Results 21 to 30 of about 18,161,920 (183)

Antimicrobial silicone skin adhesives facilitated by controlled octenidine release from glycerol compartments

International Journal of Smart and Nano Materials, 2023
For improved wound healing, antimicrobial adhesives are one path forward. However, with the current challenge of bacterial resistance, it is essential to choose the included drug carefully.
V. Chiaula, J. Jeppe Madsen, F.B. Madsen, P. Mazurek, A. C. Nielsen, A. L. Skov   +5 more
doaj   +1 more source

Video_4_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent. [PDF]

PLoS ONE, 2015
2-Hydroxypropyl-β-cyclodextrin (HP-β-CyD) is a cyclic oligosaccharide that is widely used as an enabling excipient in pharmaceutical formulations, but also as a cholesterol modifier.
Masako Yokoo, Yasushi Kubota, Keiichi Motoyama, Taishi Higashi, Masatoshi Taniyoshi, Hiroko Tokumaru, Rena Nishiyama, Yoko Tabe, Sakiko Mochinaga, Akemi Sato, Naoko Sueoka-Aragane, Eisaburo Sueoka, Hidetoshi Arima, Tetsumi Irie, Shinya Kimura   +14 more
doaj   +1 more source

Ensemble Simulations of 2-Hydroxypropyl-β-cyclodextrin Complexes with All-Atom Molecular Dynamics Simulations

, 2022
2-Hydroxypropyl-β-cyclodextrins (HP-β-CDs) ability to form inclusion complexes with lipophilic compounds is important both to treat Niemann Pick Type C disease and as part of a more general drug-formulation as a drug carrier.
Simon, Nygaard-Thomsen, Jeppe Tværmose, Munk, Thorleif Riis Bay, Stokholm, Casper, Steinmann, Mads Rosander, Langhorn   +4 more
core   +1 more source

The Cholesterol Transport Inhibitor U18666A Interferes with Pseudorabies Virus Infection

Viruses, 2022
Many viruses require the maintenance of lysosomal cholesterol homeostasis for a successful infection; however, the role of lysosomal cholesterol homeostasis in the alphaherpesvirus life cycle is not clear.
Byeongwoon Song
doaj   +1 more source

Preparation, characterization and in vitro dissolution study of Nitrazepam: Cyclodextrin inclusion complex

Journal of Pharmacy and Bioallied Sciences, 2012
The objectives of this research were to prepare and characterize inclusion complexes of Nitrazepam with Hydroxypropyl-β-cyclodextrin (HPβCD) and Sulfobutyl ether β-cyclodextrin (SBEβCD) to study the effect of complexation on the dissolution rate of ...
J S Patel, R P Patel
doaj   +1 more source

Table_1_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.docx

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Image_7_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.tif

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Interactions between 4-thiothymidine and water-soluble cyclodextrins: Evidence for supramolecular structures in aqueous solutions

Beilstein Journal of Organic Chemistry, 2016
Since several years the inclusion of organic compounds (guests) within the hydrophobic cavity (host) of cyclodextrins (CDs) has been the subject of many investigations.
Vito Rizzi, Sergio Matera, Paola Semeraro, Paola Fini, Pinalysa Cosma   +4 more
doaj   +1 more source

Preparation, Characterization and Molecular Dynamics Simulation of Rutin–Cyclodextrin Inclusion Complexes

Molecules, 2023
Rutin is a natural flavonoid that carries out a variety of biological activities, but its application in medicine and food is limited by its water solubility.
Chaokang Chang, Meng Song, Mingxing Ma, Jihong Song, Fengyi Cao, Qi Qin   +5 more
doaj   +1 more source