Results 81 to 90 of about 12,947 (217)

In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives

open access: yesChemistryOpen, Volume 15, Issue 4, April 2026.
Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah   +13 more
wiley   +1 more source

Síntese de cristais líquidos funcionalizados contendo o heterociclo 1,3,4-oxadiazol [PDF]

open access: yes, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Neste trabalho são descritas a síntese, a caracterização e os estudos das propriedades ópticas,
Westphal, Eduard
core  

Microwave Irradiation Promoted Reactions of Orthoesters with Carboxylic Acid Hydrazides. Preparation of 1,3,4-Oxadiazoles [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 1997
Rapid and highly efficient synthesis of 2- or 2,5-substituted 1,3,4-oxadiazoles by the condensation of aryl carboxylic acid hydrazides and orthoesters can be achieved under microwave irradiation using an unmodified commercial over in unsealed vessels.
Mohammad Sadegh Khajavi   +2 more
doaj  

Heterocycles from saccharide hydrazones. Part I. Saccharide 1,3,4-oxadiazoles

open access: yes, 1972
Oxidation, with iodine-mercuric oxide, of acetylated saccharide aroylhydrazones and of aromatic aldehyde hydrazones yields 5-aryl-2-(polyacetoxyalkyl)-1,3,4-oxadiazoles and 2,5-diaryl-1,3,4-oxadiazoles, respectively.
H. El Khadem   +5 more
core   +1 more source

Intramolecular Diels−Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles

open access: yes, 2016
Full details of a systematic exploration of the intramolecular [4 + 2]/[3 + 2] cycloaddition cascade of 1,3,4-oxadiazoles are disclosed in which the scope and utility of the reaction are ...
James R. Fuchs (143921)   +6 more
core   +2 more sources

Síntese e caracterização de cristais liquidos tipo bastão de hockey [PDF]

open access: yes, 2005
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Este trabalho tem como objetivo geral a síntese de cristais líquidos termotrópicos, com forma semelhante a bastões de hockey contendo o ...
VIEIRA , André Alexandre
core  

Synthesis, antibacterial activity and in silico study of new bis(1,3,4-oxadiazoles)

open access: yes, 2022
In the current study, new bis(2,5-disubstituted 1,3,4-oxadiazoles) linked to aliphatic cores were efficiently prepared. For this purpose, the appropriate bis(aldehydes) and benzohydrazides were reacted to produce the corresponding bis(N-benzoylhydrazones)
Ahmed E. M. Mekky (6618713)   +2 more
core   +1 more source

Síntese de novos cristais líquidos iônicos calamíticos luminescentes [PDF]

open access: yes, 2010
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Cristais líquidos (CL) têm se tornado um campo cada vez mais atraente devido as aplicações em materiais eletrônicos moleculares da atual ...
SILVA, Danilo Henrique de
core  

Palladium-Catalyzed Cross-Coupling of 1,3,4-Oxadiazoles and Styrenes: An Efficient Method to Synthesize 2-Alkenyl-1,3,4- Oxadiazoles§

open access: yes, 2017
2-Alkenyl-1,3,4-oxadiazole derivatives have been prepared by cross-coupling of 1,3,4-oxadiazoles with styrenes by using palladium(II) trifluoroacetate [Pd(TFA)2] as a catalyst, 1,10-phenanthroline as a ligand, silver trifluoroacetate as an oxidant, and ...
Biswanath Das, N. Salvanna, P. Reddy
core   +1 more source

Synthesis and fluorescence studies of porphyrin appended 1,3,4-oxadiazoles

open access: yes, 2010
A modular synthetic approach for preparing a family of porphyrin appended 1,3,4-oxadiazoles 9 is described. The porphyrin hydrazides are reacted with aryl aldehydes in presence of Yb(OTf)3 as catalyst to give porphyrin hydrazones 8 which are then ...
Dalip Kumar   +5 more
core   +1 more source

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