Results 81 to 90 of about 327,715 (297)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Comparison of P1 and 16S rRNA genes for detection of Mycoplasma pneumoniae by nested PCR in adults in Zhejiang, China

Journal of Infection in Developing Countries, 2015
Introduction: Mycoplasma pneumoniae (M. pneumoniae) is the most common atypical pathogen that causes respiratory infections in humans. Laboratory tests are important in the diagnosis of M. pneumoniae because of the atypical features in clinical signs and
Zibo Zhou, Xiangzhi Li, Xiaojian Chen, Lili Yao, Changwang Pan, Huicong Huang, Fangjun Luo, Xiaoping Zheng, Xiaojing Sun, Feng Tan   +9 more
doaj   +1 more source

Ovine pedomics : the first study of the ovine foot 16S rRNA-based microbiome [PDF]

, 2011
We report the first study of the bacterial microbiome of ovine interdigital skin based on 16S rRNA by pyrosequencing and conventional cloning with Sanger-sequencing.
A Dhawi, AL Cogen, AP Escayg, Atiya Ul-Hassan, BF Langworth, BH Jost, Brian B Oakley, C Lozupone, Claire L Russell, DA Murdoch, DJ Lane, DJ Stewart, DL Emery, DS Roberts, E Pruesse, E Zaura, EA Grice, EA Grice, Elizabeth MH Wellington, G Bennett, G Conrads, G Jones, G Muyzer, G Sayers, GC Baker, GR Carter, Graham F Medley, H Ulbegi-Mohyla, H Zhou, I Demirkan, IH Davies, J Kaler, J Kaler, J Kaler, JA Frank, Jasmeet Kaler, JC Chin, JP Galkiewicz, JR Egerton, K Klitgaard, Laura E Green, LE Green, Leo A Calvo-Bado, LJ Moore, Luci Witcomb, M Chrino-Trejo, MC Liu, Miloslav Kocur, NJ Evans, NJ Evans, PA Lawson, PD Schloss, PD Schloss, RD Naylor, RE Ley, RJ Collighan, Rose Grogono-Thomas, RS Howell-Jones, S La Fontaine, S Lavín, S Piriz Duran, S Tadepalli, Scot E Dowd, SE Dowd, SJ Billington, TG Nagaraja, TM Skerman, TZ DeSantis, TZ DeSantis Jr, Vicky Bateman, W Li, W Ludwing, WE Kloos, WG Weisburg, WIB Beveridge, William Gaze   +75 more
core   +2 more sources

Sequence Diversity of Neisseria meningitidis 16S rRNA Genes and Use of 16S rRNA Gene Sequencing as a Molecular Subtyping Tool [PDF]

Journal of Clinical Microbiology, 2002
ABSTRACT We investigated the diversity of the primary sequences of 16S rRNA genes among Neisseria meningitidis strains (Men) and evaluated the use of this approach as a molecular subtyping tool. We aligned and compared a 1,417-bp fragment of the 16S rRNA gene from 264 Men strains of serogroups A, B, C, and
Claudio T, Sacchi, Anne M, Whitney, Michael W, Reeves, Leonard W, Mayer, Tanja, Popovic   +4 more
openaire   +2 more sources

Piezoelectric Surface Charge and Dynamic Stimulation Synergize to Promote Cardiac Myoblast Alignment and Maturation

Advanced Healthcare Materials, EarlyView.
Surface polarization of PVDF films combined with mechanical stimulation generates piezoelectric electrical cues that modulate cardiomyoblast behaviour. Non‐poled and poled PVDF substrates provide distinct electroactive microenvironments influencing cell adhesion, proliferation, and differentiation.
Rafaela M Meira, Sylvie Ribeiro, Senentxu Lanceros‐Mendez, Clarisse Ribeiro   +3 more
wiley   +1 more source

Sequence Comparison of Mitochondrial 16s rRNA Gene Segment in Penaeids

Asian Fisheries Science, 2007
A partial fragment of 16s rRNA mitochondrial gene was amplified by PCR from Penaeus monodon samples collected from the west and east coast regions of India. The amplified 520 bp of 16s rRNA mitochondrial gene segment of P.
M.S. SHEKHAR, G. GOPIKRISHNA, C. GOPAL, S.M. PILLAI, P. RAVICHANDRAN   +4 more
doaj   +1 more source

Polymorphism and gene conversion of the 16S rRNA genes in the multiple rRNA operons ofVibrio parahaemolyticus [PDF]

FEMS Microbiology Letters, 2005
The genome sequence of a strain of Vibrio parahaemolyticus holds 11 copies of rRNA operons (rrn) with identical 16S rRNA genes (rrs). Conversely, the species type strain contains two rrs classes differing in 10 nucleotide sites within a short segment of 25 bp.
González Escalona, Narjol, Romero Ormazábal, Jaime, Espejo Torres, Romilio   +2 more
openaire   +4 more sources

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

Advanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey, Harry Akligoh, Michael Finocchiaro, Abhishek Srihari Rampelli, Zongwei Wang, Aria F. Olumi, Tania Konry   +6 more
wiley   +1 more source

Williamsia faeni sp. nov., an actinomycete isolated from a hay meadow [PDF]

, 2010
The taxonomic status of an actinomycete isolated from soil collected from a hay meadow was determined using a polyphasic approach. The strain, designated N1350T, had morphological and chemotaxonomic properties consistent with its classification in the ...
Goodfellow, Michael, Jones, Amanda, Payne, Gail   +2 more
core   +1 more source

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source