Results 51 to 60 of about 5,480 (215)

Host-guest interactions between cyclodextrins and surfactants with functional groups at the end of the hydrophobic tail [PDF]

, 2017
The aim of this work was to investigate the influence of the incorporation of substituents at the end of the hydrophobic tail on the binding of cationic surfactants to α-, β-, and -cyclodextrins.
Angulo Álvarez, Manuel, Carmona Asenjo, Ana Teresa, López López, Manuel, López-Cornejo, María del Pilar, Martín, Victoria I., Moyá Morán, María Luisa, Márquez Cruz, Antonio Marcial, Ostos Marcos, Francisco José   +7 more
core   +1 more source

Development of immunocompetent models for primary and metastatic ER+ breast cancer

Animal Models and Experimental Medicine, EarlyView.
This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull, Jody Hazlett, Emily Schulpen, Sophie Tunnicliffe, Alexander D. McLellan, Anita K. Dunbier   +5 more
wiley   +1 more source

EVALUATION OF THE EFFECT OF POLYVINYLPYRROLIDONE AND CERTAIN ENHANCERS ON THE PERMEATION OF CORTICOSTERONE FROM TRANSDERMAL DELIVERY SYSTEMS: (PART II) [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2003
The purpose of the present study was to evaluate the permeation profiles of unlabeledcorticosterone (CS) drug from gels and adhesive patches as transdermal delivery systems.
Dalia Shaker, Eman El-leithy, Abdel Ghanem, Fahima Hashem   +3 more
doaj   +1 more source

Validation and Application of an HPLC–UV Method for the Quantification of 3‐O‐Methylquercetin in Nasal Mucosa

ELECTROPHORESIS, EarlyView.
This study improved an HPLC–UV method for quantifying 3‐O‐methylquercetin in porcine nasal mucosa following ICH M10 and ANVISA (Brazil) guidelines, assessing selectivity, linearity, accuracy, precision, and robustness. The method was applied for the first time to evaluate release, permeation, and retention profiles of a nasal formulation.
Jeniffer Viviana Ramirez Hernández, Laura da Silva Machado, Flávia Nathiely Silveira Fachel, Sara Elis Bianchi, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +6 more
wiley   +1 more source

Hydrogels Under Superchaotropic Control: Polyoxometalate Stabilization and pH‐Responsive Crosslinking in Cellulose Ether Solutions

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Superchaotropic binding of Keggin polyoxometalates (POMs) to non‐ionic biopolymers like cellulose ethers (CEs) stabilizes otherwise hydrolytically unstable POMs in aqueous solution and allows conversion of pH‐nonresponsive polymers into pH‐responsive soft materials. The pH‐driven conversion from plenary to lacunary POMs switches superchaotropic binding
Vighnesh B. Lokare, Amina Ledinic, Nina Wehr, Max Hohenschutz   +3 more
wiley   +2 more sources

Current and Future Issues in the Development of Spinal Agents for the Management of Pain. [PDF]

, 2017
Targeting analgesic drugs for spinal delivery reflects the fact that while the conscious experience of pain is mediated supraspinally, input initiated by high intensity stimuli, tissue injury and/or nerve injury is encoded at the level of the spinal ...
Fisher, Casey J, Hockman, Tyler M, Wiese, Ashley J, Yaksh, Tony L   +3 more
core   +2 more sources

Development of venetoclax with 2-hydroxypropyl-beta-cyclodextrin inclusion complex for improved bioavailability

Journal of Biomolecular Structure and Dynamics
Cyclodextrin complexes loaded with venetoclax for improved solubility and therapeutic efficacy as repurposed drug. The venetoclax-cyclodextrin inclusion complex was prepared using kneading method. Primarily in-silico molecular docking study was performed to examine the possible interaction between venetoclax and hydroxypropyl-β-cyclodextrin (HP-β-CD ...
Smalant Kishor Patil, Padakanti Sandeep Chary, Sarvan Maddipatla, Y.V Madhavi, Siva Singothu, Vasundhra Bhandari, Ekta Pardhi, Kuldeep Kumar Bansal, Neelesh Kumar Mehra   +8 more
openaire   +2 more sources

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

Characterisation of 2-HP-β-cyclodextrin-PLGA nanoparticle complexes for potential use as ocular drug delivery vehicles

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Aim 2-HP-β-cyclodextrin-PLGA nanoparticle complexes were prepared to enhance the aqueous humour delivery of Triamcinolone acetonide.Materials & methods Drug-loaded 2-HP-β-CD/PLGA nanoparticle complexes prepared by adapting a quasi-emulsion solvent ...
Fan Li, Yuqin Wen, Yan Zhang, Kangyu Zheng, Junfeng Ban, Qingchun Xie, Yifeng Wen, Qing Liu, Fohua Chen, Zhenjie Mo, Lizhong Liu, Yanzhong Chen, Zhufen Lu   +12 more
doaj   +1 more source

Guideline for the electrospinning of food biomacromolecules

Food Biomacromolecules, EarlyView.
Abstract Electrospinning, an efficient method for producing micro‐ and nanoscale fibers, has undergone a notable resurgence in recent decades since its origin in the early 20th century, largely driven by advances in nanotechnology. Subsequently, it has been extensively applied across various disciplines, including materials science, biomedicine ...
Manjun Kang, Shengyang Ji, Yucheng Zou
wiley   +1 more source