Results 41 to 50 of about 62,864,054 (165)

Regulation of Calcium Intestinal Absorption in the Camel Calf (Camelus dromedarius)

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2003
Postprandial hypercalcemia and hyperphosphatemia, as well as intestinal calcium (Ca) absorption were measured in 12 newborn camels. They were divided into four groups of three animals. Groups 1 and 2 received an i.v.
M. El Khasmi, F. Riad, A. Safwate, M. Farh, A. Belhouari, K. Hidane, N. El Abbadi, V. Coxam, B. Faye   +8 more
doaj   +1 more source

Dynamics of Kidney Calcium and Phosphorus Mineral Handling in Laying Hens During the Transition to Egg Production

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT The transition from immature pullets to sexually mature female chickens is accompanied by pronounced structural and functional modifications. This is accompanied by coordinated changes in hormonal and metabolic pathways that primarily regulate reproduction, nutrient utilization, and mineral homeostasis to compensate for temporary imbalances ...
Henry Reyer, Michael Oster, Hiba Qasir, Siriluck Ponsuksili, Vera Sommerfeld, Markus Rodehutscord, Klaus Wimmers   +6 more
wiley   +1 more source

1α,25(OH)2D3 Suppresses the Migration of Ovarian Cancer SKOV-3 Cells through the Inhibition of Epithelial–Mesenchymal Transition

, 2016
Ovarian cancer is the most lethal gynecological malignancy due to its high metastatic ability. Epithelial-mesenchymal transition (EMT) is essential during both follicular rupture and epithelium regeneration.
Yong-Feng Hou, Guang-Ming Zhou, Bing-Yan Li, Zeng-Li Zhang, Li-Zhi Liu, He-Mei Zhang, Si-Hai Gao, Ping Wang, Meng-Xuan Ye   +8 more
core   +1 more source

The effects of mitotane and 1α,25-dihydroxyvitamin D3 on Wnt/beta-catenin signaling in human adrenocortical carcinoma cells [PDF]

, 2019
Purpose: Mitotane is the only chemotherapeutic agent available for the treatment of adrenocortical carcinoma (ACC), however, the anti-neoplastic efficacy is limited due to several side-effects in vivo.
Rubin B., Pezzani R., Fallo F., Rebellato A., Pilon C.   +4 more
core   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

Periodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron, Nathan E. Estrin, Ana Paz, Reinhard Gruber, Nima Farshidfar, Yufeng Zhang, Anton Sculean, Thomas G. Wiedemann, Paras Ahmad   +8 more
wiley   +1 more source

The Vitamin D Receptor in Osteoblast-Lineage Cells Is Essential for the Proresorptive Activity of 1α,25(OH)2 D3 In Vivo [PDF]

, 2021
松本歯科大学博士（歯学）2020甲第238号application/pdf要旨我々は以前、活性型ビタミンD3 [1α,25(OH)2D3]製剤であるエルデカルシトールの薬用量の投与は、骨吸収を抑制することで、骨量を増加させることを報告した。この骨吸収抑制効果は、骨芽細胞系列細胞のビタミンD受容体（VDR）を介することを明らかにした。本研究において我々は、骨芽細胞系列細胞特異的VDR欠損（Ob-VDR-cKO）マウスを用いて、1α,25(OH ...
Uehara, Shunsuke, Kato, Shigeaki, Mori, Tomoki, Udagawa, Nobuyuki, Nakamichi, Yuko, Yamamoto, Yoko, Horibe, Kanji, Yasuda, Hisataka, Takahashi, Naoyuki, 森, 智紀, Koide, Masanori   +10 more
core   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Klotho Deficiency Impairs Distal Potassium Homeostasis Through mTORC1‐Dependent Suppression of ROMK

Acta Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT Aim Hyperkalemia is prevalent in the elderly, and underlying molecular mechanisms remain incompletely understood. We hypothesized that Klotho deficiency, a feature of aging, impairs renal potassium homeostasis and contributes to hyperkalemia. Methods Klotho heterozygous knockout (KLhet) mice, characterized by reduced Klotho levels, were used ...
Wakako Kawarazaki, Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Daigoro Hirohama, Kohei Ueda, Takeshi Marumo, Toshiro Fujita   +6 more
wiley   +1 more source

1α,25(OH)2D3 attenuates IL-6 and IL-1β-mediated inflammatory responses in macrophage conditioned medium-stimulated human white preadipocytes by modulating p44/42 MAPK and NF-κB signaling pathways

Diabetology & Metabolic Syndrome, 2019
Background Metabolic syndrome is characterized by macrophage infiltration and inflammatory responses—metaflammation in adipose tissue. IL-6 and IL-1β could mediate the inflammatory responses in macrophage stimulated-preadipocytes by modulating MAPK and ...
Jingjing Zhu, Chen Bing, John P. H. Wilding   +2 more
doaj   +1 more source

Protective effect of 1α,25-dihydroxyvitamin D3 on effector CD4+ T cell induced injury in human renal proximal tubular epithelial cells. [PDF]

PLoS ONE, 2017
The aim of this study was to investigate the protective effect of 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] on effector CD4+ T cells or on inflammatory cytokine-induced injury in human renal proximal tubular epithelial cells (HRPTEpiC).First, we ...
Byung Ha Chung, Bo-Mi Kim, Kyoung Chan Doh, Mi-La Cho, Kyoung Woon Kim, Chul Woo Yang   +5 more
doaj   +1 more source