Results 111 to 120 of about 5,521 (201)

Changes in kynurenine metabolites in the gray and white matter of the dorsolateral prefrontal cortex of individuals affected by schizophrenia

Schizophrenia
Alterations in the kynurenine pathway of tryptophan metabolism have been implicated in the pathophysiology of schizophrenia. Here, we performed an in-depth analysis of all metabolites of the kynurenine pathway, i.e., tryptophan (TRY), kynurenic acid ...
Nico Antenucci, Giovanna D’Errico, Francesco Fazio, Ferdinando Nicoletti, Valeria Bruno, Giuseppe Battaglia   +5 more
doaj   +1 more source

The excretion of kynurenine and 3-hydroxykynurenine by man [PDF]

Biochemical Journal, 1954
C E, DALGLIESH, S, TEKMAN
openaire   +3 more sources

Expression analysis of novel striatal-enriched genes in Huntington disease [PDF]

, 2017
Selective degeneration of striatal neurons is a pathologic hallmark of Huntington disease (HD). The exact mechanism(s) behind this specific neurodegeneration is still unknown.
Becanovic, Kristina, Leavitt, Blair R., Luthi-Carter, Ruth, Mazarei, Gelareh, Neal, Scott J., Simpson, Elizabeth M.   +5 more
core  

Dietary advanced glycation products combined with chronic restraint stress induced anxiety-like and depression-like behaviors in male mice

npj Science of Food
Dietary advanced glycation end products (AGEs) and chronic stress might be involved in psychiatric disorders. It remains unclear whether dietary AGEs and chronic stress work together to trigger anxiety and depression.
Yebing Zhang, Kuiying Gu, Lili Xin, Yu Xia, Guoqi Yang, Jiejiao Cai, Zhilong He, Li-Qiang Qin, Zhongxiao Wan   +8 more
doaj   +1 more source

Diverse Physiological Roles of Kynurenine Pathway Metabolites: Updated Implications for Health and Disease

Metabolites
Tryptophan is an essential amino acid critical for human health. It plays a pivotal role in numerous physiological and biochemical processes through its metabolism.
Yuechang Wang, Yonggang Zhang, Wei Wang, Yanmin Zhang, Xueqian Dong, Yang Liu   +5 more
doaj   +1 more source

3-Hydroxykynurenine Transaminase Identity with Alanine Glyoxylate Transaminase [PDF]

Journal of Biological Chemistry, 2002
Qian Han, Jianmin Fang, Jianyong Li
openaire   +1 more source

The effect of dietary tryptophan levels on oxidative stress of liver induced by diquat in weaned piglets [PDF]

, 2014

core   +1 more source

3-Hydroxykynurenine, a Tryptophan Metabolite Generated during the Infection, Is Active Against Trypanosoma cruzi. [PDF]

ACS Med Chem Lett, 2017
Knubel CP, Insfran C, Martinez FF, Diaz Lujan C, Fretes RE, Theumer MG, Cervi L, Motran CC.   +7 more
europepmc   +1 more source

Increased levels of 3-hydroxykynurenine parallel disease severity in human acute pancreatitis. [PDF]

Sci Rep, 2016
Skouras C, Zheng X, Binnie M, Homer NZ, Murray TB, Robertson D, Briody L, Paterson F, Spence H, Derr L, Hayes AJ, Tsoumanis A, Lyster D, Parks RW, Garden OJ, Iredale JP, Uings IJ, Liddle J, Wright WL, Dukes G, Webster SP, Mole DJ.   +21 more
europepmc   +1 more source

3-Hydroxykynurenine and 3-Hydroxyanthranilic Acid Enhance the Toxicity Induced by Copper in Rat Astrocyte Culture. [PDF]

Oxid Med Cell Longev, 2017
Ramírez-Ortega D, Ramiro-Salazar A, González-Esquivel D, Ríos C, Pineda B, Pérez de la Cruz V.   +5 more
europepmc   +1 more source