Results 61 to 70 of about 2,798,395 (304)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Taxonomic and Characterization Methods of Streptomyces: A Review

Progress in Microbes and Molecular Biology, 2018
The 16S ribosomal RNA gene is the gold standard for taxonomic identification and phylogenetic study of most of the bacteria. However, the resolution of 16S rRNA gene is found to be insufficient to distinguish closely related Streptomyces species within ...
Jodi Woan-Fei Law, Kei-Xian Tan, Sunny Hei Wong, Nurul-Syakima Ab Mutalib, Learn-Han Lee   +4 more
doaj   +1 more source

Molecular detection of bacteria from a possible material oral origin in neonatal gastric aspirates obtained from complicated pregnancies [PDF]

, 2011
PhDIt has been suggested that periodontal disease, a disease that affects the supporting tissues of the teeth, represents a risk factor for adverse pregnancy outcomes.
Gonzales Marin, Cecilia
core   +4 more sources

Primer, Pipelines, Parameters: Issues in 16S rRNA Gene Sequencing

mSphere, 2021
In 16S rRNA gene sequencing, certain bacterial genera were found to be underrepresented or even missing in taxonomic profiles when using unsuitable primer combinations, outdated reference databases, or inadequate pipeline settings.
Isabel Abellan-Schneyder, Monica S. Matchado, Sandra Reitmeier, Alina Sommer, Zeno Sewald, Jan Baumbach, Markus List, Klaus Neuhaus   +7 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The fecal microbiome in dogs with acute diarrhea and idiopathic inflammatory bowel disease. [PDF]

, 2012
Recent molecular studies have revealed a highly complex bacterial assembly in the canine intestinal tract. There is mounting evidence that microbes play an important role in the pathogenesis of acute and chronic enteropathies of dogs, including ...
Toresson, Linda, Jörg M. Steiner (107366), Ivan Ivanov, Dillman, Enricka M., Enricka M Dillman, Ivanov, Ivan, Stefan Unterer (107353), Heimesaat, Markus M., García Mazcorro, José Francisco, Jan S. Suchodolski (107343), Romy M Heilmann, Markel, Melissa E., Enricka M. Dillman (107363), Linda Toresson (107370), Melissa E Markel, Markel, Melissa, Linda Toresson, Steiner, J��rg M., Audrey K. Cook (107368), Cook, Audrey K., Jan S Suchodolski, Minamoto, Yasushi, Jörg M Steiner, Garcia-Mazcorro, Jose F., Priyanka Kachroo, Scot E. Dowd (107356), Heilmann, Romy M., Dowd, Scot E., Yasushi Minamoto, Jose F. Garcia-Mazcorro (107351), Unterer, Stefan, Romy M. Heilmann (107355), Jose F Garcia-Mazcorro, Stefan Unterer, Yasushi Minamoto (107360), Scot E Dowd, Audrey K Cook, Ivan Ivanov (107359), Melissa E. Markel (107347), Priyanka Kachroo (107357), Kachroo, Priyanka, Steiner, Jörg M., Suchodolski, Jan S.   +42 more
core   +2 more sources

Evaluation of five bifidobacterium isolates as potential probiotics and genetic analysis of their ability to withstand oxidative stress [PDF]

, 2010
Includes bibliographical references (p. 102-112).The diverse microbiota of the human gastrointestinal tract plays a major role in the general health of humans.
Nonyane, Molati Albert
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Molecular biological methods for studying the gut microbiota : the EU human gut flora project [PDF]

, 2002
Seven European laboratories co-operated in a joint project (FAIR CT97-3035) to develop, refine and apply molecular methods towards facilitating elucidation of the complex composition of the human intestinal microflora and to devise robust methodologies ...
Vos, W.M., de, Collins, M.D., Welling, G.W., Loo, J., van, Blaut, M., Dore, J.   +5 more
core   +1 more source

Simultaneous measurement of 16S-rRNA and pre-16S-rRNA as a strategy to monitor clinical tuberculosis

Frontiers in Antibiotics
BackgroundCulture-based biomarkers of TB treatment response monitoring, e.g., Mycobacterial Growth Indicatory Tube (MGIT), are compromised when bacteria enter a non-replicating persister phase limiting the measurement of antibiotic efficacy and ...
Evelin Dombay, Wilber Sabiiti, Daniela Alferes de Lima Headley, M. Bonifác Légrády, Nina van Campen, Sanne Zweijpfennig, Martin J. Boeree, Derek J. Sloan, Stephen H. Gillespie   +8 more
doaj   +1 more source