Results 1 to 10 of about 235,743 (243)

First Organocatalytic Asymmetric Synthesis of 1-Benzamido-1,4-Dihydropyridine Derivatives. [PDF]

open access: yesMolecules, 2018
Preliminary results concerning the first asymmetric synthesis of highly functionalized 1-benzamido-1,4-dihydropyridine derivatives via the reaction of hydrazones with alkylidenemalononitriles in the presence of β-isocupreidine catalyst are reported.
Auria-Luna F   +2 more
europepmc   +3 more sources

1,4-Dihydropyridine: synthetic advances, medicinal and insecticidal properties. [PDF]

open access: yesRSC Adv, 2022
1,4-Dihydropyridine (1,4-DHP) is one of the foremost notable organic scaffolds with diverse pharmaceutical applications. This study will highlight recent accomplishments in the construction of 1,4-DHP with structural and functional modifications using ...
A P, Makam P.
europepmc   +2 more sources

Calcined Layered Double Hydroxides: Catalysts for Xanthene, 1,4-Dihydropyridine, and Polyhydroquinoline Derivative Synthesis. [PDF]

open access: yesACS Omega, 2020
This work is generally focused on the synthesis of NiFeTi-layered double hydroxides (LDHs) using a hydrothermal route, which were calcined at various temperatures (varying from 200 to 600 °C).
Rathee G   +4 more
europepmc   +2 more sources

An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates. [PDF]

open access: yesBeilstein J Org Chem, 2022
A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO)6-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates ...
Zanakhov TO   +3 more
europepmc   +2 more sources

Comparison between 1,2-Dihydropyridine and 1,4-Dihydropyridine on Hydride-Donating Ability and Activity. [PDF]

open access: yesMolecules, 2022
In this paper, detailed comparisons of the driving force in thermodynamics and intrinsic force in the kinetics of 1,2-dihydropyridine and 1,4-dihydropyridine isomers of PNAH, HEH, and PYH in hydride transfer reactions are made. For 1,2-PNAH and 1,4-PNAH,
Zhang JY, Zhu XQ.
europepmc   +2 more sources

1,4-Dihydropyridine Antihypertensive Drugs: Recent Advances in Photostabilization Strategies. [PDF]

open access: yesPharmaceutics, 2019
The 1,4-dihydropyridine (DHP) drugs are nowadays the most used drugs in the treatment of hypertension. However, all the structures in this series present a significant sensitivity to light, leading to the complete loss of pharmacological activity.
De Luca M, Ioele G, Ragno G.
europepmc   +2 more sources

Green synthesis, molecular docking and anticancer activity of novel 1,4-dihydropyridine-3,5-Dicarbohydrazones under grind-stone chemistry

open access: yesGreen Chemistry Letters and Reviews, 2020
The reaction of 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarbohydrazide with variety of carbonyl compounds such as substituted benzaldehydes, cycloalkanones and hetero-cyclic ketones under grinding method under catalyst- and solvent-free ...
Sobhi M. Gomha   +4 more
doaj   +2 more sources

Antimicrobial, anticoagulant, and cytotoxic evaluation of multidrug resistance of new 1,4-dihydropyridine derivatives. [PDF]

open access: yesSaudi J Biol Sci, 2018
A new series of 1,4-dihydropyridine derivatives (2a–h, 3a–e, and 4a–e) were systematically designed and synthesized via ultrasound irradiation methods with easy work-up and good yields. Compounds structures were confirmed by IR, 1H NMR, 13C NMR, and mass
Ahamed A   +4 more
europepmc   +2 more sources

Synthesis of efficient cobalt-metal organic framework as reusable nanocatalyst in the synthesis of new 1,4-dihydropyridine derivatives with antioxidant activity.

open access: yesFront Chem, 2022
Efficient cobalt–metal organic framework (Co-MOF) was prepared via a controllable microwave-assisted reverse micelle synthesis route. The products were characterized by SEM image, N2 adsorption/desorption isotherm, FTIR spectrum, and TG analysis. Results
Salahdin OD   +9 more
europepmc   +2 more sources

1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress. [PDF]

open access: yesOxid Med Cell Longev, 2016
Many 1,4-dihydropyridines (DHPs) possess redox properties. In this review DHPs are surveyed as protectors against oxidative stress (OS) and related disorders, considering the DHPs as specific group of potential antioxidants with bioprotective capacities.
Velena A   +6 more
europepmc   +2 more sources

Home - About - Disclaimer - Privacy