Results 151 to 160 of about 370,384 (214)

1,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress. [PDF]

Oxid Med Cell Longev, 2016
Velena A, Zarkovic N, Gall Troselj K, Bisenieks E, Krauze A, Poikans J, Duburs G.   +6 more
europepmc   +1 more source

Breaking the Aromaticity Trap: <i>N</i>-Silylation-Induced Formation of Stable 2,3-Dihydro-4-dialkylaminopyridin-1-iums. [PDF]

J Org Chem
Verkhov VA, Yakubenko AA, Begović B, Tupikina EY, Antonov AS.   +4 more
europepmc   +1 more source

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Coumarin 1,4-Dihydropyridine Derivatives

Bioorganic & Medicinal Chemistry, 1998
A series of 1,4-dihydropyridines bearing a coumarin moiety in 4-position was synthesized. The compounds were evaluated for inotropic, chronotropic and calcium antagonist activities. The replacement of the o-nitrophenyl moiety of nifedipine with a coumarin or phenylcoumarin system is accompanied by a decrease of the activity on myocardial and vascular ...
Valenti P., Rampa A., Budriesi R., Bisi A., Chiarini A.   +4 more
openaire   +2 more sources

Solid state photochemistry of 1,4-dihydropyridines

Bioorganic & Medicinal Chemistry Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Hamid R, Memarian, Arsalan, Mirjafari
openaire   +2 more sources

Iodocyclization of 1,4-dihydropyridines

Tetrahedron Letters, 1998
Abstract Iodine (or related species) addition to 1,4-dihydropyridines, with properly attached substituents at the nitrogen atom, leads to the corresponding 3-iodotetrahydropyridinium ions, which undergo an internal nucleophilic attack to furnish regio- and stereoselectively iodobi(poly)lteterocyclic ring systems in good yields.
Rodolfo Lavilla, Oscar Coll, Marta Nicolàs, Joan Bosch   +3 more
openaire   +1 more source

The oxidation of 1,4-dihydropyridines

Chemistry of Heterocyclic Compounds, 1970
The olefinic bond of methenylbisindan-1,3-dione, 2-benzylideneindan-1, 3-dione, and its derivatives is easily reduced by many 1, 4-dihydropyridines. Under the conditions described, other functional groups are untouched. These Β-dicarbonyl compounds are utilized to compare the effects of substituents in 1,4-dihydropyridines on their reactivity in the ...
G. Ya. Dubur, Ya. R. Uldrikis
openaire   +1 more source

1,4-Dihydropyridines and the 1,4-Dihydropyridine Receptor

1993
The 1,4-dihydropyridine nifedipine is a first-generation drug of major significance in the treatment of cardiovascular disorders including hypertension, peripheral vascular disorders and angina in its several forms. Nifedipine is one of a chemically and pharmacologically heterogeneous group of drugs that includes also verapamil and diltiazem and which ...
openaire   +1 more source

Aromatization of 1,4‐Dihydropyridines with Selenium Dioxide.

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Xiao-hua Cai, Hai-jun Yang, Guo-lin Zhang   +2 more
openaire   +1 more source