Results 61 to 70 of about 24,424,699 (186)
Chiral Quaternary Ammonium Salt‐Catalyzed Enantioselective Addition Reactions of Hydantoins
Helvetica Chimica Acta, Volume 107, Issue 3, March 2024.Abstract We herein report a protocol for the asymmetric 1,4‐addition of hydantoins to various Michael acceptors by utilizing Cinchona alkaloid‐based chiral quaternary ammonium salt catalysts. Various products were obtained with moderate to good enantioselectivities and accompanying computational investigations helped to identify key interactions ...
Katharina Röser +5 more
wiley +1 more source
Experimental and computational study of the energetics of hydantoin and 2-thiohydantoin [PDF]
, 2013 This work reports an experimental and a theoretical study of two imidazolidine derivatives, hydantoin (CAS No. 461-72-3) and 2-thiohydantoin (CAS No. 503-87-7).
Ana L R Silva +5 more
core +1 more source
Dopaminergic neuronal death via necroptosis in Parkinson's disease: A review of the literature
European Journal of Neuroscience, Volume 59, Issue 6, Page 1079-1098, March 2024.We reviewed the current literature on the potential role of necroptosis, a recently characterized regulated cell death mechanism, in Parkinson's disease (PD) pathogenesis. We summarized findings from studies on necroptosis in PD preclinical models and PD human tissue samples, discussing how manipulating necroptosis might open a novel therapeutic ...
Maria Regoni +2 more
wiley +1 more source
Synthesis and molecular modeling studies of new thiohydantoin-triazole hybrids as anticancer agents
Journal of Saudi Chemical SocietyThe targeted thiohydantoin-triazole hybrid compounds 5a-d and 9a-d were synthesized by the copper-catalyzed click reaction of 2-azido-N-arylacetamides 3a-d with the appropriate alkynes, thiohydantoin moiety linked to a propargyl group.
Wael M. Alamoudi
doaj +1 more source
Journal of Biomedical Materials Research Part A, Volume 112, Issue 2, Page 288-295, February 2024.Abstract Immunoisolation of pancreatic islets in alginate microcapsules allows for transplantation in the absence of immunosuppression but graft survival time is still limited. This limited graft survival is caused by a combination of tissue responses to the encapsulating biomaterial and islets. A significant loss of islet cells occurs in the immediate
Alexandra M. Smink +4 more
wiley +1 more source
Food Science &Nutrition, Volume 12, Issue 1, Page 471-480, January 2024.The exposure systems of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts diHOPrVal were compared. DiHOPrVal formation was observed using several chemicals other than glycidol with different behaviors in vitro and in vivo. However, in both cases, the amount of diHOPrVal produced was very small compared with glycidol. This study
Yuko Shimamura +4 more
wiley +1 more source
Synthese von 6-Thioxo-1,2,5-oxadiazinan-3-onen und Umwandlung in 3-Amino-2-thiohydantoine und 3-Hydroxy-2-thiohydantoine / Synthesis of 6-Thioxo-1,2,5-oxadiazinan-3-ones and Transformation into 3-Amino-2-thiohydantoins and 3-Hydroxy-2-thiohydantoins [PDF]
Zeitschrift für Naturforschung B, 2006 6-Thioxo-1,2,5-oxadiazinan-3-ones 5, easily available by cyclic thiocarbonylation of Nα ,Ndisubstituted α-aminocarbohydroxamic acids 4 with 1,1′-thiocarbonyldiimidazole, are transformed by hydrazine or hydroxylamine into 3-amino-2-thiohydantoins 6 and 3-hydroxy-2-thiohydantoins 7.
Detlef Geffken, Alf Ploetz
openaire +1 more source
InorganicsThis study presents a thorough investigation of chemical outcomes during the reaction of cisplatin and 2-thiohydantoin ligands in the presence of DMSO. Aided by NMR spectroscopy and quantum chemical calculations, the influence of DMSO substitution on the
Petar B. Stanić +6 more
doaj +1 more source
Apoptotic Effects of Some Thiohydantoin Derivatives
, 2010 WOS: 000282700000017Objectives: The aim of this study is to investigate the effects of newly synthesized 3-phenly-and 3-(4-methoxyphenyl)-2-thiohydantoin derivatives on 5RP7 ve CO25 cell apoptosis.
Akalın Çiftçi, Gülsen +1 more
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