Results 31 to 40 of about 97,768,533 (136)
The human milk oligosaccharide 2'-fucosyllactose alleviates liver steatosis, ER stress, and insulin resistance by reducing hepatic diacylglycerols and improving gut permeability in obese Ldlr-/-Leiden mice [PDF]
, 2022 Non-alcoholic fatty liver disease (NAFLD) is a complex multifactorial disorder that is associated with gut dysbiosis, enhanced gut permeability, adiposity and insulin resistance.
Attema, J. +11 more
core +1 more source
Human milk oligosaccharide 2'-fucosyllactose guards norovirus histo-blood group antigen co-factor binding site. [PDF]
J VirolHisto-blood group antigens (HBGAs) are critical polymorphic glycan co-factors required for most norovirus infections (1, 2). However, human milk oligosaccharide (HMO) 2’-fucosyllactose (2’-FL), a component of human breast milk and made up of related ...
Rudd PA +7 more
europepmc +2 more sources
Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis [PDF]
, 2019 ビフィズス菌におけるヒトへの適応進化を発見 --母乳オリゴ糖トランスポーターの獲得形質がビフィズスフローラ形成を促す--. 京都大学プレスリリース. 2019-09-05.The human gut microbiota established during infancy has persistent effects on health.
Lo Leggio, Leila +19 more
core +1 more source
, 2023 We explored the potential for the prebiotic oligofructose and prebiotic candidate 2'fucosyllactose, alone and in combination (50:50 blend) to induce physiologically relevant increases in neurotransmitter (γ-aminobutyric acid, serotonin, tryptophan, and ...
Robert Adrian Rastall +5 more
core +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Recombinant whole-cell biocatalysts are widely used for biotransformation of valuable products. However, some key enzymes involved in biotransformation processes are unstable and cannot be easily expressed in the functional form.
Yunjeong Park +15 more
doaj +1 more source
Molecules, 2022 Human milk is an intricate, bioactive food promoting infant health. We studied the composition of human milk samples collected over an 8-month lactation using 1H NMR metabolomics.
Maaria Kortesniemi +3 more
doaj +1 more source
Novel α-L-Fucosidases from a Soil Metagenome for Production of Fucosylated Human Milk Oligosaccharides. [PDF]
PLoS ONE, 2016 This paper describes the discovery of novel α-L-fucosidases and evaluation of their potential to catalyse the transglycosylation reaction leading to production of fucosylated human milk oligosaccharides.
Mateusz Lezyk +5 more
doaj +1 more source
, 2023 2′-Fucosyllactose (2′-FL), the most typical human milk oligosaccharide, is used as an additive in premium infant formula. Herein, we constructed two highly effective 2′-FL synthesis producers via a de novo GDP-fucose pathway from engineered Escherichia ...
Yihan Chen +13 more
core +1 more source
Differences in the content of human milk oligosaccharides between foremilk and hind milk
Food Bioengineering, 2023 Human milk oligosaccharides (HMOs) are the second largest carbohydrate component and the third largest nutrient after lactose, and their content and composition are related to the genetic characteristics of the mother, lactation period, geography, and ...
Zhiping Pu +6 more
doaj +1 more source
Determination of 2′-Fucosyllactose and Lacto-N-neotetraose in Infant Formula
Molecules, 2018 Human milk oligosaccharides (HMO) are the third most abundant solid component of human milk. It is likely that they are responsible for at least some of the benefits experienced by breast-fed infants.
Sean Austin +4 more
doaj +1 more source