Results 71 to 80 of about 26,508 (195)

Formulation and characterization of biocompatible and stable I.V. itraconazole nanosuspensions stabilized by a new stabilizer polyethylene glycol-poly(β-Benzyl-L-aspartate) (PEG-PBLA) [PDF]

, 2017
Amphiphilic block copolymers, PEG-PBLA with different molecular weights, were synthesized and used as new stabilizers for Itraconazole nannosuspensions (ITZ-PBLA-Nanos).
Cao, Y, Chen, D, Han, J, Li, M, Li, X, Pu, X, Wang, H, Wei, Z, Yin, L, Zong, L   +9 more
core   +2 more sources

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

Cavity Closure of 2-Hydroxypropyl-β-Cyclodextrin: Replica Exchange Molecular Dynamics Simulations. [PDF]

Polymers (Basel), 2019
2-Hydroxypropyl-β-cyclodextrin (HPβCD) has unique properties to enhance the stability and the solubility of low water-soluble compounds by inclusion complexation.
Kerdpol K, Kicuntod J, Wolschann P, Mori S, Rungnim C, Kunaseth M, Okumura H, Kungwan N, Rungrotmongkol T.   +8 more
europepmc   +2 more sources

Simvastatin dengan Senyawa Turunan Β-Siklodextrin [PDF]

This study aims to determine the profile of the inclusion complex formed between simvastatin and β-cyclodextrin and its derivatives. To determine the level of stability and determine the solubility level of the inclusion complex formed between ...
Cristy, Devina Wahyu Astaning, Harmastuti, Nuraini, Mardiyono, Mardiyono   +2 more
core   +2 more sources

Anaesthetic management of a patent ductus arteriosus (PDA) occlusion using an Amplatz canine duct occluder (ACDO) in a dog

, 2020
Patent ductus arteriosus (PDA) is one of the most common diagnosed congenital disease in dogs that usually causes heart failure and death unless corrected at a young age. A 2.5-year-old female intact Coton de Tuléar was referred and diagnosed with a left
Binetti, Anna, Bosmans, Tim, Schauvliege, Stijn, Smets, Pascale   +3 more
core   +1 more source

mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. [PDF]

, 2018
Metabotropic glutamate receptor 5 (mGluR5) antagonism inhibits cocaine self-administration and reinstatement of drug-seeking behavior. However, the cellular and molecular mechanisms underlying this action are poorly understood.
Bi, Guo-Hua, Gardner, Eliot L, He, Yi, Jordan, Chloe J, Li, Jie, Li, Xia, Peng, Xiao-Qing, Xi, Zheng-Xiong, Yang, Hong-Ju, Zhang, Hai-Ying   +9 more
core   +2 more sources

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

Advanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang, Wen Zhou, Haotian Xue, Wenjun Xue, Guangping Gao, Bing Zhu, Hongyuan Song, Qingqiang Xu, Jing Zhao, Wei Shen   +9 more
wiley   +1 more source

Voltammetric Investigation of Inclusion Complexes of the Selected Succinimides with β-cyclodextrin and (2-hydroxypropyl)-β-cyclodextrin

Acta Chimica Slovenica, 2019
The inclusion complexes of the selected, potentially biologically active, succinimides with β-cyclodextrin (bCD) and (2-hydroxypropyl)-β-cyclodextrin (HPbCD) were prepared.
Jelena Lović, Milka Avramov Ivić, Bojan Božić, Jelena Lađarević, Dušan Mijin   +4 more
doaj   +1 more source

Sugar‐Armored Pesticides: Self‐Assembled System for Enhanced Foliar Adhesion and Sustained Delivery of Hydrophobic Antimicrobials Against Bacterial Diseases

Advanced Science, EarlyView.
This study develops a sugar‐armored, self‐assembled pesticide delivery system that enhances foliar adhesion, provides sustained release, effectively disrupts biofilms, and demonstrates superior bactericidal activity for improved disease control.
Jinghan Yang, Juan Liu, Xiaohui Wang, Peiyi Wang   +3 more
wiley   +1 more source

Fluorescence Quenching and Inclusion Complex Analysis of Propranolol and [Beta]-Cyclodextrin [PDF]

, 2011
Mentor: Maria BohorquezDrake ...
Izzi, Matteo
core   +1 more source