Results 11 to 20 of about 246,364 (197)
Viruses, 2023 Marek’s disease virus (MDV) causes a deadly lymphoproliferative disease in chickens, resulting in huge economic losses in the poultry industry. It has been suggested that MDV suppresses the induction of type I interferons and thus escapes immune control.
Nitin Kamble +6 more
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Molecular Metabolism, 2020 Objective: Expansion of visceral adipose tissue (VAT) and metabolic inflammation are consequences of obesity and associated with type 2 diabetes (T2DM).
Lucia Russo +7 more
doaj +1 more source
Regulating Innate and Adaptive Immunity for Controlling SIV Infection by 25-Hydroxycholesterol
Frontiers in Immunology, 2018 Persistent inflammation and extensive immune activation have been associated with HIV-1/SIV pathogenesis. Previously, we reported that cholesterol-25-hydroxylase (CH25H) and its metabolite 25-hydroxycholesterol (25-HC) had a broad antiviral activity in ...
Tongjin Wu +14 more
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24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation. [PDF]
PLoS ONE, 2017 N-methyl-D-aspartate receptors (NMDARs), a major subtype of glutamate receptor mediating excitatory transmission throughout the CNS, participate in ischemia-induced neuronal death.
Min-Yu Sun +3 more
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Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2021 Houttuynia cordata Thunb. (HC) is a traditional medicinal plant with a variety of pharmaceutical activities. The objective of this study was to investigate the growth, photosynthetic parameters, and antioxidant properties of HC plants in response to ...
Yu-Syuan LI +3 more
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The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus
Viruses, 2019 Cholesterol, an essential component of mammalian cells, is also an important factor in the replicative-cycles of several human and animal viruses.
Ghada T. Shawli +3 more
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A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol
Journal of Lipid Research, 2015 Cholesterol homeostasis is regulated not only by cholesterol, but also by oxygenated cholesterol species, referred to as oxysterols. Side-chain oxysterols, such as 25-hydroxycholesterol (25-HC), regulate cholesterol homeostasis through feedback ...
David B. Iaea +10 more
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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner
Journal of Neuroinflammation, 2020 Background Genome-wide association studies of Alzheimer’s disease (AD) have implicated pathways related to lipid homeostasis and innate immunity in AD pathophysiology.
Man Ying Wong +13 more
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Respiratory Research, 2012 Background 25-hydroxycholesterol (25-HC) is one of the oxysterols, which are oxidized derivatives of cholesterol, and has been reported to be involved in the pathogenesis of atherosclerosis and Alzheimer’s disease. In lung, the possible involvement of 25-
Koarai Akira +11 more
doaj +1 more source
Frontiers in Endocrinology, 2021 ObjectiveThe use of once-daily dual-release HC (DR-HC) in primary adrenal insufficiency (PAI) is often associated with benefits in metabolic parameters when compared to immediate-release HC (IR-HC).
Francesca Delle Cese +6 more
doaj +1 more source