Results 11 to 20 of about 9,813 (135)

Thymoquinone: Hydroxypropyl-β-cyclodextrin Loaded Bacterial Cellulose for the Management of Wounds

Pharmaceutics, 2022
The need for more advantageous and pharmaceutically active wound dressings is a pressing matter in the area of wound management. In this study, we explore the possibility of incorporating thymoquinone within bacterial cellulose, utilising cyclodextrins ...
Sam Swingler, Abhishek Gupta, Hazel Gibson, Marek Kowalczuk, Grazyna Adamus, Wayne Heaselgrave, Iza Radecka   +6 more
doaj   +1 more source

The improved photostability of naproxen in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]

Hemijska Industrija, 2015
The aim of this work was the preparation of the inclusion complex of naproxen with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) in order to improve the physical and chemical properties of naproxen.
Ilić-Stojanović Snežana S., Nikolić Vesna D., Nikolić Ljubiša B., Zdravković Aleksandar S., Kapor Agneš J., Popsavin Mirjana M., Petrović Slobodan D.   +6 more
doaj   +1 more source

Improving Lurasidone Hydrochloride’s Solubility and Stability by Higher-Order Complex Formation with Hydroxypropyl-β-cyclodextrin

Pharmaceutics, 2023
The biopharmaceutical classification system groups low-solubility drugs into two groups: II and IV, with high and low permeability, respectively. Most of the new drugs developed for common pathologies present solubility issues.
María Elena Gamboa-Arancibia, Nelson Caro, Alexander Gamboa, Javier Octavio Morales, Jorge Enrique González Casanova, Diana Marcela Rojas Gómez, Sebastián Miranda-Rojas   +6 more
doaj   +1 more source

Hydroxypropyl-β-cyclodextrin as an effective carrier of curcumin – piperine nutraceutical system with improved enzyme inhibition properties

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
The nutraceutical system of curcumin-piperine in 2-hydroxypropyl-β-cyclodextrin was prepared by using the kneading technique. Interactions between the components of the system were defined by X-ray powder diffraction (XRPD), differential scanning ...
Anna Stasiłowicz, Ewa Tykarska, Kornelia Lewandowska, Maciej Kozak, Andrzej Miklaszewski, Joanna Kobus-Cisowska, Daria Szymanowska, Tomasz Plech, Jacek Jenczyk, Judyta Cielecka-Piontek   +9 more
doaj   +1 more source

Buccal Resveratrol Delivery System as a Potential New Concept for the Periodontitis Treatment

Pharmaceutics, 2021
The health benefits of resveratrol have been proven to inhibit the development of numerous diseases. A frequent limitation in its use is a low bioavailability stemming from a poor solubility and fast enterohepatic metabolism.
Magdalena Paczkowska-Walendowska, Jakub Dvořák, Natalia Rosiak, Ewa Tykarska, Emilia Szymańska, Katarzyna Winnicka, Marek A. Ruchała, Judyta Cielecka-Piontek   +7 more
doaj   +1 more source

Electrochemical Quantitative Assessment of Labetalol Hydrochloride in Pure Form and Combined Pharmaceutical Formulations

Acta Chimica Slovenica, 2020
This work describes how to utilize the electrochemical technique to determine labetalol hydrochloride (Lab) in pure form and combined pharmaceutical formulation for quality control purposes.
Maissa Yacoub Salem, Nagiba Yehia Hassan, Yasmin Mohamed Fayez, Samah Abd-EL Sabour Mohamed, ENAS Shabaan ALI   +4 more
doaj   +1 more source

Antimicrobial silicone skin adhesives facilitated by controlled octenidine release from glycerol compartments

International Journal of Smart and Nano Materials, 2023
For improved wound healing, antimicrobial adhesives are one path forward. However, with the current challenge of bacterial resistance, it is essential to choose the included drug carefully.
V. Chiaula, J. Jeppe Madsen, F.B. Madsen, P. Mazurek, A. C. Nielsen, A. L. Skov   +5 more
doaj   +1 more source

2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent. [PDF]

PLoS ONE, 2015
2-Hydroxypropyl-β-cyclodextrin (HP-β-CyD) is a cyclic oligosaccharide that is widely used as an enabling excipient in pharmaceutical formulations, but also as a cholesterol modifier.
Masako Yokoo, Yasushi Kubota, Keiichi Motoyama, Taishi Higashi, Masatoshi Taniyoshi, Hiroko Tokumaru, Rena Nishiyama, Yoko Tabe, Sakiko Mochinaga, Akemi Sato, Naoko Sueoka-Aragane, Eisaburo Sueoka, Hidetoshi Arima, Tetsumi Irie, Shinya Kimura   +14 more
doaj   +1 more source

The Cholesterol Transport Inhibitor U18666A Interferes with Pseudorabies Virus Infection

Viruses, 2022
Many viruses require the maintenance of lysosomal cholesterol homeostasis for a successful infection; however, the role of lysosomal cholesterol homeostasis in the alphaherpesvirus life cycle is not clear.
Byeongwoon Song
doaj   +1 more source

Preparation, characterization and in vitro dissolution study of Nitrazepam: Cyclodextrin inclusion complex

Journal of Pharmacy and Bioallied Sciences, 2012
The objectives of this research were to prepare and characterize inclusion complexes of Nitrazepam with Hydroxypropyl-β-cyclodextrin (HPβCD) and Sulfobutyl ether β-cyclodextrin (SBEβCD) to study the effect of complexation on the dissolution rate of ...
J S Patel, R P Patel
doaj   +1 more source