Results 91 to 100 of about 24,842 (217)

Reaction of Nitrones with Phosphinylallenes: DFT Mechanistic Investigations

open access: yesEuropean Journal of Organic Chemistry, Accepted Article.
The reaction between phosphinylallenes and nitrones efficiently leads to 4‐phosphinylpyrrolidin‐3‐ones. The mechanism involved in this reaction was theoretically studied to understand the overall pathway and the stereochemical outcome of the transformation.
Rayhane Hammami   +5 more
wiley   +1 more source

Catalytic Asymmetric Inverse-Electron-Demand 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines with Azlactones: Access to Chiral Tricyclic Tetrahydroisoquinolines.

open access: yesAngewandte Chemie, 2016
Reported herein is a bifunctional-organocatalyst-mediated enantioselective inverse-electron-demand 1,3-dipolar cycloaddition of C,N-cyclic azomethine imines with azlactones.
Xihong Liu   +5 more
semanticscholar   +1 more source

Alkylation and 1,3-Dipolar Cycloaddition of 6-Styryl-4,5-dihydro-2H-pyridazin-3-one: Synthesis of Novel N-Substituted Pyridazinones and Triazolo[4,3-b]pyridazinones

open access: yesJournal of Chemistry, 2013
Some new N-substituted pyridazinones and triazolo[4,3-b]pyridazinones were synthesized, respectively, by simple alkylation and 1,3-dipolar cycloaddition of pyridazin-3-one with nitrile imines.
Souad Mojahidi   +6 more
doaj   +1 more source

Synthesis of Pyrrolidin‐3‐Ones and Spiropyrrolidinones by 1,3‐Dipolar Cycloadditions of Nitrones with Allenylphosphonates

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This work introduces an efficient and gram‐scale microwave‐assisted (3+2) cycloaddition of nitrones with fluorinated allenylphosphonates, yielding diverse 4‐phosphinyl‐pyrrolidin‐3‐ones with exclusive 4,5‐trans diastereoselectivity in moderate to good yields.
Rayhane Hammami   +6 more
wiley   +1 more source

New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition

open access: yesNature, 2015
The bacterial ubiD and ubiX or the homologous fungal fdc1 and pad1 genes have been implicated in the non-oxidative reversible decarboxylation of aromatic substrates, and play a pivotal role in bacterial ubiquinone (also known as coenzyme Q) biosynthesis ...
K. Payne   +14 more
semanticscholar   +1 more source

Decarboxylative 1,3-dipolar cycloadditions of l-proline

open access: yesRSC Advances
l-Proline is widely used in 1,3-dipolar cycloaddition reactions. Azomethine ylide derived from decarboxylative condensation of l-proline and 1,2-dicarbonyl compounds can directly react with various dipolarophiles through 1,3-dipolar cycloaddition.
Fatemeh Doraghi   +6 more
openaire   +2 more sources

Efficient synthesis of 1,3-diaryl-4-halo-1H-pyrazoles from 3-arylsydnones and 2-aryl-1,1-dihalo-1-alkenes

open access: yesBeilstein Journal of Organic Chemistry, 2011
An efficient synthesis of 1,3-diaryl-4-halo-1H-pyrazoles was achieved. The synthesis involves the [3 + 2] dipolar cycloaddition of 3-arylsydnones and 2-aryl-1,1-dihalo-1-alkenes. The process proceeds smoothly in moderate to excellent yields. 1,3-Diaryl-4-
Yiwen Yang   +4 more
doaj   +1 more source

Crystal structure of (2R*,3aR*)-2-phenylsulfonyl-2,3,3a,4,5,6-hexahydropyrrolo[1,2-b]isoxazole

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
The title compound, C12H15NO3S, was prepared by 1,3-dipolar cycloaddition of 3,4-dihydro-2H-pyrrole 1-oxide and phenyl vinyl sulfone. In the molecule, both fused five-membered rings display a twisted conformation.
Yaiza Hernández   +4 more
doaj   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra   +3 more
wiley   +1 more source

Synthesis of Chiral Pyrazoles: A 1,3-Dipolar Cycloaddition/[1,5] Sigmatropic Rearrangement with Stereoretentive Migration of a Stereogenic Group.

open access: yesAngewandte Chemie, 2015
The reactions between terminal alkynes and α-chiral tosylhydrazones lead to the obtention of chiral pyrazoles with a stereogenic group directly attached at a nitrogen atom. The cascade reaction includes decomposition of the hydrazone into a diazocompound,
M. C. Pérez-Aguilar, C. Valdés
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy