Results 171 to 180 of about 12,947 (217)

Novel syntheses of symmetrical 2,5-diaryl-1,3,4-oxadiazoles and 1,4-phenylenebis-1,3,4-oxadiazoles

Russian Chemical Bulletin, 1998
The reactions of trichloromethylarenes with excess hydrazine hydrate in ethanol gives symmetrical 2,5-diaryl-1,3,4-oxadiazoles in 68–96% yields. The reaction of 1,4-bis(trichloromethyl)benzene with acylhydrazines in an ethanol-pyridine mixture gives the corresponding substituted or unsubstituted 1,4-phenylenebis-1,3,4-oxadiazoles in 35–51% yields.
L. I. Belen'kii, S. I. Luiksaar, I. S. Poddubnyi, M. M. Krayushkin   +3 more
openaire   +1 more source

Recent Advancement in Synthesis and Bioactivities of 1,3,4-Oxadiazole

Current Organic Synthesis, 2023
Abstract: Derivatives of 1,3,4-oxadiazole are effective in the treatment and cure of a wide range of diseases in medical chemistry, while industrial development has shown that they can be utilised as corrosion inhibitors and light-emitting diodes.
Tarun, Chaudhary, Prabhat Kumar, Upadhyay   +1 more
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ChemInform Abstract: 1,3,4‐Oxadiazole

ChemInform, 2014
AbstractReview: use of oxadiazole derivatives in in various field like polymer industry and, ost notably, medicinal chemistry; 70 refs.
S. B. Dave, P. Godhani, Y. Ushir
openaire   +1 more source

1,3,4-Oxadiazoles as Anticancer Agents: A Review

Recent Patents on Anti-Cancer Drug Discovery
Abstract: Among the deadliest diseases, cancer is characterized by tumors or an increased number of a specific type of cell because of uncontrolled divisions during mitosis. Researchers in the current era concentrated on the development of highly selective anticancer medications due to the substantial toxicities of conventional cytotoxic drugs ...
Greesh Kumar, Rajnish Kumar, Avijit Mazumder, null Salahuddin, Upendra Kumar   +4 more
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Perfluoro-bis-1,3,4 oxadiazoles

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1965
1. The hydrazides of perfluorodicarboxylic acids of the general formula NH2NHCO(CF2)nCONHNH2 (n= 3,4,8,12) were produced by the action of hydrazine hydrate on the diethyl esters of the perfluorodicarboxylic acids in alcohol solutions. 2.
M. P. Krasuskaya, D. P. Del'tsova, I. L. Knunyants   +2 more
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Aliphatic poly‐1,3,4‐oxadiazoles

Journal of Polymer Science Part A: General Papers, 1965
AbstractThree high molecular weight aliphatic polyoxadiazoles have been prepared by a new route from equimolar amounts of a diphenyl ester of dicarboxylic acid and an anhydrous hydrazine (or a dihydrazide). The resulting polymers have been characterized by microanalysis, intrinsic viscosity, x‐ray diffraction patterns, infrared absorption spectra, and ...
Terunobu Unishi, Masaki Hasegawa
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Anti-inflammatory Activity of Substituted 1,3,4-Oxadiazoles

Journal of Pharmaceutical Sciences, 1994
Various 5-[[(acetamidophen-4-yl)oxy]methyl]-2-(p-substituted phenylamino)-1,3,4-oxadiazoles (4a-4d) were synthesized by cyclization of the corresponding N1-[[(acetamidophen-4-yl)oxy]acetyl]- N4-(p-substituted phenylamino)-3-thiosemicarbazides (3a-3d). All four of the thiosemicarbazides [250 mg/kg, orally (p.o.)] and the corresponding oxadiazoles (250 ...
L V, Nargund, G R, Reddy, V, Hariprasad
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ChemInform Abstract: Synthesis and Antioxidant Activity of Styrylsulfonylmethyl 1,3,4‐Oxadiazoles, Pyrazolyl/Isoxazolyl‐1,3,4‐oxadiazoles.

ChemInform, 2014
AbstractCompound (IIIb) is found to exhibit slightly higher antioxidant activity than the standard ascorbic acid.
Guda Mallikarjuna Reddy, Akkarapalli Muralikrishna, Venkatapuram Padmavathi, Adivireddy Padmaja, Thandaiah Krishna Tilak, Chippada Appa Rao   +5 more
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THE CHEMISTRY OF 1,3,4-OXADIAZOLE DERIVATIVES

Russian Chemical Reviews, 1964
CONTENTS I. Introduction 508 II. Preparation of mono-substituted 1,3,4-oxadiazoles 508 III. Preparation of symmetrical 2,5-substituted 1,3,4-oxadiazoles 508 IV. Preparation of asymmetrical 2,5-substituted 1,3,4-oxadiazoles 509 V. Preparation of poly-1,3,4-oxadiazoles 511 VI.
E P Nesynov, A P Grekov
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Pushing the Limits of Oxygen Balance in 1,3,4-Oxadiazoles

Journal of the American Chemical Society, 2017
Gem-trinitromethyl groups were introduced into a 1,3,4-oxadiazole ring to give the first example of a bifunctionalized single five-membered ring with six nitro groups. 2,5-Bis(trinitromethyl)-1,3,4-oxadiazole (12) has a high calculated crystal density of 2.007 g cm-3 at 150 K (1.941 g cm-3 at 293 K) and a very high positive oxygen balance (39.12 ...
Qiong Yu, Ping Yin, Jiaheng Zhang, Chunlin He, Gregory H. Imler, Damon A. Parrish, Jean’ne M. Shreeve   +6 more
openaire   +2 more sources