Results 81 to 90 of about 235,743 (243)

Transfer Hydrogenation: Advances in Manganese and Nickel Metal Catalysis

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Transfer hydrogenation (TH) of ketones, catalyzed by transition–metal complexes, produces alcohols, which are important building blocks in the pharmaceutical and fine chemical industries. For a long time, catalysts based on noble metals such as ruthenium, rhodium, and iridium have dominated the TH of ketones.
James Kamau, George S. Nyamato, Joanne Ogunah, Munmun Bardhan   +3 more
wiley   +1 more source

Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame. [PDF]

, 2016
The endoplasmic reticulum (ER)-anchored hepatic cytochromes P450 (P450s) are enzymes that metabolize endo- and xenobiotics i.e. drugs, carcinogens, toxins, natural and chemical products.
Correia, Maria Almira, Kim, Sung-Mi, Liu, Yi, Nabavi, Noushin, Wang, YongQiang   +4 more
core   +1 more source

Recent Synthetic Advances in C–H/N–H Functionalization of 1H‐Pyrazoles: Diverse Strategies Across Variously Substituted Scaffolds

The Chemical Record, Volume 25, Issue 12, December 2025.
Systematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Karolina Dzedulionytė Müldür, Asta Žukauskaitė, Algirdas Šačkus, Eglė Arbačiauskienė   +3 more
wiley   +1 more source

1,1′-[4-(2,4-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]diethanone

Acta Crystallographica Section E, 2011
In the title compound, C17H17Cl2NO2, the central 1,4-dihydropyridine ring adopts a flattened-boat conformation. The ethanone substituents of the dihydropyridine ring at positions 3 and 5 have synperiplanar (cis) or antiperiplanar (trans) conformations ...
J. Kalyana Sundar, B. Palakshi Reddy, V. Vijayakumar, S. Natarajan, J. Suresh, P. L. Nilantha Lakshman   +5 more
doaj   +1 more source

biobibliogrāfija II [PDF]

, 2015
Latvijas Zinātņu akadēmijas akadēmiķe profesore Vija Zaiga Kluša : biobibliogrāfija II / Latvijas Universitātes Akadēmiskā bibliotēka; sast. Dagnija Ivbule; korektore Gita Bērziņa; maketu veidojusi Baiba Lazdiņa.
Ivbule, Dagnija, LU Akadēmiskā bibliotēka   +1 more
core  

Repurposing drugs to fast-track therapeutic agents for the treatment of cryptococcosis [PDF]

, 2018
Many infectious diseases disproportionately affect people in the developing world. Cryptococcal meningitis is one of the most common mycoses in HIV-AIDS patients, with the highest burden of disease in sub-Saharan Africa.
Afeltra, Bicanic, Butts, Byrnes, Catterall, Ceballos, Chatterji, Chong, Chrysant, Clinical and Laboratory Standards Institute (CLSI), Clinical and Laboratory Standards Institute (CLSI), Cruz, Cruz, Cumino, Dehdashti, Del Poeta, Dzoyem, Edlind, Espinel-Ingroff, Feldmeier, Gaggi, Hagen, Hong, Hong, Horton, Jarvis, Joffe, Kneale, Lai, Lassègue, Liu, Liu, Loyse, Meiring, Nixon, Oprea, Park, Peiter, Perfect, Prole, Rabjohns, Rajasingham, Rhein, Samantaray, Smith, Spagnuolo, Spitzer, Teng, Téllez-Girón, Zhai, Zhai   +50 more
core   +3 more sources

Chemistry, Applications, and Synthesis Methods of Indole Derivatives: A Comprehensive Review

The Chemical Record, Volume 25, Issue 12, December 2025.
Indole and its derivatives represent a vital class of heterocycles with broad applications in pharmaceuticals, agrochemicals, and materials science. This review explores their applications, biosynthesis, key derivatives such as tryptophan, and presents an overview of both classical and modern synthetic methodologies, with a focus on sustainable ...
Raphael Silva Moratório de Moraes, Ana Beatriz Mestre Botelho, Gabriel Tavares de Almeida Pinto, Searitha Couto Rodrigues, Maria Tereza Miranda Martins, Deivid Lucas Alves Soares, Camille Cardoso Cruz, Aline de Almeida Pinto, Flaviana Rodrigues Fintelman Dias, Patricia Dias Fernandes, Anna Claudia Cunha   +10 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +86 more
wiley   +1 more source

Diisobutyl 4-(3-ethoxy-4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Acta Crystallographica Section E, 2012
The asymmetric unit of the title compound, C25H35NO6, contains two independent molecules. In each molecule, the 1,4-dihydropyridine ring adopts a flattened boat conformation. The dihedral angles between the 1,4-dihydropyridine and benzene rings are 87.55&
Hoong-Kun Fun, Madhukar Hemamalini, B. Palakshi Reddy, V. Vijayakumar, S. Sarveswari   +4 more
doaj   +1 more source

Diversity of felodipine solvates: Structure and physicochemical properties [PDF]

, 2015
Solvates of the calcium-channel blocking agent felodipine with three structurally related common organic solvents, acetone (ATN), dimethyl sulfoxide (DMSO) and acetophenone (APN), are described.
Bauer-Brandl, A, Bond, AD, Perlovich, GL, Solanko, KA, Surov, AO   +4 more
core   +2 more sources