Results 221 to 230 of about 136,200 (251)
ABSTRACT Rainbow trout (Oncorhynchus mykiss) exhibit extensive genomic diversity shaped by domestication, life history and geographic origin. To advance the development of a comprehensive pangenome reference, we present new de novo genome assemblies of two genetically and ecologically distinct lines: Whale Rock (WR; wild, landlocked, Central California)
Ali Ali +9 more
wiley +1 more source
Cucumber green mottle mosaic virus: A persistent seed‐borne threat to cucurbits
Cucumber green mottle mosaic virus (CGMMV) is a highly stable, seed‐borne tobamovirus that threatens global cucurbit production. Its efficient mechanical and seed transmission, long‐term environmental persistence, and the spread of Clade II CGMMV isolates drive its rapid dissemination and cause severe yield losses.
Esperanza Gea‐Caballero +1 more
wiley +1 more source
Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias +7 more
wiley +1 more source
This integrated high‐resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34‐mutant expands the spectrum of associated genetic changes and underscores the presence of universal TP53 abnormalities at copy number, sequence, and protein expression level, with frequent yet largely unrecognized TP53 copy‐neutral loss of ...
Jorge A. Trejo‐Lopez +28 more
wiley +1 more source
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña +20 more
wiley +1 more source
ABSTRACT The rapid expansion of multilingual digital platforms has made the accurate analysis of user‐generated content across different languages and cultural contexts increasingly essential. However, existing methods struggle to maintain consistent performance due to linguistic diversity, morphological complexity, and structural variations in text ...
Abdulkadir Şeker
wiley +1 more source
Alternative Polyadenylation Dynamics During the Rice Blast Immune Response
In rice, infection by the blast fungus Magnaporthe oryzae triggers genome‐wide alternative polyadenylation (APA) dynamics, leading to widespread 3′ UTR shortening in stress‐responsive transcripts. This shortening enables immunity‐related genes to evade miRNA‐mediated suppression.
Dewei Yang +5 more
wiley +1 more source
Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska +2 more
wiley +1 more source

