Activity of the antiarrhythmic drug amiodarone against Leishmania (L.) infantum: an in vitro and in vivo approach [PDF]
Background: Considering the high toxicity and limited therapies available for treating visceral leishmaniasis (VL), the drug repositioning approach represents a faster way to deliver new therapies to the market.
A Cataldi +40 more
core +3 more sources
Dihydropyridine derivatives modulate heat shock responses and have a neuroprotective effect in a transgenic mouse model of Alzheimer’s disease [PDF]
Heat shock proteins (Hsps) have chaperone activity and play a pivotal role in the homeostasis of proteins by preventing misfolding, by clearing aggregated and damaged proteins from cells and by maintaining proteins in an active state. Alzheimer’s disease
Balogh, Gábor +15 more
core +1 more source
AROMATIZATION OF 1,4-DIHYDROPYRIDINES WITH FREE RADICAL REAGENTS [PDF]
Oxidation of different types of 1,4-dihydropyridines with diphenylpicrylhydrazyl (DPP) and benzoyl peroxide (Bz2O2) as free radical oxidizing agents to pyridine derivatives is reported and a mechanism for this oxidation is also proposed.
doaj
Elektroniskā versija nesatur pielikumusMonokatjonu un dikatjonu jonu šķidrumu izmantošana C–C saites veidošanas reakcijās. Priede E., zinātniskais vadītājs Dr. h. ķīm., prof. Zicmanis A.
Priede, Elīna
core +1 more source
Синтез і протимікробна дія нових 4-піразоловмісних 1,4-дигідропіридин-3,5-дикарбоксилатів і 3,4-дигідро-піримідин-5-карбоксилатів [PDF]
Трикомпонентною циклоконденсацією етил 4-формілпіразол-3-карбоксилатів із етилацетоацетатом та амонію ацетатом або сечовиною отримані відповідно 4-[(3-етоксикарбоніл)-4-піразоліл]-1,4-дигідро-3,5-піридиндикарбоксилати і 4-[(3-етоксикарбоніл)-4-піразоліл]-
Барус, М. М. +3 more
core
Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
A good range of 1,4-dihydropyridines bearing a carbamate moiety on the 4-position were synthesized from the primary reaction of different hydroxyaldehydes with phenyl isocyanates and the subsequent reaction of the obtained carbamates with methyl ...
Davood Habibi +2 more
doaj +1 more source
Development of Self-Assembling bis-1,4-Dihydropyridines: Detailed Studies of Bromination of Four Methyl Groups and Bromine Nucleophilic Substitution. [PDF]
Kaukulis M +4 more
europepmc +1 more source
A facile synthesis of N-H-and N-substituted acridine-1,8-diones under sonic condition [PDF]
Synthesis of an assembly of structurally important N-H- and N-substituted acridine-1,8-diones by CAN (ceric ammonium nitrate) catalysed one-pot four-component reaction of electron-deficient and electron-rich aromatic aldehydes and aromatic amines or ...
Pasha, M.A., Sudha, S.
core +3 more sources
Correction: AlCl3@ZnO nanostructured material: an efficient green catalyst for the one-pot solvent-free synthesis of 1,4-dihydropyridines. [PDF]
Shinde ST +7 more
europepmc +1 more source
An efficient method for the synthesis of new heteroaryl substituted dihydropyridine derivatives via a one-pot four-component coupling reaction of heteroaldehyde, 1,3-diketone, ethylacetoacetate, and amonium acetate in the presence of cellulose-sulfuric ...
Manouchehr Mamaghani +3 more
doaj +1 more source

