Results 21 to 30 of about 848 (152)

Kinetic investigation of reactions of a 3-arylidene-2-thiohydantoin derivative with palladium (II) salts [PDF]

Journal of the Serbian Chemical Society
1H-NMR spectroscopy was used to monitor the reactions of an arylidene 2-thiohydantoin derivative, 3-((phenylmethylene)amino)-2-thioxo-4-imidazolidinone (3), with PdCl2, cis-[PdCl2(dmso-S)2] and K2[PdCl4] in DMSO-d6 in order to elucidate the reaction ...
Stanić Petar B., Ašanin Darko P., Soldatović Tanja V., Živković Marija D.   +3 more
doaj   +1 more source

Synthesis and Fluorescence Mechanism of the Aminoimidazolone Analogues of the Green Fluorescent Protein: Towards Advanced Dyes with Enhanced Stokes Shift, Quantum Yield and Two‐Photon Absorption

European Journal of Organic Chemistry, Volume 2021, Issue 41, Page 5649-5660, November 8, 2021., 2021
Intramolecularly hydrogen‐bonded analogues of the green fluorescence protein chromophore with an aminoimidazole moiety were synthesised and characterised. The fluorescence mechanism and substituent effects were investigated in a combined experimental‐computational approach, and a 279‐fold improvement in the quantum yield was realised.
Ervin Kovács, Levente Cseri, Attila Jancsó, Ferenc Terényi, Anna Fülöp, Balázs Rózsa, Gábor Galbács, Zoltán Mucsi   +7 more
wiley   +1 more source

HYDANTOINS: THE SYNTHESIS OF 2-THIOHYDANTOIN. [SEVENTH PAPER.] [PDF]

Journal of the American Chemical Society, 1911
n ...
Johnson, Treat B., Nicolet, Ben H.
openaire   +1 more source

Synthesis and Biological Evaluation of Dantrolene‐Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases

ChemMedChem, Volume 16, Issue 18, Page 2807-2816, September 16, 2021., 2021
Simpler is better: Structural modifications of the chemical structure of dantrolene, previously disclosed as a repositionable drug with potential for Alzheimer's disease, allowed preparing new small molecules with multitarget activity profile. Compared to dantrolene, molecular simplification resulted in less toxic and more soluble compounds.
Isabella Bolognino, Nicola Giangregorio, Annamaria Tonazzi, Antón L. Martínez, Cosimo D. Altomare, María I. Loza, Sara Sablone, Saverio Cellamare, Marco Catto   +8 more
wiley   +1 more source

1-Acetyl-2-thiohydantoin

Acta Crystallographica Section C Crystal Structure Communications, 1998
In the title compound (1-acetyl-4-oxoimidazolidine-2-thione, C5H6N2O2S), the plane of the acetyl group forms an angle of 6.7° with the essentially planar thiohydantoin ring. N—H⋯O hydrogen bonds create quasiplanar chains of molecules along the y axis.
J. S. Casas, A. Castiñeiras, D. Couce, N. Playá, J. Sordo, J. M. Varela   +5 more
openaire   +3 more sources

New platinum(II) complexes of cycloalkanespiro-5-(2-thiohydantoins). Synthesis and quantum chemical investigation

Acta Chimica Slovenica, 2015
Synthesis and characterization of new Pt(II) complexes of cyclohexanespiro-5-(2-thiohydantoin)  (L1) and cycloheptanespiro-5-(2-thiohydantoin) (L2) are discussed. The new complexes are studied by elemental analysis, IR, ATR FTIR spectroscopy.
Petja E. Marinova, Marin Marinov, Vassil Delchev, Neyko Stoyanov   +3 more
doaj   +1 more source

Reactions with 2-Thiohydantoin, Synthesis of Imidazothiazolone Derivatives and Mannich Bases of 5-Arylidene-2-thiohydantoin

Zeitschrift für Naturforschung B, 1976
Treatment of 5-arylidene-2-thiohydantoin (1a-d) with alkyl bromoacetate and chloroacetic acid gave the esters 2a-f and the acids 2g-j, respectively. 2a was refluxed with concentrated hydrochloric acid to give 5-benzylidene hydantoin. 2 was cyclized with acetic anhydride to give the bicyclic product 3. 5-Arylidene-2-thiohydantoin derivatives (1a, b) and
A. F. A. Shalaby, H. A. Daboun, M. A. Abdel Aziz   +2 more
openaire   +2 more sources

HYDANTOINS: THE HISTORY OF 2-THIOHYDANTOIN. XXII. [PDF]

Journal of the American Chemical Society, 1913
n ...
openaire   +2 more sources

Synthesis and Biological Evaluation of Novel Dispiro-Indolinones with Anticancer Activity

Molecules, 2023
Novel variously substituted thiohydantoin-based dispiro-indolinones were prepared using a regio- and diastereoselective synthetic route from 5-arylidene-2-thiohydantoins, isatines, and sarcosine.
Yan A. Ivanenkov, Maxim E. Kukushkin, Anastasia A. Beloglazkina, Radik R. Shafikov, Alexander A. Barashkin, Andrey A. Ayginin, Marina S. Serebryakova, Alexander G. Majouga, Dmitry A. Skvortsov, Viktor A. Tafeenko, Elena K. Beloglazkina   +10 more
doaj   +1 more source

Reactivity of 2-Thiohydantoins Towards Various Electrophilic Reagents: Applications to the Synthesis of New 2-Ylidene-3,5-dihydro-4H-imidazol-4-ones.

Molecules, 2004
A new route to 5-(imidazolidin-2-ylidene)-2-methylsulfanyl-3,5-dihydro-imidazol-4-ones 4a-c using ketene dithioacetal intermediates 3a-c is described.
Jean Pierre Bazureau, François Carreaux, Jean-René Chérouvrier   +2 more
doaj   +1 more source