Results 71 to 80 of about 12,947 (217)

5-Phenyl-1,3,4-oxadiazol-2-amine [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title complex, C(8)H(7)N(3)O, the C-O [1.369 (2) and 1.364 (3) Å] and C=N [1.285 (3) and 1.289 (3) Å] bond lengths in the oxadiazole ring are each almost identical within systematic errors, although different substituents are attached to the ring. The phenyl ring is inclined to the planar oxadiazole ring [r.m.s. deviation 0.002 Å] by 13.42 (18)°.
Man-Man Song, Kong-Li Wu, Lin Zhu, Juan Zheng, Yan Xu   +4 more
openaire   +3 more sources

Efficient Phosphonium-Mediated Synthesis of 2-Amino-1,3,4-oxadiazoles

, 2016
We present an efficient, room temperature procedure for the preparation of 2-amino-1,3,4-oxadiazoles. Oxadiazol-2-ones can be activated for SNAr substitution using phosphonium reagents (e.g., BOP).
Zhao-Kui Wan (2004907), Christopher G. Levins (2074954)   +1 more
core   +2 more sources

Excimer Formation in Aqueous Solutions of Hosts and Application in Synthesis

ChemPhotoChem, Volume 10, Issue 4, April 2026.
This review explores how host‐mediated excimer formation in water, facilitated by supramolecular confinement enhances photochemical synthesis. By improving solubility, local concentrations, and orientational control, these systems can boost efficiency and selectivity in reactions like photocycloadditions and photodimerizations.
Doğan Akbulut, Florian Friedmann, Gianna Pölderl, Line Næsborg   +3 more
wiley   +1 more source

Synthesis of Dendrimers Containing 1,3,4-Oxadiazoles

, 2016
Synthesis of Dendrimers Containing 1,3,4 ...
Wim Dehaen (496141), Bert Verheyde (2988930)   +1 more
core   +1 more source

Anti-Inflammatory, Analgesic Evaluation and Molecular Docking Studies of N-Phenyl Anthranilic Acid-Based 1,3,4-Oxadiazole Analogues

Journal of Chemistry, 2013
A novel series of N-phenyl anthranilic acid-based 1,3,4-oxadiazoles were prepared (4a–h) and subjected to anti-inflammatory, analgesic activity and molecular docking studies to target cyclooxygenase-2 enzyme.
Suman Bala, Sunil Kamboj, Vipin Saini, D. N. Prasad   +3 more
doaj   +1 more source

Structure‐Guided Optimization and Biological Validation of 1,3,4‐Thiadiazole‐Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel, Fikriye Ozgencil, Filiz Bakar‐Ates, Habibe Beyza Gunindi, Alberto Massarotti, Erva Ozkan, Selen Gozde Kaya, Mahmut Gozelle, Yesim Ozkan, Gokcen Eren   +9 more
wiley   +1 more source

Hypervalent iodine(V) mediated mild and convenient synthesis of substituted 2-amino-1,3,4-oxadiazoles [PDF]

, 2012
A simple protocol for the synthesis of 2-amino-1,3,4-oxadiazoles starting from the corresponding acylhydrazides by cyclodesulfurization of intermediate acylthiosemicarbazides mediated by o-iodoxybenzoic acid in good yields has been described.
Prabhu, G., Sureshbabu, V.V.
core   +1 more source

SYNTHESIS AND CHARACTERIZATION OF [(5-MERCAPTO-1,3,4-OXADIAZOL-2-YL)ARYL]-3,5-DIARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOTHIOAMIDES [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2011
The synthesis and characterization of [(5-mercapto-1,3,4-oxadiazol-2-yl)aryl]-3,5-diaryl-4,5-dihydro-1Hpyrazole-1-carbothioamides - derivatives of pyrazolines and 5-[4(3)-isothiocyanatophenyl]-2-thio-1,3,4-oxadiazoles were realized.
Zinaida Ribkovskaia, Serghei Pogrebnoi, Alic Barba, Fliur Macaev   +3 more
doaj  

Synthesis, Characterization, and Biological Evaluation of Aliphatic‐Substituted Benzimidazole Derivatives: Induction of Apoptosis, Cell Cycle Arrest, and Molecular Docking in Breast Cancer Cells

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT A new series of aliphatic‐substituted benzimidazole derivatives was synthesized and structurally characterized to evaluate their potential anticancer activity. Among the synthesized compounds, compound 4 exhibited the most potent cytotoxic effects against MCF‐7 and MDA‐MB‐231 breast cancer cell lines, with IC₅₀ values comparable to those of ...
Murat Keser, Çisil Çamlı Pulat, Harika Atmaca, Hakan Akgün, Canan Albay, Emre Menteşe, Hakan Bektaş, Suleyman Ilhan   +7 more
wiley   +1 more source

Síntese de duas novas séries de compostos com estrutura discótica contendo derivados do ácido gálico [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemática. Programa de Pós-Graduação em QuímicaNesta dissertação, são descritas a síntese e as propriedades térmicas de duas séries de compostos com estrutura ...
Frizon, Tiago Elias Allievi
core