Results 91 to 100 of about 12,947 (217)

Synthesis, Characterization and study biologicalactivity of several 1-cyclopentene-1,2-dicarboxylimidyl Containing oxadiazole and Benzothiazole

مجلة بغداد للعلوم, 2014
In this work involved prepared of several new 1-cyclopentene-1,2-dicarboxylimide linked to oxadiazole and benzothiazole moiety were synthesized by two steps: The first step 2-amino-substituted-1,3,4-oxadiazoles and substituted-2-aminobenzothiazole were ...
Baghdad Science Journal
doaj   +1 more source

Synthesis, characterization and antioxidant activity of 1,3,4-oxadiazoles bearing an indole ring [PDF]

, 2019
1,3,4-oxadiazoles have been widely studied by many researchers in various fields. Due to its heterocyclic structure, 1,3,4-oxadiazoles possess of many biological and pharmacological activities such as antibacterial, anticancer, antiinflammatory ...
Kong, Kian Liang
core  

Improved Protocol Toward 1,3,4-Oxadiazole-2(3H)-thiones and Scale-up Synthesis in the Presence of SDS as a Micelle Promoted Catalyst

Acta Chimica Slovenica, 2015
Convenient procedure for in situ cyclization of hydrazinecarbodithioate potassium salts to 1,3,4-oxadiazole-2(3H)-thiones under normal phase micellar media catalysis promoted by sodium dodecyl sulfate (SDS) as an anionic surfactant is reported.
Ayhan YILDIRIM
doaj   +1 more source

Anion-Driven C–F Bond Activation of Trifluoromethyl N‑Aryl Hydrazones: Application to the Synthesis of 1,3,4-Oxadiazoles

The CF3 group attached to N-aryl hydrazone could be activated upon treatment with a suitable base, thus serving as an excellent C1 unit for the assembly of a series of 1,3,4-oxadiazoles by reaction with hydrazides.
Fangyi Li (1566442), Qijie Zou (11675008), Guangwei Yin (2028787), Wei Zhang (405), Yongzhi He (517245), Haoyue Wang (13138179)   +5 more
core   +1 more source

Molecular Structure, Matrix-Isolation IR Spectrum and UV-Induced Transformations of 2-Amino-5-(4-Methoxyphenyl)-1,3,4-Oxadiazole

Molecules
The photochemistry of 1,3,4-oxadiazoles remains poorly understood, despite their recognized importance in medicinal chemistry and materials science. In this work, we report a detailed matrix-isolation study of 2-amino-5-(4-methoxyphenyl)-1,3,4-oxadiazole,
İsa Sıdır, Susy Lopes, Rui Fausto, A. J. Lopes Jesus   +3 more
doaj   +1 more source

Synthesis, Reactions and Antioxidant Activity of 5-(3', 4'-dihydroxy-tetrahydrofuran-2'-yl)-2-methyl-3-carbohydrazide [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
In this manuscript, we describe the synthesis of the carbohydrazide 2. Acid-catalyzed condensation with several carbonyl compounds to afford the corresponding carbohydrazide derivatives 3-12.
Mohamed El Sadek, Samir Ahmed Magd, Seham Yassen Hassan, Mohamed A. Mostafa, Galile Yacouat   +4 more
doaj  

Synthetic Approaches to 1,3,4-Oxadiazole-Containing Boronic Derivatives

Applied Sciences
1,3,4-Oxadiazoles containing boronic acid moieties are promising as a highly versatile class of compounds with significant utility across various scientific domains.
Barbara Wołek, Agnieszka Kudelko
doaj   +1 more source

Reaction of 2,5-Disubstituted-1,3,4-oxadiazoles

, 1985
Some 5-aryl-2-mercapto-1,3,4-oxadiazole (I) reacted with maleic anhydride, maleic acid and p-benzoquinone affording 2-(5-aryl- -1,3,4-oxadiazol-2-ylthio)succinic anhydrides (II), 2-(5-aryl-1,3,4- -oxadiazol-2-ylthio)succinic acids (III) and 2-(2,5 ...
El-Barbary, Ahmed A., Ahmed A. El-Barbary   +1 more
core  

Ring transformations of heterocycles. Part 1. Transformation of 4‐amino‐Δ2‐1,2,4‐oxadiazolines into 1,3,4‐oxadiazoles

, 1991
3‐Aryl‐4‐amino‐δ2‐1,2,4‐oxadiazolines 3 and their N‐chloroacetyl derivatives 4, upon treatment with chloroacetic anhydride in refluxing toluene, afford 2‐chloromethyl‐5‐aryl‐1,3,4‐oxadiazoles 5, suggesting the conversion sequence 3 → 4 → 5.
Woydt, M, El‐abadelah, MM, Rademacher, Paul, Awadallah, Adel M., Nazer, MZ, Hussein, AQ   +5 more
core   +1 more source

Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6. [PDF]

J Med Chem, 2023
König B, Watson PR, Reßing N, Cragin AD, Schäker-Hübner L, Christianson DW, Hansen FK.   +6 more
europepmc   +1 more source