Results 61 to 70 of about 2,679 (180)
Copper(II) complexes of chromen-2-one-3-carboxyhydrazide and 2-(chromen-3'-onyl)-5-(aryl)-1,3,4-oxadiazole derivatives have been synthesized. The structural features have been determined from their microanalytical, magnetic susceptibility, molar ...
Glory Mathew +3 more
doaj +1 more source
Materials exist that are useful for gamma scintillation, radiation shielding, neutron‐gamma pulse shape discrimination (PSD), thermal neutron detection, or high refractive index applications. While certain materials have exhibited optimal performance for each of these applications, none achieve multiple functions.
Isabelle Winardi +13 more
wiley +1 more source
In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives
Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah +13 more
wiley +1 more source
Tổng hợp dẫn xuất mang khung kết hợp 1,3,4-oxadiazole/benzimidazole
Các hợp chất dị vòng chứa khung 1,3,4-oxadiazole hay benzimidazole được biết có nhiều hoạt tính sinh học đáng quý như kháng khuẩn, kháng nấm, giảm đau, kháng viêm, kháng virus, kháng ung thư, hạ huyết áp, kháng đái tháo đường và kháng oxy hóa.
Nguyễn Thị Kim Huyền +3 more
doaj +3 more sources
A series of tetra-tert-butylcalix[4]arene linked to 1,2,4-triazole-5-thiones and 1,3,4-oxadiazole-5-thiones derivatives at lower rim were synthesized by the reaction of 1,2,4-triazole-5-thione and 1,3,4-oxadiazole-5-thione with 5,11,17,23-tetra-tert ...
Karim Akbari Dilmaghani +1 more
doaj +1 more source
Background Heteronucleophiles as well as carbanionic reagents can be used to react with α-amido sulfones, thus giving the opportunity to prepare a large array of amino derivatives.
Wang Zhenchao +6 more
doaj +1 more source
A series of novel hybrid molecules containing 1,3,4-oxadiazole and 1,3,4-thiadiazole moieties bearing an ibuprofen moiety were designed, synthesized, and evaluated for their in vitro antibacterial activity against Gram-positive and Gram-negative ...
Rusul K. Fadhel Fadhel +1 more
doaj +1 more source
A novel series of N-phenyl anthranilic acid-based 1,3,4-oxadiazoles were prepared (4a–h) and subjected to anti-inflammatory, analgesic activity and molecular docking studies to target cyclooxygenase-2 enzyme.
Suman Bala +3 more
doaj +1 more source
1,3,4-Thiadiazole and oxadiazole hetetocycles are well-known pharmacophore scaffolds, which possess wide possibility for chemical modification and identified diverse pharmacological potential.
M. I. Lelyukh
doaj +1 more source
Novel S-naproxen- 1,3,4-oxadiazole derivatives were developed and synthesized. via a multi-step route. The synthesis began with conversion of S-(+)-naproxen to an ethyl ester, followed by hydrazide formation and cyclization to yield a 1,3,4-oxadiazole-2-
Farooq Mohammed Hassan +3 more
doaj +1 more source

