Results 31 to 40 of about 6,997 (207)

Synthesis of 5-Aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones

open access: yesMolbank, 2023
A two-stage synthesis of 5-aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones (56–66% overall yields) was carried out by refluxing 5-aroyl-3-(benzyloxy)-2-(het)aryl-4H-pyran-4-ones with ammonium acetate in AcOH and subsequent debenzylation.
Elena V. Steparuk   +2 more
doaj   +1 more source

Crystal Chemistry of Zinc Quinaldinate Complexes with Pyridine-Based Ligands

open access: yesCrystals, 2018
Substitution of methanol in [Zn(quin)2(CH3OH)2] (quin− denotes an anionic form of quinoline-2-carboxylic acid, also known as quinaldinic acid) with pyridine (Py) or its substituted derivatives, 3,5-lutidine (3,5-Lut), nicotinamide (Nia), 3 ...
Barbara Modec
doaj   +1 more source

Asymmetric Homogeneous Hydrogenation of 2-Pyridones [PDF]

open access: yesSynlett, 2015
An asymmetric homogeneous hydrogenation of 2(1H)-pyridones has been developed, using a ruthenium complex bearing two chiral N-heterocyclic carbene (NHC) ligands. To the best of our knowledge, the presented reaction is the first example of a homogeneous asymmetric conversion of 2-pyridones into the corresponding enantioenriched 2-piperidones.
Christoph Schlepphorst   +2 more
openaire   +3 more sources

1-[(2-Chloro-7,8-dimethylquinolin-3-yl)methyl]pyridin-2(1H)-one

open access: yesActa Crystallographica Section E, 2010
In the title compound, C17H15ClN2O, the quinoline ring system is nearly planar, with a maximum deviation from the mean plane of 0.074 (2) Å, and makes a dihedral angle of 81.03 (7)° with the pyridone ring ...
F. Nawaz Khan   +3 more
doaj   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

open access: yesAdvanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen   +6 more
wiley   +1 more source

Enantiopure Chiral Crystals: A Powerful Tool for Absolute Asymmetric Synthesis

open access: yesAsian Journal of Organic Chemistry, EarlyView.
This review covers absolute asymmetric syntheses, which allow the preparation of enantiomerically enriched chiral compounds from achiral precursors. By exploiting the crystallization of certain compounds as a conglomerate, enantiopure chiral crystals are spontaneously obtained.
Jiacheng Li, Valérie Alezra
wiley   +1 more source

ChemInform Abstract: PHOTOADDUCTS OF 2‐PYRIDONES WITH CHLOROETHYLENES AND THEIR DERIVATIVES [PDF]

open access: yesChemischer Informationsdienst, 1981
AbstractDie Photoreaktionen werden in Gegenwart eines Sensibilisators (Pyridon, Benzophenon, Xanthon) durchgeführt.
Sanetada Kumamoto   +3 more
openaire   +3 more sources

Anti-Inflammatory and Proangiogenic Metabolites from the Hadal Trench-Derived Fungus Acremonium dichromosporum YP-213

open access: yesMarine Drugs, 2023
Four new compounds, including two ascochlorin-type meroterpenoids acremocholrins A (1) and B (2), one pyridone alkaloid acremopyridone A (7), and one cyclopentenone derivative acremoketene A (12), together with eight known compounds (3–6 and 8–11), were ...
Yan Zhang   +7 more
doaj   +1 more source

ChemInform Abstract: Concise Entries to 4‐Halo‐2‐pyridones and 3‐Bromo‐4‐halo‐2‐pyridones. [PDF]

open access: yesChemInform, 2015
Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di- and (3,4,5-tri)-halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (copper-mediated) halogenation, with a 2-chloro or a 2-benzyl­oxy moiety serving as a masked 2-pyridone.
Gallagher, Timothy, Honraedt, Aurelien
openaire   +5 more sources

Dichlorido[1-(1,10-phenanthrolin-2-yl)-2-pyridone]cadmium(II)

open access: yesActa Crystallographica Section E, 2008
In the title mononuclear complex, [CdCl2(C17H11N3O)], the CdII ion assumes a distorted trigonal–bipyramidal coordination geometry. The pyridone plane is twisted out of the 1,10-phenanthroline mean plane by 43.8 (3)°.
Jin-Min Li
doaj   +1 more source

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