Results 71 to 80 of about 1,413 (178)

Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6. [PDF]

J Med Chem, 2023
König B, Watson PR, Reßing N, Cragin AD, Schäker-Hübner L, Christianson DW, Hansen FK.   +6 more
europepmc   +1 more source

Rapid Assembly of Pyrrole-Ligated 1,3,4-Oxadiazoles and Excellent Antibacterial Activity of Iodophenol Substituents. [PDF]

Molecules, 2023
Kim H, Gu L, Yeo H, Choi U, Lee CR, Yu H, Koo S.   +6 more
europepmc   +1 more source

1,3,4-Oxadiazole as an Anticancer Agent

International Journal For Multidisciplinary Research
The modern era's fastest-growing disease is cancer, it poses a serious threat to people's lives. For the treatment of various cancers, the FDA has approved a number of medications. However, because of the rise in drug toxicity incidents, there is a continual need for the discovery of novel anti-cancer drugs.
Vaishnavi Chopade -, Vinayak Gaware -
openaire   +1 more source

A Graphene Acid - TiO₂ Nanohybrid as Multifunctional Heterogeneous Photocatalyst for the Synthesis of 1,3,4-Oxadiazoles. [PDF]

ACS Appl Mater Interfaces, 2022
Sciarretta M, Barawi M, Navío C, Shea VAPO, Blanco M, Alemán J.   +5 more
europepmc   +1 more source

Novel Macrocyclic 1,3,4-Oxadiazoles as CFTR Modulators for Treating Cystic Fibrosis. [PDF]

ACS Med Chem Lett, 2022
Sabnis RW.
europepmc   +1 more source

Modular and Computational Access to Innocuous Multistep Metal-Free Synthesis of 1,3,4-Oxadiazoles as Enzyme Inhibitors. [PDF]

ACS Omega, 2023
Umair M, Rehman AU, Abbasi MA, Siddiqui SZ, Iqbal J, Khalid H, Rasool S, Khan SU, Zafar F.   +8 more
europepmc   +1 more source

An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches. [PDF]

Biomedicines, 2023
Irfan A, Faisal S, Ahmad S, Saif MJ, Zahoor AF, Khan SG, Javid J, Al-Hussain SA, Muhammed MT, Zaki MEA.   +9 more
europepmc   +1 more source

Design, Synthesis and Bioactivity Evaluation of Novel 2-(pyrazol-4-yl)-1,3,4-oxadiazoles Containing an Imidazole Fragment as Antibacterial Agents. [PDF]

Molecules, 2023
Liu H, Yang S, Li T, Ma S, Wang P, Wang G, Su S, Ding Y, Yang L, Zhou X, Yang S.   +10 more
europepmc   +1 more source

Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity. [PDF]

J Biol Chem, 2023
Cellupica E, Caprini G, Cordella P, Cukier C, Fossati G, Marchini M, Rocchio I, Sandrone G, Vanoni MA, Vergani B, Źrubek K, Stevenazzi A, Steinkühler C.   +12 more
europepmc   +1 more source

A One-Pot Synthesis-Functionalization Strategy for Streamlined Access to 2,5-Disubstituted 1,3,4-Oxadiazoles from Carboxylic Acids. [PDF]

J Org Chem, 2022
Matheau-Raven D, Dixon DJ.
europepmc   +1 more source