Results 11 to 20 of about 18,161,920 (183)

The improved photostability of naproxen in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]

Hemijska Industrija, 2015
The aim of this work was the preparation of the inclusion complex of naproxen with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) in order to improve the physical and chemical properties of naproxen.
Ilić-Stojanović Snežana S., Nikolić Vesna D., Nikolić Ljubiša B., Zdravković Aleksandar S., Kapor Agneš J., Popsavin Mirjana M., Petrović Slobodan D.   +6 more
doaj   +2 more sources

Enhancement of norfloxacin solubility via inclusion complexation with β-cyclodextrin and its derivative hydroxypropyl-β-cyclodextrin

Asian Journal of Pharmaceutical Sciences, 2016
The objectives of the study were to investigate the effects of β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD) on the solubility and dissolution rate of norfloxacin prepared using three different methods, at drug to cyclodextrin weight ...
Gabriel Onn Kit Loh, Yvonne Tze Fung Tan, Kok-Khiang Peh   +2 more
doaj   +2 more sources

The thermodynamic study of p-methoxycinnamic acid inclusion complex formation, using β-cyclodextrin and hydroxypropyl-β-cyclodextrin [PDF]

, 2021
Objectives: Cyclodextrin’s ability to form an inclusion complex with a guest molecule is a function of two factors. The first is steric and depends on the relative size of cyclodextrin cavity to the guest molecule, while the second is the thermodynamic ...
Dewi Isadiartuti, Juni Ekowati, Noorma Rosita, Achmad Syahrani, Toetik Ariyani   +4 more
core   +1 more source

Thymoquinone: Hydroxypropyl-β-cyclodextrin Loaded Bacterial Cellulose for the Management of Wounds

Pharmaceutics, 2022
The need for more advantageous and pharmaceutically active wound dressings is a pressing matter in the area of wound management. In this study, we explore the possibility of incorporating thymoquinone within bacterial cellulose, utilising cyclodextrins ...
Sam Swingler, Abhishek Gupta, Hazel Gibson, Marek Kowalczuk, Grazyna Adamus, Wayne Heaselgrave, Iza Radecka   +6 more
doaj   +1 more source

Improving Lurasidone Hydrochloride’s Solubility and Stability by Higher-Order Complex Formation with Hydroxypropyl-β-cyclodextrin

Pharmaceutics, 2023
The biopharmaceutical classification system groups low-solubility drugs into two groups: II and IV, with high and low permeability, respectively. Most of the new drugs developed for common pathologies present solubility issues.
María Elena Gamboa-Arancibia, Nelson Caro, Alexander Gamboa, Javier Octavio Morales, Jorge Enrique González Casanova, Diana Marcela Rojas Gómez, Sebastián Miranda-Rojas   +6 more
doaj   +1 more source

Hydroxypropyl-β-cyclodextrin as an effective carrier of curcumin – piperine nutraceutical system with improved enzyme inhibition properties

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
The nutraceutical system of curcumin-piperine in 2-hydroxypropyl-β-cyclodextrin was prepared by using the kneading technique. Interactions between the components of the system were defined by X-ray powder diffraction (XRPD), differential scanning ...
Anna Stasiłowicz, Ewa Tykarska, Kornelia Lewandowska, Maciej Kozak, Andrzej Miklaszewski, Joanna Kobus-Cisowska, Daria Szymanowska, Tomasz Plech, Jacek Jenczyk, Judyta Cielecka-Piontek   +9 more
doaj   +1 more source

Buccal Resveratrol Delivery System as a Potential New Concept for the Periodontitis Treatment

Pharmaceutics, 2021
The health benefits of resveratrol have been proven to inhibit the development of numerous diseases. A frequent limitation in its use is a low bioavailability stemming from a poor solubility and fast enterohepatic metabolism.
Magdalena Paczkowska-Walendowska, Jakub Dvořák, Natalia Rosiak, Ewa Tykarska, Emilia Szymańska, Katarzyna Winnicka, Marek A. Ruchała, Judyta Cielecka-Piontek   +7 more
doaj   +1 more source

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]

, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
Jones, A., Michael P. Barrett, Peter G E Kennedy, Bradley Barbara, Bradley, Barbara, Barrett, M. P., McCabe Christopher, Peter G. E. Kennedy, Bradley, B., Rodgers, Jean, Gettinby, George, Gettinby George, Kennedy Peter G. E., McCabe, Chris, Amy Jones, Kennedy, Peter G. E., Barrett, Michael P., Michael P Barrett, Kennedy, Peter G.E., George Gettinby, Gibaud, Stephane, Barbara Bradley, McCabe, C., Mccabe, Christopher, Jean Rodgers, Kennedy, P. G. E., Gibaud, S., Stéphane Gibaud, Rodgers, J., Rodgers Jean, Jones Amy, Jones, Amy, Christopher McCabe, Barrett Michael P., Gibaud Stéphane, Gettinby, G.   +35 more
core   +1 more source

Electrochemical Quantitative Assessment of Labetalol Hydrochloride in Pure Form and Combined Pharmaceutical Formulations

Acta Chimica Slovenica, 2020
This work describes how to utilize the electrochemical technique to determine labetalol hydrochloride (Lab) in pure form and combined pharmaceutical formulation for quality control purposes.
Maissa Yacoub Salem, Nagiba Yehia Hassan, Yasmin Mohamed Fayez, Samah Abd-EL Sabour Mohamed, ENAS Shabaan ALI   +4 more
doaj   +1 more source

Hyperglycosylated LAMP1 is regulated by 2-hydroxypropyl-β-cyclodextrin treatment.

, 2020
A. LAMP1 and β-tubulin Western blot of total cerebellar extract from 7-week-old Npc1+/+ and Npc1−/− mice treated with either 2-hydroxypropyl-β-cyclodextrin (HPβCD) or the vehicle control (PBS) every 3 days starting at 3 weeks of age. B.
Antony Cougnoux (8198772), Anna T. Lyons (8379309), Christopher A. Wassif (125679), Caitlin Sojka (8379306), Niamh X. Cawley (8379303), Elena‐Raluca Nicoli (8379312), Forbes D. Porter (125687)   +6 more
core   +1 more source