Results 61 to 70 of about 2,679 (180)

Synthesis, Spectral Characterization and Biocidal Studies of Copper(II) Complexes of Chromen-2-one-3-carboxy Hydrazide and 2-(Chromen-3'-onyl)-5-(aryl)-1,3,4-oxadiazole Derivatives

open access: yesE-Journal of Chemistry, 2011
Copper(II) complexes of chromen-2-one-3-carboxyhydrazide and 2-(chromen-3'-onyl)-5-(aryl)-1,3,4-oxadiazole derivatives have been synthesized. The structural features have been determined from their microanalytical, magnetic susceptibility, molar ...
Glory Mathew   +3 more
doaj   +1 more source

Multipurpose Transparent Nanocomposites for Gamma Spectroscopy, Pulse Shape Discrimination, Thermal Neutron Detection, Radiation Shielding, and High Refractive Index Applications

open access: yesAdvanced Functional Materials, Volume 36, Issue 28, 7 April 2026.
Materials exist that are useful for gamma scintillation, radiation shielding, neutron‐gamma pulse shape discrimination (PSD), thermal neutron detection, or high refractive index applications. While certain materials have exhibited optimal performance for each of these applications, none achieve multiple functions.
Isabelle Winardi   +13 more
wiley   +1 more source

In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah   +13 more
wiley   +1 more source

Tổng hợp dẫn xuất mang khung kết hợp 1,3,4-oxadiazole/benzimidazole

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2019
Các hợp chất dị vòng chứa khung 1,3,4-oxadiazole hay benzimidazole được biết có nhiều hoạt tính sinh học đáng quý như kháng khuẩn, kháng nấm, giảm đau, kháng viêm, kháng virus, kháng ung thư, hạ huyết áp, kháng đái tháo đường và kháng oxy hóa.
Nguyễn Thị Kim Huyền   +3 more
doaj   +3 more sources

Synthesis of a series of novel tetra-tert-butylcalix[4]arene linked to 1,2,4-triazole and 1,3,4-oxadiazole derivatives

open access: yesActa Chimica Slovenica, 2016
A series of tetra-tert-butylcalix[4]arene linked to 1,2,4-triazole-5-thiones and 1,3,4-oxadiazole-5-thiones derivatives at lower rim were synthesized by the reaction of 1,2,4-triazole-5-thione and 1,3,4-oxadiazole-5-thione  with 5,11,17,23-tetra-tert ...
Karim Akbari Dilmaghani   +1 more
doaj   +1 more source

Inorganic base-catalyzed formation of antivirally active N-substituted benzamides from α-amido sulfones and N-nucleophile

open access: yesChemistry Central Journal, 2011
Background Heteronucleophiles as well as carbanionic reagents can be used to react with α-amido sulfones, thus giving the opportunity to prepare a large array of amino derivatives.
Wang Zhenchao   +6 more
doaj   +1 more source

Synthesis and Antibacterial Activity of New Hybrid Molecules Containing 1,3,4-Thiadiazole and 1,3,4-Oxadiazole Bearing Ibuprofen Moiety

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences
A series of novel hybrid molecules containing 1,3,4-oxadiazole and 1,3,4-thiadiazole moieties bearing an ibuprofen moiety were designed, synthesized, and evaluated for their in vitro antibacterial activity against Gram-positive and Gram-negative ...
Rusul K. Fadhel Fadhel   +1 more
doaj   +1 more source

Anti-Inflammatory, Analgesic Evaluation and Molecular Docking Studies of N-Phenyl Anthranilic Acid-Based 1,3,4-Oxadiazole Analogues

open access: yesJournal of Chemistry, 2013
A novel series of N-phenyl anthranilic acid-based 1,3,4-oxadiazoles were prepared (4a–h) and subjected to anti-inflammatory, analgesic activity and molecular docking studies to target cyclooxygenase-2 enzyme.
Suman Bala   +3 more
doaj   +1 more source

Biological activity of heterocyclic systems based on functionally substituted 1,3,4-thia(oxa)diazoles (a review)

open access: yesФармацевтичний журнал, 2019
1,3,4-Thiadiazole and oxadiazole hetetocycles are well-known pharmacophore scaffolds, which possess wide possibility for chemical modification and identified diverse pharmacological potential.
M. I. Lelyukh
doaj   +1 more source

Synthesis, Characterization, and Cytotoxicity Assessment of Novel S- Naproxen- based 1,3,4-Oxadiazole Thioethers against A549 Lung Carcinoma

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences
Novel S-naproxen- 1,3,4-oxadiazole derivatives were developed and synthesized. via a multi-step route. The synthesis began with conversion of S-(+)-naproxen to an ethyl ester, followed by hydrazide formation and cyclization to yield a 1,3,4-oxadiazole-2-
Farooq Mohammed Hassan   +3 more
doaj   +1 more source

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