Results 71 to 80 of about 10,839 (246)

catena-Poly[[(nitrato-κ2O,O′)silver(I)]-μ3-4-pyridone-κ3O:O:O]

open access: yesActa Crystallographica Section E, 2009
In the title complex, [Ag(NO3)(C5H5NO)]n, the AgI atom is coordinated by two O atoms from two different 4-pyridone ligands and two O atoms from one nitrate anion, displaying a nearly planar coordination geometry.
Xian-Ge Wu, Jun-Xia Xiao, Liang Qin
doaj   +1 more source

Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]

open access: yes, 2018
Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael   +8 more
core   +3 more sources

Shedding Light on the Precatalytic Mixture of Pd(OAc)2 and Cooperating Bipyridone Ligands for the C─H Functionalization of Arenes

open access: yesChemCatChem, Volume 18, Issue 1, 15 January 2026.
The reactions of the common palladium precursors Pd(OAc)2 and PdCl2 and cooperating bipyridone ligands leads to well defined complexes which are general precatalysts for the direct C─H arylation of arenes, more active than Pd(OAc)2/ligand mixtures in nonpolar solvents.
Francisco Villalba   +2 more
wiley   +1 more source

Synthesis of Some New Enaminoketones, Analogous of Milrinone, 4,Pyrones and Related 4-Pyridones [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 1996
Synthesis of 4-(N,N- dimethylamino)-3-aryl-3-butene-2-one, ethyl-5-aryl-4-oxo-4H-pyran-2-carboxylate, ethyl-5-aryl-4-pyridones-2-carboxylate and 5-aryl-3-cyano-5-methyl-2-pyridones (aryl=3-thienyl, 2-furyl) are described.
Aziz Shahrisa, Salar Hemmati
doaj  

Design, Synthesis and Anti-fibrosis Activity Study of N1-Substituted Phenylhydroquinolinone Derivatives

open access: yesMolecules, 2012
Pirfenidone (5-methyl-1-phenyl-2(1H)-pyridone, PFD) is a small-molecule compound acting on multiple targets involved in pathological fibrogenesis and is effective to increase the survival of patients with fibrosis, such as idiopathic pulmonary fibrosis ...
Jun Chen   +5 more
doaj   +1 more source

Tetrapodal amidoxime ligands I. Coordination isomerism due to self-complementary dimerization of a pyramidal cobalt(III) coordination module [PDF]

open access: yes, 2012
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Boyd, John P.   +2 more
core   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao   +7 more
wiley   +1 more source

Perchloratobis[1-(1,10-phenanthrolin-2-yl)-2-pyridone]zinc(II) perchlorate

open access: yesActa Crystallographica Section E, 2009
In the title mononuclear complex, [Zn(ClO4)(C17H11N3O)2]ClO4, the ZnII ion is coordinated in a distorted octahedral geometry. The dihedral angles between the pyridine rings and the mean planes of the 1,10-phenanthroline ring system in each of the 1-(1,10-
Qing Ru Zhao, Qi Sheng Liu, Qing Yun Liu
doaj   +1 more source

Metabolic Profiling of the EmDia Cohort by LC‐MS Reveals Empagliflozin‐Intake Associated Regulation of 1,5‐anhydroglucitol and Urate

open access: yesPROTEOMICS, Volume 26, Issue 1, Page 44-56, January 2026.
ABSTRACT The EmDia trial, designed to study the effects of the sodium glucose cotransporter‐2 (SGLT2) inhibitor empagliflozin on cardiovascular comorbidities in type 2 diabetes mellitus (T2DM) patients, has been investigated for short‐term metabolic alterations by a limited set of clinical assays. To expand on this data, we report on the development of
Fabian Schmitt   +7 more
wiley   +1 more source

Tautomeric Equilibria Studies by Mass Spectrometry [PDF]

open access: yes, 2008
Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro   +3 more
core   +1 more source

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