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1,4-Dihydropyridines bearing a pharmacophoric fragment of lidoflazine
Bioorganic & Medicinal Chemistry, 1996A series of 1,4-dihydropyridines bearing a pharmacophoric fragment of lidoflazine was synthesized. The compounds were evaluated for inotropic, chronotropic, and calcium antagonist activities. All compounds behave as inotropic and chronotropic agents, except for compounds 4b, 5a, and 5b, which exhibit a rather weak calcium antagonism in vascular smooth ...
Chiarini A. +5 more
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Reactions of 1,4-dihydropyridines (review)
Chemistry of Heterocyclic Compounds, 1993The literature published over the period 1986–1990 on the chemical properties (oxidation, addition, substitution, reactions of the functional groups, etc.) of 1,4-dihydropyridines is correlated.
A. Sausin'sh, G. Dubur
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Vicinal diamination of 1,4-dihydropyridines
Chemical Communications, 1998Electrophilic interaction of iodine with N-alkyl-1,4-dihydropyridines 1 in the presence of secondary amines stereoselectively leads to the corresponding trans-2,3-diamino-1,2,3,4-tetrahydropyridines 2 in satisfactory yields (79–94%); the method allows the synthesis of piperidine, pyrrolidine, morpholine and piperazine derivatives.
Rodolfo Lavilla +4 more
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The alkylation of hantzsch 1,4‐dihydropyridines
Journal of Heterocyclic Chemistry, 1986AbstractThe reaction of carbanions derived from Hantzsch 1,4‐dihydropyridines with alkyl halides was studied and methods for mono‐ and di‐alkylation were devised.
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Journal of the American Chemical Society, 1965
Newell C. Cook, James E. Lyons
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Newell C. Cook, James E. Lyons
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Photoelectron spectra of 1,4-dihydropyridine and N-methyl-1,4-dihydropyridine
The Journal of Organic Chemistry, 1974T. Koenig, H. Longmaid
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1,4-Dihydropyridine Derivatives: An Overview of Synthesis Conditions and Biological Tests
Current Organic Chemistry, 2023Sérgio Thomasi, Larissa da Silva
exaly
Oxidation of 1,4-dihydropyridines
Chemistry of Heterocyclic Compounds, 1973Ya. R. Uldrikis +2 more
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Reactions of 1,4-Dihydropyridines
HETEROCYCLES, 1988Gunãrs Duburs, Alvils Sausins
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ChemInform Abstract: PHOTOELECTRON SPECTRA OF 1,4‐DIHYDROPYRIDINE AND N‐METHYL‐1,4‐DIHYDROPYRIDINE
Chemischer Informationsdienst, 1974T. KOENIG, H. LONGMAID
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