Results 111 to 120 of about 235,743 (243)
Transfer hydrosilylation [PDF]
, 2016 Transfer hydrogenation is without question a common technology in industry and academia. Unlike its countless varieties, conceptually related transfer hydrosilylations had essentially been unreported until the recent development of a radical and an ionic
Oestreich, Martin
core +1 more source
MoleculesDipines are a type of important antihypertensive drug as L-calcium channel blockers, whose core skeleton is the 1,4-dihydropyridine structure. Since the dihydropyridine ring is a key structural factor for biological activity, the thermodynamics of the ...
Guang-Bin Shen +4 more
doaj +1 more source
Molecules, 2003 Domestic microwave ovens as well as laboratory reactors have been successfully employed to prepare dialkyl 1,4-dihydropyridine-3,5-dicarboxylates and to induce the synthesis of the corresponding aromatic derivatives.
Annie Mayence, Jean Jacques Vanden Eynde
doaj +1 more source
CXCL12-induced neurotoxicity critically depends on NMDA receptor-gated and L-type Ca2+ channels upstream of p38 MAPK. [PDF]
, 2016 BackgroundThe chemokine receptor CXCR4 (CD184) and its natural ligand CXCL12 contribute to many physiological processes, including decisions about cell death and survival in the central nervous system.
Kaul, Marcus +5 more
core +1 more source
One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor [PDF]
, 2013 The Bohlmann–Rahtz pyridine synthesis and the Hantzsch dihydropyridine synthesis can be carried out in a microwave flow reactor or using a conductive heating flow platform for the continuous processing of material. In the Bohlmann–Rahtz reaction, the use
Bagley, Mark C +4 more
core +2 more sources
Antileishmanial and Antitoxoplasmal Activities of 1,4-dihydropyridines
ACS OmegaAbstract: We have synthesized 24 1,4-dihydropyridine compounds (1,4-DHPs) with different substituents at the aromatic ring by microwave-assisted one-pot Hantzsch multicomponent reac-tion and evaluated their in vitro activities against Toxoplasma gondii and Leishmania major.
Thaís Oliveira +9 more
openaire +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2018 In the title racemic compound, ethyl 4-(4-dimethylaminophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, the common structural features in this type of compound, such as the flat-boat conformation of the 1,4-dihydropyridine (1,4-
Scott A. Steiger +2 more
doaj +1 more source
Preparation of indole alkaloids via 1,4-dihydropyridine stage or cyano-masked iminium intermediates [PDF]
, 2004 Methods to synthesise substituted pyridine derivatives utilising 1,4-dihydropyridines were studied. Addition of nucleophiles to N-alkyl pyridinium salts and application of the products to alkaloid synthesis were investigated.
Putkonen, Tiina
core
Chemical and pharmaceutical bulletin, 2015 The multi-component reaction of either acetoacetanilide derivative 1a or b with any of the aldehyde derivatives 2a-d and malononitrile 3 in the presence of triethylamine as a catalyst gave the 4H-pyran derivatives 4a-g, respectively.
Rasha A. Azzam, R. Mohareb
semanticscholar +1 more source
Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
Acta Crystallographica Section E, 2011 The title compound, C17H16N2O6, is a decomposition product of the hypertension drug nifedipine [systematic name: dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate].
Juanjuan Zheng +4 more
doaj +1 more source