Results 71 to 80 of about 8,042 (202)

Synthesis and Study of Some 4-Chlorophenoxy Methyl Substituted amido1,3,4-Oxadiazoles, 1,3,4-Thiadiazoles and 1,2,4-Triazoles from 4-Chloro phenoxy acetic acid [PDF]

مجلة التربية والعلم, 2013
: In this paper the synthesis of some substituted 1,3,4-oxadiazole, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. 4-Chlorophenol was treated with chloroacetic acid to give 4-chlorophenoxy acetic acid (C1) which was reacted with thionyl chloride ...
Mudhar A. Othman, Khalid M. Daoud
doaj   +1 more source

Перспективи застосування гетероциклічних сполук для лікування хворих на туберкульоз легень [PDF]

, 2014
Основна причина погіршення епідемічної ситуації з туберкульозу (ТБ) полягає в зміні біологічних властивостей мікобактерій (МБТ) під впливом антимікобактеріальних препаратів (АМБП) із розвитком полі- та мультирезистентних штамів М ...
Єременчук, Інга Василівна
core  

Recent developments in the chemistry and enzyme inhibitory activity of fused thiazoles and thiadiazoles

Vietnam Journal of Chemistry, Volume 63, Issue 6, Page 872-882, December 2025.
Abstract The combination of cyclization reactions of thiadiazoles and benzothiazoles with Pd‐catalyzed cross‐coupling reactions provided a convenient synthesis of annulated, fluorinated and non‐fluorinated heterocycles, such as 1,3,4‐thiadiazolo[3,2‐a]pyrimidin‐5‐ones, benzothiazolo[3,2‐a]pyridimidin‐4‐ones, benzothiazolo[2,3‐b]quinazolin‐12‐ones and ...
Peter Langer
wiley   +1 more source

Biological activity of heterocyclic systems based on functionally substituted 1,3,4-thia(oxa)diazoles (a review)

Фармацевтичний журнал, 2019
1,3,4-Thiadiazole and oxadiazole hetetocycles are well-known pharmacophore scaffolds, which possess wide possibility for chemical modification and identified diverse pharmacological potential.
M. I. Lelyukh
doaj   +1 more source

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

ChemistryOpen, Volume 14, Issue 11, November 2025.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel, Amr S. Abouzied, Magdi E. A. Zaki, Abdulwahab Alamri, Basant Farag, Saad Alqarni, Sobhi M. Gomha   +6 more
wiley   +1 more source

Room Temperature Synthesis and Antibacterial Activity of New Sulfonamides Containing N,N -Diethyl-Substituted AmidoMoieties [PDF]

, 2012
Sulfonamide drugs which have brought about an antibiotic revolution in medicine are associated with a wide range of biological activities.
Ajani, Olayinka O., Echeme, Johnbull O, Familoni, Oluwole B, Sujiang, Zheng, Wu, Feipeng   +4 more
core   +5 more sources

Interfering Transposable Elements: ISXoo15 Transposase as a First‐in‐Class Antibacterial Target Against Xanthomonas oryzae pv. oryzae

Molecular Plant Pathology, Volume 26, Issue 11, November 2025.
The study identifies the previously unknown transposase ISXoo15 as an antiphytobacterial target. By constructing mutant strains, this enzyme's essential role in regulating bacterial pathogenicity and virulence is revealed. ABSTRACT Current challenges in controlling phytopathogenic bacteria lie in widespread chemical resistance, biosafety concerns, and ...
Funeng Lu, Ting Liu, Tangbing Yang, Ziming Wang, Jianzhuan Li, Chunni Zhao, Huan Wu, Deyu Hu, Baoan Song   +8 more
wiley   +1 more source

Pitting Corrosion Inhibition of Type 304 Austenitic Stainless steel by 2�Amino�5�ethyl�1,3,4�thiadiazole in Dilute Sulphuric Acid [PDF]

, 2015
The electrochemical behaviour and inhibitor protection of 2 amino 5 ethyl 1,3,4 thiadiazole (TTD) on the pitting corrosion of austenitic stainless steel (type 304) in dilute sulphuric acid solution con taminated with recrystallised sodium chloride was
Loto, C. A., Loto, R. T.
core   +1 more source

Ultrasound assisted synthesis of some new 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) derivatives incorporating pyrazolone moiety

Ultrasonics Sonochemistry, 2009
Novel substituted 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) were synthesized from reaction of 1-methyl-5-oxo-3-phenyl-2-pyrazolin-4-thiocarbox-anilide with a series of different hydrazonyl halides or N,N'-diphenyl-oxalodihydrazonoyl dichloride. The reactions were carried out under both conventional and ultrasonic irradiation conditions.
Naglaa M, Abd El-Rahman, Tamer S, Saleh, Mohamed F, Mady   +2 more
openaire   +2 more sources

Anti‐Corrosive Covalent Iodo‐Thiadiazole Catalyst Enables Aqueous Zn─S Batteries with High Coulombic Efficiency

Advanced Materials, Volume 37, Issue 43, October 29, 2025.
In aqueous Zn–S batteries, a covalently bonded iodo–thiadiazole redox mediator suppresses parasitic I3−‐mediated Zn corrosion and enhances Zn–S redox kinetics, enabling pouch cell with a high capacity of 1398 mAh g−1 after 120 cycles. This innovative catalyst design is a leap toward practical and grid‐scale aqueous Zn–S batteries. Abstract Aqueous zinc‐
Jiahao Liu, Yujie Chen, Han Wu, Chao Ye, Shi‐Zhang Qiao   +4 more
wiley   +1 more source