Results 161 to 170 of about 9,716 (212)

The Link Between Oxysterols and Gut Microbiota in the Co-Dysfunction of Cognition and Muscle. [PDF]

Nutrients
Ju M, Feng W, Guo Z, Yang K, Wang T, Yu H, Qi C, Liu M, Tao J, Xiao R.   +9 more
europepmc   +1 more source

Deletion of CH25H and LIPA Genes in Human Abolishes Biosynthesis of 25-Hydroxycholesterol but not of 7α,25-Dihydroxysterols and Enhances Non-enzymatic Cholesterol Oxidation: Metabolic Changes are Partially Reversed by Hematopoietic Stem Cell Transplant^‡

Yutuc E, Ghosh A, Abdel-Khalik J, Goenka A, Asgari MA, Lopez-Castejon G, Beaman GM, Wynn RF, Newman WG, Jones SA, Griffiths WJ, Wang Y.   +11 more
europepmc   +1 more source

Brain cholesterol metabolites cause significant neurodegeneration in human iPSC-derived neurons

Feng Y, Mazumder B, Konno T, Hui E, Brockhoff M, Davi V, Lu M, Ward E, Stephens A, Dai W, Fernandez-Villegas A, Fusco G, Ali Asgari M, Avezov E, De Simone A, Wang Y, Griffiths WJ, Kaminski C, Kaminski Schierle G.   +18 more
europepmc   +1 more source

(24S)-Hydroxycholesterol efflux from neuronal cells by ABC proteins

(24S)-Hydroxycholesterol efflux from neuronal cells by ABC proteins
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Cholesterol metabolism and glaucoma: Modulation of Muller cell membrane organization by 24S-hydroxycholesterol

Chemistry and Physics of Lipids, 2017
Glaucoma is a progressive and irreversible blinding neuropathy that is characterized by the loss of retinal ganglion cells (RGCs). Muller Glial Cell (MGC) activation is induced in retinal gliosis. MGCs are the most numerous glial cells in the retina and one of their roles is to sustain cholesterol homeostasis. 24S-hydroxycholesterol (24S-OHC) is one of
Pierre Henry Gabrielle, Catherine Creuzot-Garcher, Alain Bron   +2 more
exaly   +5 more sources

Accumulation of 24S-hydroxycholesterol in neuronal SK-N-BE cells treated with hexacosanoic acid (C26:0): Argument in favor of 24S-hydroxycholesterol as a potential biomarker of neurolipotoxicity

Revue Neurologique, 2015
Cholesterol oxide derivatives (oxysterols) are viewed as potential biomarkers of neurodegenerative diseases. 24S-hydroxycholesterol, an oxysterol produced only in brain neurons, is often found for unknown reasons in increased levels in the plasma in patients with neurodegenerative diseases. On human neuronal SK-N-BE cells treated with hexacosanoic acid
Gérard Lizard
exaly   +4 more sources

24S-hydroxycholesterol affects redox homeostasis in human glial U-87 MG cells.

Molecular and Cellular Endocrinology, 2019
The cholesterol metabolite 24(S)-hydroxycholesterol (24S-OHC) allows cholesterol excretion from the brain and was suggested to be critically involved in physiological as well as neurodegenerative processes.
L. Cigliano, M. Spagnuolo, G. Napolitano, Lucia Iannotta, G. Fasciolo, D. Barone, P. Venditti   +6 more
semanticscholar   +7 more sources

24S-Hydroxycholesterol and Cerebellar Degeneration: Insights from SCA2

The Cerebellum, 2022
Sara Locci, Valentina Nidiaci, N. De Stefano, Valerio Leoni, A. Mignarri   +4 more
semanticscholar   +3 more sources