Regulation of hBD-2, hBD-3, hCAP18/LL37, and Proinflammatory Cytokine Secretion by Human Milk Oligosaccharides in an Organotypic Oral Mucosal Model [PDF]
Pathogens, 2021 Human milk oligosaccharides (HMOs), the third largest solid fraction in human milk, can modulate inflammation through Toll-like receptor signaling, but little is known about their immunomodulatory potential in the oral cavity.
Ulvi K. Gürsoy +5 more
doaj +3 more sources
Safety of 2′‐fucosyllactose (2’‐FL) produced by a derivative strain (APC199) of Corynebacterium glutamicum ATCC 13032 as a novel food pursuant to Regulation (EU) 2015/2283 [PDF]
EFSA Journal, 2022 Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 2′‐fucosyllactose (2’‐FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) +27 more
doaj +4 more sources
The synergies effect of 3′-sialyllactose and 2′-fucosyllactose on the attenuation of food allergy symptoms in a mouse model [PDF]
Food Science of Animal ProductsThe functional components known as milk oligosaccharides are crucial in the milk of diverse animals. Increasing evidence of immunomodulatory effects of milk oligosaccharides suggests that they may have some therapeutic potential in allergy.
Lina Zhang +4 more
doaj +2 more sources
2'-Fucosyllactose and 3-Fucosyllactose Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Modulating the Intestinal Microbiome. [PDF]
Nutrients, 2023 Ulcerative colitis is an inflammatory bowel disease (IBD) with relapsing and remitting patterns, and it is caused by varied factors, such as the intestinal inflammation extent and duration.
Kim YJ +7 more
europepmc +2 more sources
Effects of 2′-Fucosyllactose-Based Encapsulation on Probiotic Properties in Streptococcus thermophilus [PDF]
, 2021 Streptococcus thermophilus is widely used in dairy fermentation as a starter culture for yogurt and cheese production. Many strains are endowed with potential probiotic properties; however, since they might not survive in adequate amounts after transit ...
Corich V. +9 more
core +2 more sources
Molecules, 2022 Human milk is an intricate, bioactive food promoting infant health. We studied the composition of human milk samples collected over an 8-month lactation using 1H NMR metabolomics.
Maaria Kortesniemi +3 more
doaj +1 more source
Inulin-type fructans and 2’fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial [PDF]
, 2023 There is increasing interest in the bi-directional relationship existing between the gut and brain and the effects of both oligofructose and 2'fucosyllactose to alter microbial composition and mood state.
Robert A. Rastall +11 more
core +1 more source
Differences in the content of human milk oligosaccharides between foremilk and hind milk
Food Bioengineering, 2023 Human milk oligosaccharides (HMOs) are the second largest carbohydrate component and the third largest nutrient after lactose, and their content and composition are related to the genetic characteristics of the mother, lactation period, geography, and ...
Zhiping Pu +6 more
doaj +1 more source
Frontiers in Microbiology, 2020 Human milk oligosaccharides (hMOs) are important bioactive components in mother’s milk contributing to infant health by supporting colonization and growth of gut microbes.
Lianghui Cheng +8 more
doaj +1 more source
Microorganisms, 2023 Human milk oligosaccharides (HMOs) shape the developing infant gut microbiota. In this study, a semi-continuous colon simulator was used to evaluate the effect of 2 HMOs—2′-fucosyllactose (2′-FL) and 3-fucosyllactose (3-FL)—on the composition of infant ...
Krista Salli +7 more
doaj +1 more source