Results 11 to 20 of about 24,424,699 (186)
Reaction of a 3-aryilidene-2-thiohydantoin derivative with polymeric trans-[CuCl2(DMSO)2]n complex: Unexpected isomerization to dinuclear cis-[{CuCl(DMSO)2}(μ-Cl)]2 [PDF]
Journal of the Serbian Chemical Society, 2020 The 3-arylidene-2-thiohydantoin derivative, 3-[(2-hydroxybenzylidene) amino]-2-thioxoimidazolidin-4-one, was synthesized in a two-step condensation reaction of 2-hydroxybenzaldehyde, thiosemicarbazide and ethyl chloroacetate.
Stanić Petar B. +6 more
doaj +4 more sources
1-Acetyl-2-thiohydantoin [PDF]
Acta Crystallographica Section C Crystal Structure Communications, 1998 In the title compound (1-acetyl-4-oxoimidazolidine-2-thione, C5H6N2O2S), the plane of the acetyl group forms an angle of 6.7° with the essentially planar thiohydantoin ring. N—H⋯O hydrogen bonds create quasiplanar chains of molecules along the y axis.
J. S. Casas +5 more
core +5 more sources
Synthesis and Identification of Heterobivalent Anticancer Compounds Containing Urea and 5-Arylidene-2-Thiohydantoin Motifs. [PDF]
ChemistrySelectA synthetic approach to the synthesis of novel heterobivalent compounds containing urea and 5‐arylthiohydantoin groups was developed for the preparation of a mixture‐based library. Through the screening and deconvolution of the library, six hits with βC branched residues at R1 and imidazyl residue at R3 were identified exhibiting moderate inhibitory ...
Whitely C, Winburn H, Li Y.
europepmc +2 more sources
A Plausible Prebiotic One-Pot Synthesis of Orotate and Pyruvate Suggestive of Common Protometabolic Pathways. [PDF]
Angew Chem Int Ed Engl, 2022 A prebiotic synthesis of the nucleobase orotate, and the citric acid cycle intermediate pyruvate, proceeds in a single pot from two small glycine derivatives, hydantoin and glyoxylate, under mild aqueous conditions. These findings support a co‐evolution of pathways to core protometabolites and nucleic acid building blocks in a common environment ...
Clay AP +5 more
europepmc +3 more sources
SYNTHESES, ANTIMICROBIAL ACTIVITY AND MASS SPECTRAl INVESTIGATION OF SOME NEW THIOHYDANTOIN AND THIAZOLE DERIVATIVES. [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2012 5-(p-Tolyl)-2-[(p-tolylethylidene)hydrazino] thiazole (3) and 3-[(p-tolylethylidene )amino]-2-thiohydantoin (6) have been prepared via cyclization of p-methyl acetophenone thiosemicarbazone (2) with p-methylphenacyl bromide and ethyl chloroacetate ...
haba Abd El Hady
doaj +1 more source
Aldol Reactions of Conformationally Stable Axially Chiral Thiohydantoin Derivatives. [PDF]
ACS Omega, 2021 Two novel axially chiral ortho-trifluoromethylphenyl thiohydantoin derivatives have been prepared atroposelectively from the reaction of R and S alanine methyl ester HCl salts with ortho-trifluoromethylphenyl isothiocyanate in the presence of triethyl ...
Sarigul Ozbek S, Bacak Erdik M, Dogan I.
europepmc +3 more sources
Synthesis of potent antileukemic quinazoline-thiohydantoin fused heterocycles enabled by metal-free domino reaction [PDF]
, 2023 Heterocyclic compounds play a central role in drug development research and are contained in most pharmaceuticals on the market. Quinazoline and thiohydantoin are heterocycles and hold very prominent positions due to their diverse pharmacological ...
Svetlana B., Tsogoeva +11 more
core +2 more sources
HYDANTOINS: THE SYNTHESIS OF 2-THIOHYDANTOIN. [SEVENTH PAPER.] [PDF]
Journal of the American Chemical Society, 1911 n ...
Johnson, Treat B., Nicolet, Ben H.
openaire +1 more source
Acta Chimica Slovenica, 2020 The present work is directed toward preparation and structural characterization of two novel Cu(I) arylsulfonate π-complexes with 3-allyl-2-thiohydantoin, namely [Cu2(Hath)4](C6H5SO3)2 (1) and [Cu2(Hath)4](p-CH3C6H4SO3)2·2H2O (2) (Hath = 3-allyl-2 ...
Andrii Fedorchuk +3 more
doaj +1 more source
The Chemical Record, Volume 23, Issue 11, November 2023., 2023 Efforst are described for developing Brønsted base‐catalyzed, site‐ and stereoselective α‐functionalization of a variety of unsaturated enolizable carbonyl compounds via transient enolates featuring an extended π‐system. Abstract Chiral Brønsted base (BB) catalyzed asymmetric transformations constitute an important tool for synthesis.
Mikel Oiarbide, Claudio Palomo
wiley +1 more source