Results 191 to 200 of about 15,523 (224)

1,3,4-Oxadiazoles as Anticancer Agents: A Review

Recent Patents on Anti-Cancer Drug Discovery
Abstract: Among the deadliest diseases, cancer is characterized by tumors or an increased number of a specific type of cell because of uncontrolled divisions during mitosis. Researchers in the current era concentrated on the development of highly selective anticancer medications due to the substantial toxicities of conventional cytotoxic drugs ...
Greesh Kumar, Rajnish Kumar, Avijit Mazumder, null Salahuddin, Upendra Kumar   +4 more
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Perfluoro-bis-1,3,4 oxadiazoles

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1965
1. The hydrazides of perfluorodicarboxylic acids of the general formula NH2NHCO(CF2)nCONHNH2 (n= 3,4,8,12) were produced by the action of hydrazine hydrate on the diethyl esters of the perfluorodicarboxylic acids in alcohol solutions. 2.
M. P. Krasuskaya, D. P. Del'tsova, I. L. Knunyants   +2 more
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Aliphatic poly‐1,3,4‐oxadiazoles

Journal of Polymer Science Part A: General Papers, 1965
AbstractThree high molecular weight aliphatic polyoxadiazoles have been prepared by a new route from equimolar amounts of a diphenyl ester of dicarboxylic acid and an anhydrous hydrazine (or a dihydrazide). The resulting polymers have been characterized by microanalysis, intrinsic viscosity, x‐ray diffraction patterns, infrared absorption spectra, and ...
Terunobu Unishi, Masaki Hasegawa
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Anti-inflammatory Activity of Substituted 1,3,4-Oxadiazoles

Journal of Pharmaceutical Sciences, 1994
Various 5-[[(acetamidophen-4-yl)oxy]methyl]-2-(p-substituted phenylamino)-1,3,4-oxadiazoles (4a-4d) were synthesized by cyclization of the corresponding N1-[[(acetamidophen-4-yl)oxy]acetyl]- N4-(p-substituted phenylamino)-3-thiosemicarbazides (3a-3d). All four of the thiosemicarbazides [250 mg/kg, orally (p.o.)] and the corresponding oxadiazoles (250 ...
L V, Nargund, G R, Reddy, V, Hariprasad
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ChemInform Abstract: Synthesis and Antioxidant Activity of Styrylsulfonylmethyl 1,3,4‐Oxadiazoles, Pyrazolyl/Isoxazolyl‐1,3,4‐oxadiazoles.

ChemInform, 2014
AbstractCompound (IIIb) is found to exhibit slightly higher antioxidant activity than the standard ascorbic acid.
Guda Mallikarjuna Reddy, Akkarapalli Muralikrishna, Venkatapuram Padmavathi, Adivireddy Padmaja, Thandaiah Krishna Tilak, Chippada Appa Rao   +5 more
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THE CHEMISTRY OF 1,3,4-OXADIAZOLE DERIVATIVES

Russian Chemical Reviews, 1964
CONTENTS I. Introduction 508 II. Preparation of mono-substituted 1,3,4-oxadiazoles 508 III. Preparation of symmetrical 2,5-substituted 1,3,4-oxadiazoles 508 IV. Preparation of asymmetrical 2,5-substituted 1,3,4-oxadiazoles 509 V. Preparation of poly-1,3,4-oxadiazoles 511 VI.
E P Nesynov, A P Grekov
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Pushing the Limits of Oxygen Balance in 1,3,4-Oxadiazoles

Journal of the American Chemical Society, 2017
Gem-trinitromethyl groups were introduced into a 1,3,4-oxadiazole ring to give the first example of a bifunctionalized single five-membered ring with six nitro groups. 2,5-Bis(trinitromethyl)-1,3,4-oxadiazole (12) has a high calculated crystal density of 2.007 g cm-3 at 150 K (1.941 g cm-3 at 293 K) and a very high positive oxygen balance (39.12 ...
Qiong Yu, Ping Yin, Jiaheng Zhang, Chunlin He, Gregory H. Imler, Damon A. Parrish, Jean’ne M. Shreeve   +6 more
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Anti-inflammatory Activity of Substituted 1,3,4-Oxadiazoles

Journal of Pharmaceutical Sciences, 1989
Various 2-(4-biphenoxymethyl)-5-arylamino-1,3,4-oxadiazoles were synthesized by cyclization of the corresponding 1-(4-biphenoxyacetyl)-4-substituted thiosemicarbazides. These compounds were characterized by their elemental analyses and infrared, mass, and nuclear magnetic resonance spectral data.
K, Raman, S S, Parmar, S K, Salzman
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General Synthesis of Tetrasubstituted Alkenyl‐1,3,4‐oxadiazoles.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Clint A. James, Brigitte Poirier, Christiane Grisé, Alain Martel, Edward H. Ruediger   +4 more
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Trimethylsilyl-1,3,4-oxadiazoles—new useful synthons for the synthesis of various 2,5-disubstituted-1,3,4-oxadiazoles

Tetrahedron, 2008
Abstract The reactivity of 2-aryl-5-trimethylsilyl-1,3,4-oxadiazoles toward different types of electrophiles was investigated. These silanes readily react with chlorine, bromine, aliphatic acyl chlorides, 2-nitrobenzenesulfenyl chloride, and some reactive isocyanates affording the corresponding substituted 1,3,4-oxadiazoles.
Evgenij V. Zarudnitskii, Igor I. Pervak, Anatolij S. Merkulov, Aleksandr A. Yurchenko, Andrej A. Tolmachev   +4 more
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