Synthesis and Biological Evaluation of Novel Dispiro-Indolinones with Anticancer Activity
Molecules, 2023 Novel variously substituted thiohydantoin-based dispiro-indolinones were prepared using a regio- and diastereoselective synthetic route from 5-arylidene-2-thiohydantoins, isatines, and sarcosine.
Yan A. Ivanenkov +10 more
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Synthesis and structural characterization of 6-(N-Methyl-pyridin-2-ylcarbamoyl)-pyridine-2-carboxylic acid methyl ester isomers [PDF]
, 2017 A series of monoamide isomers have been successfully synthesised and characterised using combination of common spectroscopic techniques such Fourier Transform Infrared (FT-IR), 1H and 13C Nuclear Magnetic Resonance (NMR) and Ultraviolet-visible (UV-vis).
Maisara Abdul Kadir, +2 more
core +1 more source
Electrochemical investigation of 2-thiohydantoin derivatives as corrosion inhibitors for mild steel in acidic medium [PDF]
, 2021 Four 2-thiohydantoin derivatives were synthesized and their corrosion inhibition properties on mild steel (MS) in 0.5M HCl solution was evaluated using usual gravimetric and electrochemical methods (weight loss, potentiodynamic polarization ...
Cvetković, Vesna S. +5 more
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Normal and Reversed Phases Thin-Layer Chromatography of Arylidene 2- Thiohydantoin Derivatives [PDF]
, 2023 In this paper, the retention behavior of thirteen newly synthesized arylidene derivatives of 2-hydamthione was investigated by normal and reversed phases thin-layer chromatography.
Ačanski, Marijana +6 more
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Chemical Reactivity of 2-Thiohydantoin Derivatives
Zeitschrift für Naturforschung B, 1977 Treatment of 5-arylazo-2-thiohydantoins (2 a-c) with formaldehyde and the appropriate amine in ethyl alcohol led to the formation of the corresponding Mannich bases 3a-i. 2 a-c reacted with methyl bromoacetate and/or chloroacetic acid to give the esters 5 a-c and/or the free acids 5d-f, respectively. 5e also obtained by treating 5 b with aqueous sodium
A. F. A. Shalaby +2 more
openaire +1 more source
Molecules, 2004 A new route to 5-(imidazolidin-2-ylidene)-2-methylsulfanyl-3,5-dihydro-imidazol-4-ones 4a-c using ketene dithioacetal intermediates 3a-c is described.
Jean Pierre Bazureau +2 more
doaj +1 more source
Solvent effects on the structure-property relationship of anticonvulsant hydantoin derivatives: A solvatochromic analysis [PDF]
, 2011 Considering the pharmaceutical importance of hydantoins, a set of 25 derivatives of phenytoin, nirvanol and 5-methyl-5-phenylhydantoin, the lipophilicities of which were gradually increased by the introduction of different alkyl, cycloalkyl and alkenyl ...
Gordana Ušćumlić +2 more
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Synthesis and crystal structure of (S)-5-isopropyl-5-methyl-2-thiohydantoin [PDF]
, 2013 (S)-5-Isopropyl-5-methyl-2-thiohydantoin was synthesized by one-pot reaction of α-methyl-L-valine and thiourea in the absence of solvent. The crystal structure of this compound has been determined from single crystal X-ray diffraction data.
Fujinami, Shuhei +8 more
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Антикорозиона активност деривата шифових база 2-тиохидантоина за меки челик у 0,5 m hcl [PDF]
, 2022 Several 2-thiohydаntоin–Shiff base derivatives were prepared as ecofriendly corrosion inhibitors for mild steel in acid environment. Their anticorrosion properties were studied on mild steel in 0.5 M HCl solution as corrosion electrolyte by using ...
Cvetković, Vesna S. +6 more
core +2 more sources
Molecules, 2011 2-(Alkyl-1-yl)-1H-imidazol-5(4H)-ones 5a–n were synthesized via nucleophilic substitution of the methylsulfanyl group of the corresponding 2-(methylthio)-1H-imidazol-5(4H)-ones 3a–c with suitably substituted secondary amines.
Edward R. Biehl +2 more
doaj +1 more source