Results 21 to 30 of about 97,768,533 (136)

Alleviation of Intestinal Inflammation by Oral Supplementation With 2-Fucosyllactose in Mice [PDF]

Frontiers in Microbiology, 2019
Milk oligosaccharides exert a prebiotic action that contributes to the development of the infant gut microbiota during lactation. Given that milk oligosaccharides remain intact after passage through stomach and small intestine, they can potentially ...
Thomas Grabinger, Jesus Francisco Glaus Garzon, Martin Hausmann, Annelies Geirnaert, Christophe Lacroix, Thierry Hennet   +5 more
doaj   +2 more sources

Inulin-type fructans and 2’fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial [PDF]

, 2023
There is increasing interest in the bi-directional relationship existing between the gut and brain and the effects of both oligofructose and 2'fucosyllactose to alter microbial composition and mood state.
Robert A. Rastall, Claire M. Williams, Jackson, Peter P. J., Rastall, Robert A., Jessica van Harsselaar, Stephan Theis, Peter PJ. Jackson, Williams, Claire M., Anisha Wijeyesekera, Wijeyesekera, Anisha, van Harsselaar, Jessica, Theis, Stephan   +11 more
core   +1 more source

Safety of the extension of use of 2′‐fucosyllactose (2′‐FL) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, 2023
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of the extension of use of 2′‐fucosyllactose (2′‐FL) as a novel food (NF) pursuant to ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Miguel Prieto Maradona, Rosangela Marchelli, Monika Neuhäuser‐Berthold, Carmen Peláez, Morten Poulsen, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Paolo Colombo, Estefanía Noriega Fernández, Helle Katrine Knutsen   +29 more
doaj   +1 more source

De novo 2′‐fucosyllactose bioproduction through modular engineering of a novel Escherichia coli K12‐derived strain

Food Bioengineering, 2023
The most abundant human milk oligosaccharide 2′‐fucosyllactose (2′‐FL) is a valuable component that has gained significant attention from the food industry.
Chunyu Ma, Chunyue Zhang, Liqiang Fan, Chen Deng, Liming Zhao   +4 more
doaj   +1 more source

Safety of 2′‐fucosyllactose (2’‐FL) produced by a derivative strain (Escherichia coli SGR5) of E. coli W (ATCC 9637) as a Novel Food pursuant to Regulation (EU) 2015/2283

EFSA Journal, 2023
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 2′‐fucosyllactose (2’‐FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Miguel Prieto Maradona, Rosangela Marchelli, Monika Neuhäuser‐Berthold, Carmen Peláez, Morten Poulsen, Josef Rudolf Schlatter, Alexandros Siskos, Henk vanLoveren, Paolo Colombo, Estefanía Noriega Fernández, Helle Katrine Knutsen   +29 more
doaj   +1 more source

Regulation of hBD-2, hBD-3, hCAP18/LL37, and Proinflammatory Cytokine Secretion by Human Milk Oligosaccharides in an Organotypic Oral Mucosal Model

Pathogens, 2021
Human milk oligosaccharides (HMOs), the third largest solid fraction in human milk, can modulate inflammation through Toll-like receptor signaling, but little is known about their immunomodulatory potential in the oral cavity.
Ulvi K. Gürsoy, Krista Salli, Eva Söderling, Mervi Gürsoy, Johanna Hirvonen, Arthur C. Ouwehand   +5 more
doaj   +1 more source

Effects of Different Human Milk Oligosaccharides on Growth of Bifidobacteria in Monoculture and Co-culture With Faecalibacterium prausnitzii

Frontiers in Microbiology, 2020
Human milk oligosaccharides (hMOs) are important bioactive components in mother’s milk contributing to infant health by supporting colonization and growth of gut microbes.
Lianghui Cheng, Mensiena B. G. Kiewiet, Madelon J. Logtenberg, Andre Groeneveld, Arjen Nauta, Henk A. Schols, Marthe T. C. Walvoort, Hermie J. M. Harmsen, Paul de Vos   +8 more
doaj   +1 more source

Selective proliferation of intestinal Barnesiella under fucosyllactose supplementation in mice [PDF]

, 2014
The oligosaccharides 2-fucosyllactose and 3-fucosyllactose are major constituents of human breast milk but are not found in mouse milk. Milk oligosaccharides have a prebiotic action, thus affecting the colonisation of the infant intestine by microbiota ...
Hennet, Thierry, Chassard, Christophe, Weiss, Gisela A, Weiss, Gisela A., Chassard C, Hennet T, Weiss GA   +6 more
core   +1 more source

2′-Fucosyllactose Ameliorates Oxidative Stress Damage in d-Galactose-Induced Aging Mice by Regulating Gut Microbiota and AMPK/SIRT1/FOXO1 Pathway

Foods, 2022
The imbalance of reactive oxygen species is the main cause in aging, accompanied by oxidative stress. As the most abundant in human milk oligosaccharides (HMOs), 2′-Fucosyllactose (2′-FL) has been confirmed to have great properties in immunity regulation
Jin Wang, Jia-Qiang Hu, Yu-Jie Song, Jia Yin, Yuan-Yi-Fei Wang, Bo Peng, Bo-Wei Zhang, Jing-Min Liu, Lu Dong, Shuo Wang   +9 more
doaj   +1 more source

The Milk Active Ingredient, 2′-Fucosyllactose, Inhibits Inflammation and Promotes MUC2 Secretion in LS174T Goblet Cells In Vitro

Foods, 2023
In several mice inflammatory models, human milk oligosaccharides (HMOs) were shown to protect the intestinal barrier by promoting mucin secretion and suppressing inflammation. However, the functions of the individual HMOs in enhancing mucin expression in
Qianqian Yao, Huiying Li, Yanan Gao, Nan Zheng, Véronique Delcenserie, Jiaqi Wang   +5 more
doaj   +1 more source