadiazole derivatives

Acta Chimica Slovenica, 2016
A series of tetra-tert-butylcalix[4]arene linked to 1,2,4-triazole-5-thiones and 1,3,4-oxadiazole-5-thiones derivatives at lower rim were synthesized by the reaction of 1,2,4-triazole-5-thione and 1,3,4-oxadiazole-5-thione  with 5,11,17,23-tetra-tert ...
Karim Akbari Dilmaghani, Zahra Dono Ghezelbash   +1 more
doaj   +1 more source

Delayed Luminescence in 2‑Methyl-5-(penta(9-carbazolyl)phenyl)-1,3,4-oxadiazole Derivatives

, 2022
2,5-Diphenyl-1,3,4-oxadiazole has been widely used as an acceptor portion of donor–acceptor fluorophores that exhibit thermally activated delayed fluorescence (TADF), but analogous 2-alkyl-5-phenyl-1,3,4-oxadiazoles have been much less widely ...
Ajith Ashokan (13932508), Seth R. Marder (1285467), Xiaoqing Zhang (80417), Stephen Barlow (1401367), Canek Fuentes-Hernandez (1611187), Seyhan Salman (1282398), Matthew W. Cooper (5733482), Yadong Zhang (13685), Bernard Kippelen (1611202)   +8 more
core   +1 more source