Results 31 to 40 of about 6,930 (204)

Enzymatic synthesis of vitamin B6 precursor [PDF]

open access: yesJournal of the Serbian Chemical Society, 2013
3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Prlainović Nevena Ž.   +4 more
doaj   +1 more source

Ribonucleotide reductase, a novel drug target for gonorrhea

open access: yeseLife, 2022
Antibiotic-resistant Neisseria gonorrhoeae (Ng) are an emerging public health threat due to increasing numbers of multidrug resistant (MDR) organisms. We identified two novel orally active inhibitors, PTC-847 and PTC-672, that exhibit a narrow spectrum ...
Jana Narasimhan   +15 more
doaj   +1 more source

Gas-phase Lifetimes of Nucleobase Analogues by Picosecond Pumpionization and Streak Techniques

open access: yesCHIMIA, 2014
The picosecond (ps) timescale is relevant for the investigation of many molecular dynamical processes such as fluorescence, nonradiative relaxation, intramolecular vibrational relaxation, molecular rotation and intermolecular energy transfer, to
Susan Blaser   +3 more
doaj   +1 more source

rac-2-Methyl-3,4,5,6-tetrahydro-2H-2,6-methano-1,3-benzoxazocin-4-one

open access: yesActa Crystallographica Section E, 2010
The title compound, C12H13NO2, represents a conformationally restricted 2-pyridone analogue of 1,4-dihydropyridine-type calcium antagonists and was selected for a crystal structure determination in order to explore some aspects of drug-receptor ...
Viktor Kettmann   +2 more
doaj   +1 more source

Synthesis, structure and solvatochromic properties of 3-cyano-4,6-diphenyl-5-(3- and 4-substituted phenylazo)-2-pyridones [PDF]

open access: yesJournal of the Serbian Chemical Society, 2010
A series of some new pyridone arylazo dyes was synthesized from the corresponding diazonium salts and 3-cyano-4,6-diphenyl-2-pyridone using the classical reaction for the synthesis of the azo compounds.
NINA TODOROVIĆ   +5 more
doaj  

Supramolecular Potential of Vanadium β-Diketonate and Picolinate Compounds and The First One-dimensional Oxidovanadium(IV) Complex with β-Diketonate Ligand

open access: yesActa Chimica Slovenica, 2014
Three vanadium compounds with β-diketonato or picolinato ligands were prepared and structurally characterized. In compounds [VO(tfpb)2]∞ (1) (tfpb = 4,4,4-trifluoro-1-phenylbutane-1,3-dionate) and [VO(acac)2(2-pyridone)] (2) the coordination of vanadium ...
Tanja Koleša Dobravc   +2 more
doaj   +1 more source

Synthesis of 5-Aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones

open access: yesMolbank, 2023
A two-stage synthesis of 5-aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones (56–66% overall yields) was carried out by refluxing 5-aroyl-3-(benzyloxy)-2-(het)aryl-4H-pyran-4-ones with ammonium acetate in AcOH and subsequent debenzylation.
Elena V. Steparuk   +2 more
doaj   +1 more source

1-[(2-Chloro-7,8-dimethylquinolin-3-yl)methyl]pyridin-2(1H)-one

open access: yesActa Crystallographica Section E, 2010
In the title compound, C17H15ClN2O, the quinoline ring system is nearly planar, with a maximum deviation from the mean plane of 0.074 (2) Å, and makes a dihedral angle of 81.03 (7)° with the pyridone ring ...
F. Nawaz Khan   +3 more
doaj   +1 more source

Asymmetric Homogeneous Hydrogenation of 2-Pyridones [PDF]

open access: yesSynlett, 2015
An asymmetric homogeneous hydrogenation of 2(1H)-pyridones has been developed, using a ruthenium complex bearing two chiral N-heterocyclic carbene (NHC) ligands. To the best of our knowledge, the presented reaction is the first example of a homogeneous asymmetric conversion of 2-pyridones into the corresponding enantioenriched 2-piperidones.
Christoph Schlepphorst   +2 more
openaire   +3 more sources

Crystal Chemistry of Zinc Quinaldinate Complexes with Pyridine-Based Ligands

open access: yesCrystals, 2018
Substitution of methanol in [Zn(quin)2(CH3OH)2] (quin− denotes an anionic form of quinoline-2-carboxylic acid, also known as quinaldinic acid) with pyridine (Py) or its substituted derivatives, 3,5-lutidine (3,5-Lut), nicotinamide (Nia), 3 ...
Barbara Modec
doaj   +1 more source

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