Results 101 to 110 of about 24,842 (217)
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas+4 more
wiley +1 more source
A silver-catalyzed 1,3-dipolar cycloaddition of fluorinated azomethine ylides and activated olefins is reported. The reaction offers a straightforward and atom-economical procedure for the preparation of fluorinated pyrrolidines.
Alberto Ponce+3 more
semanticscholar +1 more source
In this paper, we report a highly regioselective 1,3-dipolar cycloaddition (1,3-DC) reaction of nitrilimines with thioaurone derivatives that afforded the hitherto unreported spiropyrazolines. Spectroscopic and spectrometric data were utilized to confirm
Mohamed Bakhouch+10 more
doaj +1 more source
The title compounds were synthesized from C-aryl-N-methylglycines by Naroylation followed by a cyclodehydration to form the corresponding 1,3-oxazolium-5-olates.
Maria Joaquina Vieira+5 more
doaj +1 more source
Controlling Drug Release From Supramolecular Polymer Surfaces by a Click‐To‐Release Reaction
We present a strategy combining reactive supramolecular additives with a covalent click‐to‐release reaction for localized drug delivery. A trans‐cyclooctene additive releases a cytotoxic drug upon tetrazine administration. Fluorescent monitoring confirms release, and cytotoxic tests show effective cancer cell death.
Maritza M. Rovers+6 more
wiley +1 more source
Diethyl 4-acetyl-5-(2-nitrophenyl)pyrrolidine-2,2-dicarboxylate
The title compound, C18H22N2O7, was synthesized by the 1,3-dipolar cycloaddition reaction of but-3-en-2-one, diethyl 2-aminomalonate and 2-nitrobenzaldehyde. In the molecule, the pyrrolidine ring possesses an envelope conformation.
Long He
doaj +1 more source
Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton+3 more
wiley +1 more source
The development of photoredox reactions of 1,3-dipolar cycloaddition of nitrones with alkenes is reported. It offers an efficient synthetic method to obtain isoxazolidine derivatives under mild conditions in synthetically useful yields.
Lewei Zheng+6 more
semanticscholar +1 more source
A rapid and simple procedure was devised for the synthesis of multifunctionalized cyclic β-amino esters and γ-amino alcohols via the 1,3-dipolar cycloaddition of nitrile oxides to β-aminocyclopentenecarboxylates.
Melinda Nonn+3 more
doaj +1 more source
Abstract Objective This study aimed to provide proof‐of‐concept that multi‐receptor antagonist peptides can be generated by covalently linking independent antagonist peptides that block calcitonin gene‐related peptide (CGRP8‐37) or pituitary adenylate cyclase‐activating peptide (PACAP)/vasoactive intestinal peptide (VIP) (PACAP6‐38) activity ...
Zoe Tasma+5 more
wiley +1 more source