Results 231 to 240 of about 136,200 (251)

Dynamic Landscapes of Long Noncoding RNAs During Early Root Development and Differentiation in Glycine max and Glycine soja

Plant, Cell &Environment, Volume 49, Issue 7, Page 3612-3625, July 2026.
ABSTRACT Soybean (Glycine max) is an important crop for its nutritional value. Its wild relative, Glycine soja, provides a valuable genetic resource for improving soybean productivity. Root development and differentiation are essential for soybean plants to take up water and nutrients, store energy and anchor themselves.
Qiaoxia Liang, Hafiz M. Rehman, Jizhou Zhang, Hon‐Ming Lam, Ting‐Fung Chan   +4 more
wiley   +1 more source

Regulation by 3′-Untranslated Regions

Annual Review of Genetics, 2017
3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside an increased generation of alternative 3′-UTR isoforms. In contrast, the number of coding genes, as well as coding region length, has remained similar. This suggests an important role for 3′
Christine Mayr
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Characterization and evolution of 5′ and 3′ untranslated regions in eukaryotes

Gene, 2012
Untranslated regions (UTRs) in eukaryotes play a significant role in the regulation of translation and mRNA half-life, as well as interacting with specific RNA-binding proteins. However, UTRs receive less attention than more crucial elements such as genes, and the basic structural and evolutionary characteristics of UTRs of different species, and the ...
Liu, Honglei, Yin, Jiaming, Xiao, Meili, Gao, Caihua, Mason, Annaliese S., Zhao, Zunkang, Liu, Yingchun, Li, Jiana, Fu, Donghui   +8 more
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The emerging roles of 3′ untranslated regions in cancer

Cancer Letters, 2013
Accumulating evidence suggests that 3' untranlated regions (3' UTRs) are critical for spatial and temporal gene expression in both physiological and pathological conditions. The reprogramming of 3' UTRs by various means is a common phenomenon in cancer; disturbances of 3' UTRs significantly increase the risk of cancer susceptibility by acting both in ...
Jun, Li, Xin, Lu
openaire   +2 more sources

The 3′ Untranslated Region of Prohibitin and Cellular Immortalization

Experimental Cell Research, 1996
We have been studying the role of the evolutionarily conserved prohibitin gene in cellular immortalization and tumor suppression. Immortalized human cells are classified into four complementation groups (A, B, C, and D) based on the ability of fusion hybrids to become senescent.
E R, Jupe, X T, Liu, J L, Kiehlbauch, J K, McClung, R T, Dell'Orco   +4 more
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Characterization of 3′untranslated region (3′UTR) of the MICB gene

Human Immunology, 2013
In this study, the 3'untranslated region (3'UTR) of MHC class I chain-related gene B (MICB) were investigated in 104 healthy, unrelated Han individuals recruited from northern China, using PCR-sequencing method. Seven polymorphic sites were detected including a 2-bp deletion/insertion, a 6-bp deletion/insertion and 5 SNPs. Seven different 3'UTR alleles
FengHua, Pan, XueXiang, Liu, JuFang, Huang, Wei, Tian   +3 more
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Immortalization of Rat Embryo Fibroblasts by a 3′-Untranslated Region

Experimental Cell Research, 1998
We have exploited a cross-species expression screen to search for cellular immortalizing activities. A newt blastemal cDNA expression library was transfected into rat embryo fibroblasts and immortal cell lines were selected. This identified a 1-kb cDNA fragment which has a low representation in the cDNA library and is derived from the 3'-UTR of an ...
A J, Powell, P B, Gates, D, Wylie, C P, Velloso, J P, Brockes, P S, Jat   +5 more
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Tethered function assays using 3′ untranslated regions

Methods, 2002
Proteins that regulate mRNA metabolism are often bipartite: an RNA binding activity confers substrate specificity, and a "functional" domain elicits the biological outcome. In some cases, these two activities reside on different polypeptides that form a complex on the mRNA.
Jeffery, Coller, Marvin, Wickens
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Dehydrogenase Binding to the 3′-Untranslated Region of GLUT1 mRNA

Biochemical and Biophysical Research Communications, 1996
Employing RNA gel mobility shift assays we detected specific binding events between several dehydrogenases and various regions of the GLUT1 mRNA 3'-untranslated region. In particular, the enzymes glyceraldehyde 3-phosphate dehydrogenase (G3PDH), lactate dehydrogenase (LDH), and glucose 6-phosphate dehydrogenase (G6PDH) bound to the GLUT1 3'-UTR while ...
K, McGowan, P H, Pekala
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Conservation of the 3′-untranslated regions of calmodulin mRNAs in cetaceans

Molecular Biology Reports, 2003
Three separate calmodulin (CaM) genes (I, II and III) encoding an identical CaM protein but differing in the 5'- and 3'-untranslated regions of each of the three mRNAs are present and highly conserved in all mammals (so far examined). Primers complementary to the 3'- untranslated region (3'UTR) of each of the three mRNAs occurring in human, rat and ...
F, Friedberg, A A, Saunders, A R, Rhoads
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