Results 61 to 70 of about 18,084 (219)

Syntheses, Evaluation and Characterization of Some 1, 3, 4-Oxadiazoles as Antimicrobial Agents

open access: yesE-Journal of Chemistry, 2009
1,3,4-Oxadiazoles show various biological activities and have been synthesized from different compounds. 1,3,4-oxadiazole is popularly known for its antimicrobial, anti-inflammatory, pesticidal and antihypertensive activities etc.
Niti Bhardwaj   +3 more
doaj   +1 more source

Synthesis and Characterization of some New 1,3,4-Oxadiazole derivatives based on 4-amino benzoic acid

open access: yesمجلة بغداد للعلوم, 2016
Various of 2,5- disubstituted 1,3,4-oxadiazole (Schiff base, ?- lactam and azo) were synthesized from 2,5-di (4,4?-amino-1,3,4-oxadiazole which usequently synth-esized from mixture of 4- amino benzoic acid and hydrazine arch of polyphosphorus acid.
Baghdad Science Journal
doaj   +1 more source

Structural Modifications of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery

open access: yesArchiv der Pharmazie, Volume 359, Issue 8, August 2026.
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan   +2 more
wiley   +1 more source

Preparation of a number of heterocyclic compounds derived from benzotrazole [PDF]

open access: yesمجلة التربية والعلم, 2013
In this thesis, a number of heterocyclic compounds with  five-memberd  , such as substituted oxadiazole  , thiadiazole , pyrazole , iso andoline-1,3-dione , also the preparation of  pyrroline and pyrrolidine compounds .      The  ester  compound  (1) was
Mohamed Mohamed, Ahmed Ahmed
doaj   +1 more source

Structure‐Based Design, Synthesis, and Biological Evaluation of Oxadiazole–Morpholine Hybrids as Potent PARP‐1 Inhibitors Inducing Apoptosis in Breast Cancer Cells

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to target the catalytic ...
Nader R. Albujuq   +6 more
wiley   +1 more source

Síntese de duas novas séries de compostos com estrutura discótica contendo derivados do ácido gálico [PDF]

open access: yes, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemática. Programa de Pós-Graduação em QuímicaNesta dissertação, são descritas a síntese e as propriedades térmicas de duas séries de compostos com estrutura ...
Frizon, Tiago Elias Allievi
core  

Novel 1,3,4-Oxadiazole-2-carbohydrazides as Prospective Agricultural Antifungal Agents Potentially Targeting Succinate Dehydrogenase

open access: yes, 2019
A novel simple 1,3,4-oxadiazole-2-carbohydrazide was reported to discover low-cost and versatile antifungal agents. Bioassay results suggested that a majority of the designed compounds were extremely bioactive against four types of fungi and two kinds of
Jian-Jun Zhu   +15 more
core   +1 more source

Isosteric Substitution Enables Rational Design of Two‐Dimensional Energetic Crystals

open access: yesAdvanced Science, Volume 13, Issue 39, 13 July 2026.
Isosteric substitution transforms a classical nitro–amine motif into two‐dimensional aminofurazans with performance beyond TATB. ABSTRACT Two‐dimensional (2D) energetic crystals dissipate mechanical insult via interlayer slip, yet their molecular design space remains narrow.
Linyuan Wen   +6 more
wiley   +1 more source

Synthesis of 2-Isobutyl, 2-Isobutyl-5-aryl and 2-Isobutyl-5-thiol-1,3,4-Oxadiazoles [PDF]

open access: yesمجلة التربية والعلم, 2007
In this paper the synthesis of some substituted 1,3,4-oxadiazoles from isobutyric acid was studied. The isobutyric acid was converted into the corresponding ethyl ester, which then treated with hydrazine hydrate in ethanol to give the acid hydrazide. The
Hadil S. Aziz, Khalid M. Daoud
doaj   +1 more source

The Solid‐State Emission of AIPE‐Active Tricarbonylrhenium(I) Complexes Shifts to the Red: The Unexpected Performance of Triphenylphosphine Derivatives

open access: yesAggregate, Volume 7, Issue 7, July 2026.
New phosphino tricarbonylrhenium(I) complexes have efficient red emission in the aggregate and solid states. The good photostability and the vast possibilities of chemical modifications make these Re‐based complexes the starting point of a new generation of red emitters with aggregation‐induced phosphorescence emission (AIPE) characteristics.
Valentine Guilbaud   +8 more
wiley   +1 more source

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