Results 51 to 60 of about 235,743 (243)
TRPA1 channels: Novel targets of 1,4-dihydropyridines [PDF]
Transient receptor potential type A1 (TRPA1) channels are cation permeable channels activated by irritant chemicals and pungent natural compounds. Their location in peptidergic sensory terminals innervating the skin and blood vessels makes them important effectors of vasodilator responses of neural origin.
Fajardo, Otto +3 more
openaire +3 more sources
Reactions of biologically inspired hydride sources with B(C6F5)3 [PDF]
The combination of 1-benzyl-1,4-dihydropyridines with the strong Lewis acid, B(C6F5)3, generates a stable pyridinium borohydride species in high yields (94%) in as little as 10 min.
Luk, Louis Y. P. +3 more
core +1 more source
Sodium N-(3,5-Bis(ethoxycarbonyl)-2,6-dimethyl-1,4-dihydropyridine-4-carbonyl)-l-methioninate
The development of the methods for amide bond formation is important for various uses in the laboratory and industrial applications. The compounds combined in their structures 1,4-dihydroisonicotinic acids and amino acids linked with an amide bond can be
Egils Bisenieks +5 more
doaj +1 more source
7-(3-Nitrophenyl)-9,10-dihydro-7H-benzo[h]cyclopenta[b]quinolin-8(11H)-one
In the title compound, C22H16N2O3, the naphthalene ring, the 1,4-dihydropyridine ring and the cyclopent-2-enone ring are nearly coplanar, with the dihedral angles between the neighbouring rings being 1.93 (11) and 2.30 (9)° ...
Tuanjie Li, Honghong Zhang
doaj +1 more source
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang +6 more
wiley +1 more source
Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates. [PDF]
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions. The use of TBD is crucial for the successful aminolysis of ethoxycarbonylmethyl ester of 1,4-dihydropyridines with secondary amines as
Vigante B +9 more
europepmc +5 more sources
The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis
Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio +2 more
wiley +1 more source
Rearrangement of o-Nitrobenzaldehyde in the Hantzsch Reaction
The reaction of 5-hydroxy-2-nitrobenzaldehyde with ethyl acetoacetate in ammonia gave the two expected isomeric 1,4- and 1,2-dihydropyridines resulting from the normal Hantzsch reaction.
R. MartÃÂnez +7 more
doaj +1 more source
1,4-Dihydropyridine and polyhydroquinoline derivatives have been prepared efficiently in a one-pot synthesis via Hantzsch condensation using nanosized titanium dioxide as a heterogeneous catalyst. The present methodology offers several advantages such as
Alaee, E. +7 more
core +1 more source
Organophotoredox/Cobalt‐Catalyzed Retro‐Hydroformylation of Aldehydes
A new photoredox/cobalt retro‐hydroformylation is developed. This one‐pot two‐step process involves the in situ formation of the corresponding 1,4‐dihydropyridine as key intermediate. Under mild reaction conditions, alkenes are efficiently produced from a wide range of aliphatic α‐monosubstituted aldehydes, with high functional‐group tolerance.
Augustin Nouaille +3 more
wiley +1 more source

