Results 21 to 30 of about 41,844 (188)

Synthesis, physico-chemical properties of 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetohyd-razides

open access: yesФармацевтичний журнал, 2018
The value of the class of 1,2,4-triazole derivatives to create a low-toxic and highly active substances is huge. There are a lot of facts about the high biological activity among a number of substances.
A. A. Safonov
doaj   +1 more source

Novel Syntheses of Some 1, 2, 4‐Triazoles as Potent Bacteriocidal Agents [PDF]

open access: yesJournal of Chemistry, 2009
A facile syntheses of 4‐aryl‐5‐(isomeric pyridoyl)‐3H‐1, 2, 4‐triazoles as potent bacteriocidal agents are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P.aeruginosa. All compounds carrying 1, 2,
Ram Janam Singh, Dharmendra Kumar Singh
openaire   +2 more sources

Biological activity of the derivatives of 1,2,4-triazole

open access: yesФармацевтичний журнал, 2018
The rapid development of modern medicine and pharmacy leads to an increase in synthetic drugs. Thus, in the professional literature says that one of the perspective directions are searching for new biologically active compounds including heterocyclic ...
T. V. Kravchenko   +2 more
doaj   +1 more source

ACUTE TOXICITYOF 4-AMINO-5-(2-, 3-, 4-NITROPHENYL)-1,2,4-TRIAZOLE-3-THIONES AND ITS DERIVATIVES

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
The aim of research. In recent years both domestic and foreign scientists pay great attention to the modeling of biologically active substances that can become the basis of new original drugs in future.
М. O. Shcherbak   +2 more
doaj   +1 more source

1-[2-(4-Bromobenzyloxy)-2-phenylethyl]-1H-1,2,4-triazole

open access: yesActa Crystallographica Section E, 2008
In the molecule of the title compound, C17H16BrN3O, the triazole ring is oriented at dihedral angles of 6.14 (9)° and 82.08 (9)°, respectively, with respect to the phenyl and bromobenzene rings.
Tuncer Hökelek   +3 more
doaj   +1 more source

Synthesis of substituted 1, 2, 4-triazole derivatives by Microwave irradiation [PDF]

open access: yesIOSR Journal of Applied Chemistry, 2013
Various substituted Triazole-Thiol containing different functional group have been synthesized by microwave method. The title product 1-((3H-indol-2-ylamino) methyl)-4-phenyl-4, 5-dihydro-1H-1, 2, 4- triazole-3-thiol is synthesized by using amino benzothiazole.
Ashish Asrondkar   +2 more
openaire   +1 more source

Molecular docking, microwave-assisted synthesis, characterization, and preliminary evaluation of the anti-microbial activity of new sulfonamide derivatives of the 1, 2, 4-triazole-3-thiol ring system [PDF]

open access: yesPharmacia
A new sulfonamide derivative containing a 1,2,4-Triazole-3-thiol ring was synthesized and characterized using FT-IR and 1H-NMR. The microwave-assisted chemical synthesis of the 1,2,4-Triazole-3-thiol ring system resulted in good yield and purity.
Ali Abdulhadi Mosleh, Zainab A. Dakhel
doaj   +3 more sources

Evaluation Of Antioxidant Activity Of 1, 2, 4-Triazole Derivatives With Morpholine Moiety

open access: yesHacettepe University Journal of the Faculty of Pharmacy, 2022
The aim of the work was to study the antioxidant activity of 4-R-3- (morpholinomethyl)-4H-1,2,4-triazole-5-thioles and their alkyl derivatives in vitro using the method of non-enzymatic initiation of lipid peroxidation. Among the 45 compounds studied, 8 showed varying degrees of AOA.
SHCHERBYNA, Roman   +5 more
openaire   +2 more sources

The study of analgesic effect of 5-(furan-2-yl, 2-methylfuran-3-yl)-4-amino-1,2,4-triazole-3-thion derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Introduction. The nucleus of 1,2,4-triazole is the subject of close attention from a wide range of scientists because of numerous unique properties. Analyzing literary sources, it should be noted that there is a large amount of information devoted to the
D. M. Danilchenko
doaj   +1 more source

Combination of 1,2,3-triazole and 1,2,4-triazole frameworks for new high-energy and low-sensitivity compounds

open access: yesEnergetic Materials Frontiers, 2021
s: In this study, a series of energetic compounds based on C–C linked 1,2,3-triazole and 1,2,4-triazole were synthesized and characterized, i.e., 5-(5-nitro-2H-1,2,3-triazole-4-yl)-4H-1,2,4-triazole-3,4-diamine (compound 1), N-(3-amino-5-(5-nitro-2H-1,2 ...
Wenjing Yao   +4 more
doaj   +1 more source

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