Results 31 to 40 of about 1,389 (161)

Enantioselective Cycloaddition Reactions Catalyzed by BINOL-Derived Phosphoric Acids and N-Triflyl Phosphoramides: Recent Advances

Molecules, 2015
Over the last several years there has been a huge increase in the development and applications of new efficient organocatalysts for enantioselective pericyclic reactions, which represent one of the most powerful types of organic transformations.
Felix E. Held, Dominik Grau, Svetlana B. Tsogoeva   +2 more
doaj   +1 more source

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

Synthesis of α‐Pentafluorosulfanylated‐β2,3‐Amino Esters

ChemistryEurope, EarlyView.
De novo α‐SF5‐β2,3‐amino esters are now accessible through a straightforward aza‐Michael reaction using a series of newly developed (E)‐α‐SF5‐α,β‐unsaturated esters. Two new, highly functionalized, contiguous tertiary stereocenters are formed with diastereodivergence governed by the choice of solvent and/or base.
Thi Mo Nguyen, Guilhem Colomer, Oscar Maugue‐Sauze, Nicolas Blanchard, Vincent Bizet, Dominique Cahard   +5 more
wiley   +1 more source

A sequential multistep process for the fully mechanochemical, one-pot synthesis of the antiepileptic drug rufinamide

Green Chemistry Letters and Reviews, 2022
Mechanochemistry is a powerful tool to develop environmentally benign syntheses of active pharmaceutical ingredients. In this context, we report here the synthesis of the anti-epileptic agent rufinamide through a one-pot sequential multi-component ...
Jorge Gómez-Carpintero, Clara Cabrero, Juan Domingo Sánchez, Juan Francisco González, José Carlos Menéndez   +4 more
doaj   +1 more source

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

ChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn, Giulia Castello, Nico J. Meeuwenoord, Martijn Verdoes, Jeroen D. C. Codée, Ferry Ossendorp, Dmitri V. Filippov   +6 more
wiley   +1 more source

(SP,SP)-(–)-(E)-1,2-Bis(methylphenylphosphinoyl)ethene

Acta Crystallographica Section E, 2009
The title compound, C16H18O2P2, possesses two stereogenic P atoms and shows a distorted s–cis conformation of each O=P—C=C moiety. This has been suggested on the basis of the stereochemical result of 1,3-dipolar cycloadditions with ...
doaj   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Dual‐Mode Thio‐MacMillan Organocatalysts: Stereoselective Diels–Alder Reactions or Sacrificial Self‐Cyclization to N‐Bridged Bicyclic Lactams

Chemistry – A European Journal, EarlyView.
The study of the Diels–Alder reaction of cinnamaldehyde and cyclopentadiene, catalyzed by chiral imidazolidine‐4‐thiones, led to the discovery of a highly regio‐ and stereoselective Michael‐addition and consecutive ring closure. Here, the imidazolidine‐4‐thione not only catalytically activates cinnamaldehyde but also participates as the nucleophile to ...
Marian S. R. Ebeling, Luca V. Parziale, Marc Sachsenhauser, Christoph J. B. Seifert, Nathalie J. Kurrle, Oliver Trapp   +5 more
wiley   +1 more source

Switchable Reactivities of Metalated Phosphasilenes Regulated by Reversible 1,2‐Metal Migration

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
We develop novel strategies for the facile synthesis of anionic phosphasilenes in the forms of both P‐metalation and Si‐metalation. The P‐metalated phosphasilene displays a pronounced π‐bond‐driven reactivity toward robust inert molecules, whereas the Si‐metalated analogue behaves as a silylene equivalent via a retro‐1,2‐silver migration.
Huaiyuan Zhu, Shicheng Dong, Xufang Liu, Xiyuan Li, Tobias Weng, Jun Zhu, Shigeyoshi Inoue   +6 more
wiley   +2 more sources

Coumarin–Tetrapyrrolic Macrocycle Conjugates: Synthesis and Applications

Molecules, 2017
This review covers the synthesis of coumarin–porphyrin, coumarin–phthalocyanine and coumarin–corrole conjugates and their potential applications. While coumarin–phthalocyanine conjugates were obtained almost exclusively by tetramerization of coumarin ...
Ana F. R. Cerqueira, Vítor A. S. Almodôvar, Maria G. P. M. S. Neves, Augusto C. Tomé   +3 more
doaj   +1 more source