Results 71 to 80 of about 5,480 (215)

An optimized molecular inclusion complex of diferuloylmethane: enhanced physical properties and biological activity

International Journal of Nanomedicine, 2012
Qunyou Tan,1,* Yi Li,2–4,* Jianyong Wu,2,* Hu Mei,5 Chunjing Zhao,3 Jingqing Zhang21Department of Thoracic Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, 2Medicine Engineering Research Center ...
Tan Q, Li Y, Wu J, Mei H, Zhao C, Zhang J   +5 more
doaj  

Effects of cyclosporin on cholesterol 27-hydroxylation and LDL receptor activity in HepG2 cells.

Journal of Lipid Research, 1996
The hypothesis that mitochondrial sterol 27-hydroxylase plays a role in the sterol-mediated down-regulation of LDL receptor activity was evaluated in HepG2 cells. 27-Hydroxycholesterol was found to be more potent at suppressing LDL receptor activity than
D A Winegar, J A Salisbury, S S Sundseth, R L Hawke   +3 more
doaj   +1 more source

MODIFICATION OF THE RELEASE OF DIPYRIDAMOLE FROM CERTAIN POLYMERIC SYSTEMS [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2004
The objective of the present study is to modify the release of dipyridamole (DIP); whichhas a pH dependant solubility in order to overcome its irregular and incomplete absorptionfrom the gastrointestinal tract.
Ali Abdel-Rhaman, Mahrous Ahmed, Amany Abdel-Rheem, Ahmed Aboutaleb   +3 more
doaj   +1 more source

فرآورده‌های زيستی فعال ضد سرطان و سيتوتوکسيک نرم‌تنان خليج فارس [PDF]

, 2009
زمينه: در دهه گذشته، پژوهش های پيش بالينی برای جداسازی و مکانيسم اثر ترکيبات دريايی رشد پرشتابی يافته اند و از آن جا که 60 درصد از داروهای مورد استفاده در درمان سرطان، منشاء طبيعی دارند، دور از ذهن نخواهد بود که به دريا همچون گستره‎ای فراهم برای يافت ...
بوالخیر, امیرضا, نبی پور, ایرج, نجفی, آرزو   +2 more
core  

An acetylcholine alpha7 positive allosteric modulator rescues a schizophrenia-associated brain endophenotype in the 15q13.3 microdeletion, encompassing CHRNA7 [PDF]

, 2016
The 15q13.3 microdeletion copy number variation is strongly associated with schizophrenia and epilepsy. The CHRNA7 gene, encoding nicotinic acetylcholine alpha 7 receptors (nAChA7Rs), is hypothesized to be one of the main genes in this deletion causing ...
Bastlund, Jesper Frank, Becker, Robert, Didriksen, Michael, Gass, Natalia, Meyer-Lindenberg, Andreas, Sartorius, Alexander, Schwarz, Adam J., Stensbøl, Tine Bryan, Weber-Fahr, Wolfgang   +8 more
core   +1 more source

Inclusional complex study between 6-p-toluidinylnaphthalene-2-sulfonate and 2-hydroxypropyl-beta-cyclodextrin

Journal of Biochemical and Biophysical Methods, 2002
6-p-Toluidinylnaphthalene-2-sulfonate (TNS) is used as a fluorescent probe for exploring hydrophobic regions of several biological substances, such as proteins, and studying solution state folding behaviour. The current study examines the complexation of TNS with 2-hydroxypropyl-beta-cyclodextrin (HPbetaCD) in aqueous solution, mainly by ultraviolet ...
Dotsikas, Y, Loukas, YL
openaire   +3 more sources

Harnessing Fatty Acid By‐Products for Diabetes Management: Insights From Nutritional and Biological Research

eFood, Volume 7, Issue 3, June 2026.
Bioactive fatty acids from agro‐industrial byproducts are highlighted as a promising avenue for managing diabetes in this review, which aims to develop targeted interventions for optimal utilization and therapeutic benefits. ABSTRACT Diabetes mellitus (DM), influenced by multifaceted factors, creates a complex imbalance within the body. Nutrition plays
Youssef Elouafy, Abdelaali Balahbib, Meriem El Fessikh, Saïd Gharby, Nasreddine El Omari, Waleed Al Abdulmonem, Gokhan Zengin, Abdelhakim Bouyahya   +7 more
wiley   +1 more source

Modification of paclitaxel-loaded solid lipid nanoparticles with 2-hydroxypropyl-β-cyclodextrin enhances absorption and reduces nephrotoxicity associated with intravenous injection

International Journal of Nanomedicine, 2015
Jong-Suep Baek,* Ju-Heon Kim,* Jeong-Sook Park, Cheong-Weon Cho College of Pharmacy and Institute of Drug Research and Development, Chungnam National University, Daejeon, South Korea *These authors contributed equally to this work Background ...
Baek JS, Kim JH, Park JS, Cho CW
doaj  

Development of Functional Composite Edible Films or Coatings for Fruits Preservation with Addition of Pomace Oil-Based Nanoemulsion for Enhanced Barrier Properties and Caffeine for Enhanced Antioxidant Activity

Molecules
The aim of this study was to develop functional composite edible films or coatings for fruit preservation by the addition of bioactive components in combinations that have not yet been thoroughly studied, according to the relevant literature.
Angelos-Panagiotis Bizymis, Virginia Giannou, Constantina Tzia   +2 more
doaj   +1 more source

Patient derived xenograft models of small-cell lung cancer provide molecular insights into mechanisms of chemotherapy cross-resistance [PDF]

, 2018
Small Cell Lung Cancer (SCLC) is a highly aggressive neuroendocrine tumor with a 5% survival rate over 5 years. Though SCLC comprises 13% of all cases of lung cancer the median survival time of 14.5 months has seen little improvement over the last four ...
Myers, David Thomas
core