Results 81 to 90 of about 15,523 (224)

Síntese de novos cristais líquidos iônicos calamíticos luminescentes [PDF]

, 2010
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Cristais líquidos (CL) têm se tornado um campo cada vez mais atraente devido as aplicações em materiais eletrônicos moleculares da atual ...
SILVA, Danilo Henrique de
core  

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source

Synthesis and antimicrobial evaluation of some 2,5 disubstituted 1,3,4-oxadiazole derivatives

Research in Pharmaceutical Sciences, 2017
1,3,4-oxadiazoles are interesting compounds because of their valuable biological effects such as cytotoxic, antibacterial, antifungal, and anti-tubercular activities.
Elham Jafari, Tahereh Mohammadi, Ali Jahanian-Najafabadi, Farshid Hassanzadeh   +3 more
doaj   +1 more source

1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction [PDF]

Organic Letters, 2019
Easy to perform, functional group tolerant, and short syntheses of the privileged scaffold oxadiazole are highly desired. Here, a metal-free protocol for MCR-based synthesis of 2,5-disubstituted 1,3,4-oxadiazoles via a Ugi-tetrazole/Huisgen sequence was developed.
Qian Wang, Kumchok C. Mgimpatsang, Markella Konstantinidou, Svitlana V. Shishkina, Alexander Dömling   +4 more
openaire   +3 more sources

Bioisosteric replacement of central 1,2,4-oxadiazole ring of high affinity CB2 ligands by regioisomeric 1,3,4-oxadiazole ring

, 2017
It has been reported that bioisosteric replacement of an 1,2,4-oxadiazole ring by an 1,3,4-oxadiazole ring leads to higher polarity, reduced metabolic degradation by human liver microsomes and reduced interaction with hERG channels.
Schepmann, D., Lueg, C., Corinna Lueg, Vries, H. de, Heitman, L.H., Frehland, B., Henk de Vries, Heimann, D., Wunsch, B., Laura H. Heitman, Bastian Frehland, Dominik Heimann, Bernhard Wünsch, Dirk Schepmann   +13 more
core   +1 more source

Chromaticity Control in Light‐Emitting Electrochemical Cells via Thermally Activated Emission in Assemblies of a BN‐Doped Pyrenyl Hydrocarbon

Advanced Functional Materials, Volume 36, Issue 5, 15 January 2026.
The successful color control in light‐emitting electrochemical cells based on highly emissive green‐emitting BN‐doped polyaromatic hydrocarbon with thermally activated NIR emitting assemblies. Abstract This work outlines the synthesis and photo‐/electro‐luminescent behavior of a new C‐shaped BN‐doped benzenoid hydrocarbon using N‐directed borylation in
Luca M. Cavinato, Marco Franceschini, Laura Caputo, Jean‐Christophe Charlier, Marc de Wergifosse, Davide Bonifazi, Rubén D. Costa   +6 more
wiley   +1 more source

Synthesis, Characterization and Effect of bis-1,3,4Oxadiazole Containing Glycine Moiety on the Activity of Some Transferase Enzymes.

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
  We described herein the synthesis of novel bis-1,3,4-oxadiazole containing glycine moiety. N-{5-[5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-yl-sulfanyl]-1,3,4-oxadiazole-2-yl-methyl}-4methoxybenzamide was fully characterized by elemental analysis, FT-IR ...
I. H. R. Tomi, A. H. J. Al-Qaisi, Z. H. J. Al-Qaisi   +2 more
doaj  

Effect of 1,3,4-oxadiazoles on expression of biofilm-associated bap gene in clinical isolates of multidrug-resistant Acinetobacter baumannii

Scientific Reports
The rise of multidrug-resistant (MDR) pathogens, particularly Acinetobacter baumannii, poses a significant threat to global health due to its resistance to multiple antibiotics, biofilm-forming capacity, and associated poor clinical outcomes.
Ali Rahimbakhsh, Mahdi Seyfahmadi, Ali Souldozi, Rakhshan Hakimelahi, Mohammad Yousef Alikhani, Farshid Kafilzadeh   +5 more
doaj   +1 more source

5-(3-Hydroxyphenyl)-1,3,4-oxadiazole-2(3H)-thione hemihydrate

IUCrData, 2019
The title 1,3,4-oxadiazole derivative crystallizes as a hemihydrate, C8H6N2O2S·0.5H2O, with the water molecule located on a twofold rotation axis. The 1,3,4-oxadiazole molecule is essentially planar, the r.m.s. deviation of the non-H atoms being 0.0443 Å.
Surayyo Razzoqovna Razzoqova, Shaxnoza Kadirova, Jamshid Mengnorovich Ashurov, Dilnoza Salamovna Rakhmonova, Abdukhakim Ziyaev, Nusrat Agzamovich Parpiev   +5 more
doaj   +1 more source

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

Archiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová, Šárka Štěpánková, Eva Frýbová, Klára Konečná, Jana Korbielová, Markéta Švarcová, Ondřej Janďourek, Václav Pflégr, Szilvia Bősze, Martin Krátký   +9 more
wiley   +1 more source