Preparation of 2,5-Diaryl-1,3,4-Oxadiazoles
This report regards the research conducted in the synthesis of 2,5-disubstituted-1,3,4-oxadiazoles as potential insecticides which are closely related to the known insecticide DOWCO 416R, 2,5-bis(2,4-dichlorophenyl)-1,3,4-oxadiazole.
Dobe, Joachim D.
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1,3,4-Oxadiazole as an Anticancer Agent
The modern era's fastest-growing disease is cancer, it poses a serious threat to people's lives. For the treatment of various cancers, the FDA has approved a number of medications. However, because of the rise in drug toxicity incidents, there is a continual need for the discovery of novel anti-cancer drugs.
Vaishnavi Chopade -, Vinayak Gaware -
openaire +1 more source
Rapid Assembly of Pyrrole-Ligated 1,3,4-Oxadiazoles and Excellent Antibacterial Activity of Iodophenol Substituents. [PDF]
Kim H +6 more
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Synthesis, characterization and antioxidant activity of 1,3,4-oxadiazoles incorporating an indole moiety [PDF]
In this project, an indole ester, carboxyl hydrazide and four new 1,3,4-oxadiazoles derivatives have been successfully synthesized and characterized. The four new 1,3,4-oxadiazoles derivatives were synthesized by the reaction of carboxyl hydrazide and ...
Chong, Jien Lee
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Post-Graduate Department of Chemistry, University of Jammu, Jammu-180 004 Manuscript received 20 May 1987, revised 15 November 1988, accepted 14 December 1988 Some 2-(\(\beta\)-arylethyl)-5-phenylamino-1,3,4-oxadiazoles, 2-(\(\beta\)-arylethyl)-5 ...
T. C. LANGER +2 more
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An efficient synthesis of 2,5-diaryl-1,3,4-oxadiazoles [PDF]
Synthesis of 2,5-diaryl-1,3,4-oxadiazoles (2a-e) by the oxidation of acyl hydrazones (1a-e) with chloramine-T trihydrate has been achieved.
Rai, K. M. Lokanatha, Linganna, N.
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International audienceWe report herein the synthesis of 2,5-diaryl-1,3,4-oxadiazoles containing both electron-donating and withdrawing substituents as well as bis- and tris-2,5-disubstituted-1,3,4-oxadiazoles containing electron-donating substituents ...
Gautier, Arnaud +5 more
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An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches. [PDF]
Irfan A +9 more
europepmc +1 more source
Novel Macrocyclic 1,3,4-Oxadiazoles as CFTR Modulators for Treating Cystic Fibrosis. [PDF]
Sabnis RW.
europepmc +1 more source
Superior Reactivity of Thiosemicarbazides in the Synthesis of 2-Amino-1,3,4-oxadiazoles
A facile and general protocol for the preparation of 2-amino-1,3,4-oxadiazoles is reported. This method relies on a tosyl chloride/pyridine-mediated cyclization of a thiosemicarbazide, which is readily prepared by acylation of a given hydrazide with the ...
Ian W. Davies (1436695) +3 more
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