Results 61 to 70 of about 18,084 (219)
Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents
1,3,4-Oxadiazoles show various biological activities and have been synthesized from different compounds. 1,3,4-oxadiazole is popularly known for its antimicrobial, anti-inflammatory, pesticidal and antihypertensive activities etc.
Niti Bhardwaj +3 more
doaj +1 more source
Various of 2,5- disubstituted 1,3,4-oxadiazole (Schiff base, ?- lactam and azo) were synthesized from 2,5-di (4,4?-amino-1,3,4-oxadiazole which usequently synth-esized from mixture of 4- amino benzoic acid and hydrazine arch of polyphosphorus acid.
Baghdad Science Journal
doaj +1 more source
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan +2 more
wiley +1 more source
Preparation of a number of heterocyclic compounds derived from benzotrazole [PDF]
In this thesis, a number of heterocyclic compounds with five-memberd , such as substituted oxadiazole , thiadiazole , pyrazole , iso andoline-1,3-dione , also the preparation of pyrroline and pyrrolidine compounds . The ester compound (1) was
Mohamed Mohamed, Ahmed Ahmed
doaj +1 more source
ABSTRACT Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to target the catalytic ...
Nader R. Albujuq +6 more
wiley +1 more source
Síntese de duas novas séries de compostos com estrutura discótica contendo derivados do ácido gálico [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemática. Programa de Pós-Graduação em QuímicaNesta dissertação, são descritas a síntese e as propriedades térmicas de duas séries de compostos com estrutura ...
Frizon, Tiago Elias Allievi
core
A novel simple 1,3,4-oxadiazole-2-carbohydrazide was reported to discover low-cost and versatile antifungal agents. Bioassay results suggested that a majority of the designed compounds were extremely bioactive against four types of fungi and two kinds of
Jian-Jun Zhu +15 more
core +1 more source
Isosteric Substitution Enables Rational Design of Two‐Dimensional Energetic Crystals
Isosteric substitution transforms a classical nitro–amine motif into two‐dimensional aminofurazans with performance beyond TATB. ABSTRACT Two‐dimensional (2D) energetic crystals dissipate mechanical insult via interlayer slip, yet their molecular design space remains narrow.
Linyuan Wen +6 more
wiley +1 more source
Synthesis of 2-Isobutyl, 2-Isobutyl-5-aryl and 2-Isobutyl-5-thiol-1,3,4-Oxadiazoles [PDF]
In this paper the synthesis of some substituted 1,3,4-oxadiazoles from isobutyric acid was studied. The isobutyric acid was converted into the corresponding ethyl ester, which then treated with hydrazine hydrate in ethanol to give the acid hydrazide. The
Hadil S. Aziz, Khalid M. Daoud
doaj +1 more source
New phosphino tricarbonylrhenium(I) complexes have efficient red emission in the aggregate and solid states. The good photostability and the vast possibilities of chemical modifications make these Re‐based complexes the starting point of a new generation of red emitters with aggregation‐induced phosphorescence emission (AIPE) characteristics.
Valentine Guilbaud +8 more
wiley +1 more source

