Results 81 to 90 of about 62,864,054 (165)

Influence of 1α,25-dihydroxyvitamin D3 on Calcium and Phosphorus Secretion of the Mammary Gland in Lactating Camels

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2001
Plasma calcium (Ca) and inorganic phosphorus (Pi) levels, and content of these minerals in milk were measured in six thirdparity she-camels after i.v. administration of 1α,25-dihydroxyvitamin D3 [1α,25-(OH)2D3].
M. El Khasmi   +9 more
doaj   +1 more source

Longitudinal Single‐Cell Transcriptomic Profiling Reveals Dynamic Immune Cell Alterations During Burosumab Therapy in X‐Linked Hypophosphatemia

open access: yesPediatric Discovery, Volume 4, Issue 2, June 2026.
This longitudinal single‐cell study reveals dynamic immune remodeling during burosumab therapy in pediatric X‐linked hypophosphatemia (XLH), highlighting coordinated changes in T cell subtypes (Th2, Th17, and Treg) and natural killer cell subtypes (NK2 and NK3) and immune pathways linked to osteoclast differentiation and treatment response.
Yue Xie   +6 more
wiley   +1 more source

The impact of vitamin D in breast cancer: genomics, pathways, metabolism

open access: yesFrontiers in Physiology, 2014
Nuclear receptors exert profound effects on mammary gland physiology and have complex roles in the etiology of breast cancer. In addition to receptors for classic steroid hormones such as estrogen and progesterone, the nuclear vitamin D receptor (VDR ...
Carmen Judith Narvaez   +9 more
doaj   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

open access: yesCell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang   +10 more
wiley   +1 more source

Vitamin D and the Epithelial to Mesenchymal Transition

open access: yesStem Cells International, 2016
Several studies support reciprocal regulation between the active vitamin D derivative 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the epithelial to mesenchymal transition (EMT).
María Jesús Larriba   +2 more
doaj   +1 more source

Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G.   +5 more
wiley   +1 more source

Hyperosmotic Stimulus Down-regulates 1α, 25-dihydroxyvitamin D₃-induced Osteoclastogenesis by Suppressing the RANKL Expression in a Co-culture System [PDF]

open access: yes, 2005
The hyperosmotic stimulus is regarded as a mechanical factor for bone remodeling. However, whether the hyperosmotic stimulus affects 1α, 25-dihydroxyvitamin D3 (1α,25(OH)2D3)-induced osteoclastogenesis is not clear.
신동민   +6 more
core  

Utilização da vitamina D3 e seus metabólitos na alimentação de frangos de corte sobre parâmetros imunológicos e morfometria intestinal

open access: yesPesquisa Veterinária Brasileira, 2014
Os efeitos da suplementação da vitamina D3 e de seus diferentes metabólitos foram avaliados na resposta imune e na morfometria intestinal de frangos de corte.
Ana Flávia Q. Garcia Guerra   +5 more
doaj   +1 more source

1α,25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells

open access: yes, 2013
1α,25-Dihydroxyvitamin D3 (1α,25(OH) 2D3) has antitumor activity in addition to its classical action on calcium metabolism and bone tissue biology. It is thought to regulate the expression of multiple target genes and thus modulate processes critical for
García, Marta   +6 more
core   +1 more source

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