Results 121 to 130 of about 37,093 (255)

Rapid Assembly of Pyrrole-Ligated 1,3,4-Oxadiazoles and Excellent Antibacterial Activity of Iodophenol Substituents. [PDF]

Molecules, 2023
Kim H, Gu L, Yeo H, Choi U, Lee CR, Yu H, Koo S.   +6 more
europepmc   +1 more source

1,3,4-Oxadiazole as an Anticancer Agent

International Journal For Multidisciplinary Research
The modern era's fastest-growing disease is cancer, it poses a serious threat to people's lives. For the treatment of various cancers, the FDA has approved a number of medications. However, because of the rise in drug toxicity incidents, there is a continual need for the discovery of novel anti-cancer drugs.
Vaishnavi Chopade -, Vinayak Gaware -
openaire   +1 more source

Biological evaluation of 1,3,4-oxadiazoles bis-substitute derivatives as potential anticancer agents [PDF]

, 2015
Cancer is a major health problem and causes substantial morbidity and mortality worldwide.In order to identify new potent antitumor agents with good specificity and low toxicity, a series of 12 new 1,3,4-oxadiazole bis-substitute molecules were tested on
NIEDDU, Valentina
core  

An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches. [PDF]

Biomedicines, 2023
Irfan A, Faisal S, Ahmad S, Saif MJ, Zahoor AF, Khan SG, Javid J, Al-Hussain SA, Muhammed MT, Zaki MEA.   +9 more
europepmc   +1 more source

Modular and Computational Access to Innocuous Multistep Metal-Free Synthesis of 1,3,4-Oxadiazoles as Enzyme Inhibitors. [PDF]

ACS Omega, 2023
Umair M, Rehman AU, Abbasi MA, Siddiqui SZ, Iqbal J, Khalid H, Rasool S, Khan SU, Zafar F.   +8 more
europepmc   +1 more source

Novel Macrocyclic 1,3,4-Oxadiazoles as CFTR Modulators for Treating Cystic Fibrosis. [PDF]

ACS Med Chem Lett, 2022
Sabnis RW.
europepmc   +1 more source

Design, Synthesis and Bioactivity Evaluation of Novel 2-(pyrazol-4-yl)-1,3,4-oxadiazoles Containing an Imidazole Fragment as Antibacterial Agents. [PDF]

Molecules, 2023
Liu H, Yang S, Li T, Ma S, Wang P, Wang G, Su S, Ding Y, Yang L, Zhou X, Yang S.   +10 more
europepmc   +1 more source

Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity. [PDF]

J Biol Chem, 2023
Cellupica E, Caprini G, Cordella P, Cukier C, Fossati G, Marchini M, Rocchio I, Sandrone G, Vanoni MA, Vergani B, Źrubek K, Stevenazzi A, Steinkühler C.   +12 more
europepmc   +1 more source

Therapeutic potential of 1,3,4-oxadiazoles as potential lead compounds for the treatment of Alzheimer's disease. [PDF]

RSC Adv, 2023
Naseem S, Temirak A, Imran A, Jalil S, Fatima S, Taslimi P, Iqbal J, Tasleem M, Tahir MN, Shafiq Z.   +9 more
europepmc   +1 more source

Synthesis of 2-aryl-5-(arylsulfonyl)-1,3,4-oxadiazoles as potent antibacterial and antioxidant agents. [PDF]

Turk J Chem, 2022
Murthy BSN, Talari S, Kola AE, Chalapaka B.   +3 more
europepmc   +1 more source