Results 31 to 40 of about 18,161,920 (183)

Image_8_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.tif

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Characterization of an aryl piperazine/2-hydroxypropyl-β-cyclodextrin association, a complex with antidiabetic potential

Results in Chemistry, 2020
This study explores the molecular association between 4-(thiophen-2-yl)-1-(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)butan-1-one (RTC1), an antidiabetic compound recently reported by our research group with challenging aqueous solubility, and 2 ...
R. Devine, D.S.D. Martin, G.K. Kinsella, J.B.C. Findlay, J.C. Stephens   +4 more
doaj   +1 more source

Nano-Spray-Dried Levocetirizine Dihydrochloride with Mucoadhesive Carriers and Cyclodextrins for Nasal Administration

Pharmaceutics, 2023
Antihistamines such as levocetirizine dihydrochloride (LC) are commercially used in oral tablets and oral drops to reduce allergic symptoms. In this study, LC was nano-spray-dried using three mucoadhesive polymers and four cyclodextrin species to form ...
Mirella Mirankó, Judit Tóth, Csilla Bartos, Rita Ambrus, Tivadar Feczkó   +4 more
doaj   +1 more source

Video_2_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Video_3_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source

Solubility enhancement of etoricoxib using inclusion complexation with cyclodextrins: formulation of oro dispersible tablets by QbD approach

Journal of Applied Pharmaceutical Research
Background: The work was intended to enhance etoricoxib's solubility and dissolution rate and then develop oro-dispersible tablets for faster onset of action. Methodology: Inclusion complexes (ICs) of the drug were obtained with β-cyclodextrin (β-CD) and
Anjan Kumar Mahapatra, Siddharth Dora, Sanatan Parida, Usharani Bal, Bandana Rani Jena, Madhusmita Lenka   +5 more
doaj   +1 more source

Maternal and Foetal Cardiovascular Effects of the Anaesthetic Alfaxalone in 2-Hydroxypropyl-β-cyclodextrin in the Pregnant Ewe

The Scientific World Journal, 2013
The objective of this study was to determine the pharmacodynamics effects of the anaesthetic alfaxalone in 2-hydroxypropyl-β-cyclodextrin in pregnant sheep after the intravenous injection of a 2 mg/kg weight dose.
Anna Andaluz, Laura Santos, Félix García, Rosa I. Ferrer, Laura Fresno, Xavier Moll   +5 more
doaj   +1 more source

Quantitative prediction of the bitterness of atomoxetine hydrochloride and taste-masked using hydroxypropyl-β-cyclodextrin: A biosensor evaluation and interaction study

Asian Journal of Pharmaceutical Sciences, 2020
The bitterness of a drug is a major challenge for patient acceptability and compliance, especially for children. Due to the toxicity of medication, a human taste panel test has certain limitations.
Shuying Li, Ying Zhang, Abdur Rauf Khan, Shuwang He, Yingxin Wang, Jiangkang Xu, Guangxi Zhai   +6 more
doaj   +1 more source

Improvement of stilbenoid production by 2-hydroxypropyl-β-cyclodextrin in white mulberry (Morus alba L.) callus cultures

, 2018
Mulberroside A, oxyresveratrol and resveratrol, commonly found in Morus alba L., are potent anti-aging phytostilbenes. In this study, the effect of the addition of 2-hydroxypropyl-β-cyclodextrin on the levels of phytostilbenes in M.
Tharita Kitisripanya (6006191), Hiroyuki Tanaka (9428), Jukrapun Komaikul (6006188), Kittisak Likhitwitayawuid (2721406), Waraporn Putalun (6006194), Boonchoo Sritularak (4722669)   +5 more
core   +1 more source

Video_1_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov

, 2021
Lifestyle- and genetically induced disorders related to disturbances in cholesterol metabolism have shown the detrimental impact of excessive cholesterol levels on a plethora of pathological processes such as inflammation.
Dimitris Kapsokalyvas (11305455), Dieter Lütjohann (186632), Marit Westerterp (6178532), Tom Houben (3185082), David Leake (10747299), Marion J. J. Gijbels (9501749), Joost J. F. P. Luiken (4390150), Ronit Shiri-Sverdlov (186636), Tulasi Yadati (11145288), Jogchum Plat (302633), Robbin de Kruijf (11305452), Marc van Zandvoort (8349135)   +11 more
core   +1 more source